Q2 2024 Johnson & Johnson Earnings Call

Operator: Good morning, and welcome to Johnson & Johnson's second quarter 2024 earnings conference call. All participants will be in a listen only mode until the question and answer session of the conference. This call is being recorded. If anyone has any objections, you may disconnect at this time. If you've experienced technical difficulties during the conference, you may press star zero to reach the operator. Now I'd like to turn the conference Johnson & Johnson. Please go ahead.

If you've experienced technical difficulties during the conference you May press star zero to reach the operator. Now I'd like to turn the conference Johnson and Johnson. Please go ahead.

Now I'd like to turn the conference Johnson and Johnson. Please go ahead.

Jessica Moore: Hello, everyone. This is Jessica Moore, Vice President of Investor Relations for Johnson & Johnson welcome to our company's review of the second quarter business results and our full year financial outlook for 2024. A few logistics before we get into the details. As a reminder, you can find additional materials, including today's presentation and associated schedules on the Investor Relations section of the Johnson & Johnson website at investor.j&j.com. Please note that this presentation contains forward looking statements regarding, among other things, the company's future operating and financial performance market position and business strategy. You are cautioned not to rely on these forward looking statements, which are based on the current expectations of future events using the information available as of the date of this recording and are subject to certain risks and uncertainties that may cause the company's actual results to differ materially from those projected. A description of these risks, uncertainties and other factors can be found in our SEC filings, including our 2023 Form 10-K, which is available at investor.j&j. com and on the SEC's website.

Few logistics before we get into the details. As a reminder, you can find additional materials, including today's presentation and associated schedules on the Investor Relations section of the Johnson <unk> Johnson website at Investor <unk> J&J dotcom. Please note that this presentation contains forward looking statements regarding among other things the company's future operating and financial performance market position and business strategy. You are cautioned not to rely on these forward looking statements, which are based on the current expectations of future events using the information available as of the date of this recording and are subject to certain risks and uncertainties that may cause the company's actual results to differ materially from those projected. A description of these risks uncertainties and other factors can be found in our SEC filings, including our 2023 Form 10-K, which is available at investor that J&J dot com and on the Sec's website.

As a reminder, you can find additional materials, including today's presentation and associated schedules on the Investor Relations section of the Johnson <unk> Johnson website at Investor <unk> J&J dotcom. Please note that this presentation contains forward looking statements regarding among other things the company's future operating and financial performance market position and business strategy. You are cautioned not to rely on these forward looking statements, which are based on the current expectations of future events using the information available as of the date of this recording and are subject to certain risks and uncertainties that may cause the company's actual results to differ materially from those projected. A description of these risks uncertainties and other factors can be found in our SEC filings, including our 2023 Form 10-K, which is available at investor that J&J dot com and on the Sec's website.

Please note that this presentation contains forward looking statements regarding among other things the company's future operating and financial performance market position and business strategy. You are cautioned not to rely on these forward looking statements, which are based on the current expectations of future events using the information available as of the date of this recording and are subject to certain risks and uncertainties that may cause the company's actual results to differ materially from those projected. A description of these risks uncertainties and other factors can be found in our SEC filings, including our 2023 Form 10-K, which is available at investor that J&J dot com and on the Sec's website.

You are cautioned not to rely on these forward looking statements, which are based on the current expectations of future events using the information available as of the date of this recording and are subject to certain risks and uncertainties that may cause the company's actual results to differ materially from those projected. A description of these risks uncertainties and other factors can be found in our SEC filings, including our 2023 Form 10-K, which is available at investor that J&J dot com and on the Sec's website.

A description of these risks uncertainties and other factors can be found in our SEC filings, including our 2023 Form 10-K, which is available at investor that J&J dot com and on the Sec's website.

Jessica Moore: Additionally, several of the products and compounds discussed today are being developed in collaboration with strategic partners or licensed from other companies. This slide acknowledges those relationships. Moving to today's agenda, I will start by reviewing the second quarter sales and P&L results for the corporation, as well as highlights related to our two businesses. Joe Wolk, our CFO, will then provide additional business and financial commentary before sharing an overview of our cash position, capital allocation priorities, and guidance for 2024. Joaquin Duato, our Chairman and CEO, who will then provide some closing remarks before we open it up for questions. Jennifer Taubert, John Reed, and Tim Schmid, our Innovative Medicine in MedTech Leaders will be joining us for Q&A. To ensure we provide enough time to address your questions, we anticipate the webcast will last approximately 60 minutes. Unless otherwise stated, the financial results and guidance highlighted today reflect the continuing operations of Johnson & Johnson.

Moving to today's agenda I will start by reviewing the second quarter sales and P&L results for the corporation as well as highlights related to our two businesses. Joe Walk our CFO will then provide additional business and financial commentary before sharing an overview of our cash position capital allocation priorities and guidance for 2024. Joaquin Duato, our chairman and CEO, who will then provide some closing remarks before we open it up for questions John. Jennifer Taubert, John Reed, and Ken Schmid, our innovative medicine in Med Tech leaders will be joining us for Q&A. To ensure we provide enough time to address your questions. We anticipate the webcast will last approximately 60 minutes. Unless otherwise stated the financial results and guidance highlighted today reflect the continuing operations of Johnson and Johnson.

Joe Walk our CFO will then provide additional business and financial commentary before sharing an overview of our cash position capital allocation priorities and guidance for 2024. Joaquin Duato, our chairman and CEO, who will then provide some closing remarks before we open it up for questions John. Jennifer Taubert, John Reed, and Ken Schmid, our innovative medicine in Med Tech leaders will be joining us for Q&A. To ensure we provide enough time to address your questions. We anticipate the webcast will last approximately 60 minutes. Unless otherwise stated the financial results and guidance highlighted today reflect the continuing operations of Johnson and Johnson.

Joaquin Duato: Joaquin Duato, our chairman and CEO, who will then provide some closing remarks before we open it up for questions John. Jennifer Taubert, John Reed, and Ken Schmid, our innovative medicine in Med Tech leaders will be joining us for Q&A. To ensure we provide enough time to address your questions. We anticipate the webcast will last approximately 60 minutes. Unless otherwise stated the financial results and guidance highlighted today reflect the continuing operations of Johnson and Johnson.

Jennifer Taubert, John Reed, and Ken Schmid, our innovative medicine in Med Tech leaders will be joining us for Q&A. To ensure we provide enough time to address your questions. We anticipate the webcast will last approximately 60 minutes. Unless otherwise stated the financial results and guidance highlighted today reflect the continuing operations of Johnson and Johnson.

To ensure we provide enough time to address your questions. We anticipate the webcast will last approximately 60 minutes. Unless otherwise stated the financial results and guidance highlighted today reflect the continuing operations of Johnson and Johnson.

Unless otherwise stated the financial results and guidance highlighted today reflect the continuing operations of Johnson and Johnson.

Jessica Moore: Furthermore, the percentages quoted represent operational results and therefore exclude the impact of currency translation. Turning to our second quarter sales results. Worldwide sales were $22.4 billion for the second quarter of 2024. Sales increased 6.6% with growth of 7.8% in the U.S. and 5.1% outside of the U.S. Excluding the impact of the COVID-19 vaccine, sales growth was 7.2% worldwide and growth of 6.4% outside of the U.S. Sales growth in Europe, excluding the COVID-19 vaccine, was 6%. Turning now to earnings. For the quarter, net earnings were $4.7 billion and diluted earnings per share was $1.93 versus diluted earnings per share of $2.05 a year ago. Excluding after tax intangible asset amortization expense and special items for both periods, adjusted net earnings for the quarter were $6.8 billion, and adjusted diluted earnings per share was $2.82, representing increases of 1.6% and 10.2%, respectively, compared to the second quarter of 2023. I'll comment on business sales performance in the quarter.

Turning to our second quarter sales results. Worldwide sales were $22 $4 billion for the second quarter of 2024. Sales increased six 6% with growth of seven 8% in the U S and five 1% outside of the U S. Excluding. Excluding the impact of the COVID-19 vaccine sales growth was seven 2% worldwide and growth of six 4% outside of the U S C. Sales growth in Europe, excluding the COVID-19 vaccine was 6%. Turning now to earnings. For the quarter net earnings were $4 $7 billion and diluted earnings per share was $1.93 versus diluted earnings per share of $2.05 a year ago. Excluding after tax intangible asset amortization expense and special items for both periods adjusted net earnings for the quarter were $6 $8 billion and adjusted diluted earnings per share was $2.82 representing. Increases of one, 6% and 10, 2%, respectively compared to the second quarter of 2023. I'll comment on business sales performance in the quarter.

Worldwide sales were $22 $4 billion for the second quarter of 2024. Sales increased six 6% with growth of seven 8% in the U S and five 1% outside of the U S. Excluding. Excluding the impact of the COVID-19 vaccine sales growth was seven 2% worldwide and growth of six 4% outside of the U S C. Sales growth in Europe, excluding the COVID-19 vaccine was 6%. Turning now to earnings. For the quarter net earnings were $4 $7 billion and diluted earnings per share was $1.93 versus diluted earnings per share of $2.05 a year ago. Excluding after tax intangible asset amortization expense and special items for both periods adjusted net earnings for the quarter were $6 $8 billion and adjusted diluted earnings per share was $2.82 representing. Increases of one, 6% and 10, 2%, respectively compared to the second quarter of 2023. I'll comment on business sales performance in the quarter.

Sales increased six 6% with growth of seven 8% in the U S and five 1% outside of the U S. Excluding. Excluding the impact of the COVID-19 vaccine sales growth was seven 2% worldwide and growth of six 4% outside of the U S C. Sales growth in Europe, excluding the COVID-19 vaccine was 6%. Turning now to earnings. For the quarter net earnings were $4 $7 billion and diluted earnings per share was $1.93 versus diluted earnings per share of $2.05 a year ago. Excluding after tax intangible asset amortization expense and special items for both periods adjusted net earnings for the quarter were $6 $8 billion and adjusted diluted earnings per share was $2.82 representing. Increases of one, 6% and 10, 2%, respectively compared to the second quarter of 2023. I'll comment on business sales performance in the quarter.

Excluding the impact of the COVID-19 vaccine sales growth was seven 2% worldwide and growth of six 4% outside of the U S C. Sales growth in Europe, excluding the COVID-19 vaccine was 6%. Turning now to earnings. For the quarter net earnings were $4 $7 billion and diluted earnings per share was $1.93 versus diluted earnings per share of $2.05 a year ago. Excluding after tax intangible asset amortization expense and special items for both periods adjusted net earnings for the quarter were $6 $8 billion and adjusted diluted earnings per share was $2.82 representing. Increases of one, 6% and 10, 2%, respectively compared to the second quarter of 2023. I'll comment on business sales performance in the quarter.

Sales growth in Europe, excluding the COVID-19 vaccine was 6%. Turning now to earnings. For the quarter net earnings were $4 $7 billion and diluted earnings per share was $1.93 versus diluted earnings per share of $2.05 a year ago. Excluding after tax intangible asset amortization expense and special items for both periods adjusted net earnings for the quarter were $6 $8 billion and adjusted diluted earnings per share was $2.82 representing. Increases of one, 6% and 10, 2%, respectively compared to the second quarter of 2023. I'll comment on business sales performance in the quarter.

Turning now to earnings. For the quarter net earnings were $4 $7 billion and diluted earnings per share was $1.93 versus diluted earnings per share of $2.05 a year ago. Excluding after tax intangible asset amortization expense and special items for both periods adjusted net earnings for the quarter were $6 $8 billion and adjusted diluted earnings per share was $2.82 representing. Increases of one, 6% and 10, 2%, respectively compared to the second quarter of 2023. I'll comment on business sales performance in the quarter.

For the quarter net earnings were $4 $7 billion and diluted earnings per share was $1.93 versus diluted earnings per share of $2.05 a year ago. Excluding after tax intangible asset amortization expense and special items for both periods adjusted net earnings for the quarter were $6 $8 billion and adjusted diluted earnings per share was $2.82 representing. Increases of one, 6% and 10, 2%, respectively compared to the second quarter of 2023. I'll comment on business sales performance in the quarter.

Excluding after tax intangible asset amortization expense and special items for both periods adjusted net earnings for the quarter were $6 $8 billion and adjusted diluted earnings per share was $2.82 representing. Increases of one, 6% and 10, 2%, respectively compared to the second quarter of 2023. I'll comment on business sales performance in the quarter.

Increases of one, 6% and 10, 2%, respectively compared to the second quarter of 2023. I'll comment on business sales performance in the quarter.

I'll comment on business sales performance in the quarter.

Jessica Moore: Beginning with innovative medicine, worldwide innovative medicines sales of $14.5 billion increased 7.8% with growth of 8.9% in the U.S. and 6.4% outside of the U.S. Excluding the impact of the COVID-19 vaccine, operational sales growth was 8.8% worldwide, and 8.7% outside of the U.S. Innovative medicine growth was driven by our key brands and continued uptake from recently launched products with 10 assets delivering double digit growth. We continue to drive strong sales growth across our multiple myeloma portfolio. DARZALEX growth was 21.3%, primarily driven by share gains of 4.6 points across all lines of therapy and 9.4 points in the frontline setting, as well as market growth. CARVYKTI achieved sales of $186 million with growth of 59.9% driven by continued capacity expansion, manufacturing efficiencies and strong demand.

Worldwide innovative medicines sales of $14 $5 billion increased seven 8% with growth of eight 9% in the U S and six 4% outside of the U S. Excluding the impact of the COVID-19 vaccine operational sales growth was eight 8% worldwide and eight 7% outside of the U S. Innovative medicine growth was driven by our key brands and continued uptake from recently launched products with 10 assets delivering double digit growth. We continue to drive strong sales growth across our multiple myeloma portfolio. <unk> growth was 21, 3%, primarily driven by share gains four six points across all lines of therapy and nine four points in the frontline setting as well as market growth. Perfect day achieved sales of $186 million with growth of 59, 9% driven by continued capacity expansion manufacturing efficiencies and strong demand.

Excluding the impact of the COVID-19 vaccine operational sales growth was eight 8% worldwide and eight 7% outside of the U S. Innovative medicine growth was driven by our key brands and continued uptake from recently launched products with 10 assets delivering double digit growth. We continue to drive strong sales growth across our multiple myeloma portfolio. <unk> growth was 21, 3%, primarily driven by share gains four six points across all lines of therapy and nine four points in the frontline setting as well as market growth. Perfect day achieved sales of $186 million with growth of 59, 9% driven by continued capacity expansion manufacturing efficiencies and strong demand.

Innovative medicine growth was driven by our key brands and continued uptake from recently launched products with 10 assets delivering double digit growth. We continue to drive strong sales growth across our multiple myeloma portfolio. <unk> growth was 21, 3%, primarily driven by share gains four six points across all lines of therapy and nine four points in the frontline setting as well as market growth. Perfect day achieved sales of $186 million with growth of 59, 9% driven by continued capacity expansion manufacturing efficiencies and strong demand.

We continue to drive strong sales growth across our multiple myeloma portfolio. <unk> growth was 21, 3%, primarily driven by share gains four six points across all lines of therapy and nine four points in the frontline setting as well as market growth. Perfect day achieved sales of $186 million with growth of 59, 9% driven by continued capacity expansion manufacturing efficiencies and strong demand.

<unk> growth was 21, 3%, primarily driven by share gains four six points across all lines of therapy and nine four points in the frontline setting as well as market growth. Perfect day achieved sales of $186 million with growth of 59, 9% driven by continued capacity expansion manufacturing efficiencies and strong demand.

Perfect day achieved sales of $186 million with growth of 59, 9% driven by continued capacity expansion manufacturing efficiencies and strong demand.

Jessica Moore: TECVAYLI sales achieved $135 million in the quarter with growth of 43.5%, reflecting a strong launch in the relapsed refractory setting. Demand remains strong while sequential growth slowed due to adoption of recently approved longer duration dosing intervals. EARLEADA continues to deliver strong growth of 32.5%, primarily driven by share gains and market growth in metastatic castrate sensitive prostate cancer. Other oncology growth was driven by continued strong uptake of TALVEY, our GPRC5D bispecific and RYBREVANT, our bispecific antibody for non small cell lung cancer. Within immunology, we saw sales growth in TREMFYA of 30.7% driven by market growth, share gains, and PSO and PSA, and favorable patient mix. STELARA growth of 4.9% was driven by market growth, partially offset by net unfavorable patient mix. We continue to anticipate Biosimilar entry in Europe later this month, while in the U.S., we expect continued volume growth largely offset by price declines as we move towards biosimilar entry in 2025. In neuroscience, SPRAVATO growth of 60.8% continues to be driven by increased physician and patient confidence.

Demand remains strong while sequential growth slowed due to adoption of recently approved longer duration dosing intervals. Early that continues to deliver strong growth of 32, 5%, primarily driven by share gains and market growth in metastatic castrate sensitive prostate cancer. Other oncology growth was driven by continued strong uptake of tell they are G. P. R. C. Five D by specific and ride prevent our bi specific antibody for non small cell lung cancer. Within immunology, we saw sales growth in <unk> of 37% driven by market growth share gains and P. S O on PSA and favorable patient mix. Or a growth of four 9% was driven by market growth, partially offset by net unfavorable patient mix. We continue to anticipate Biosimilar entry in Europe. Later this month well in the U S. We expect continued volume growth largely offset by price declines as we move toward. Biosimilar entry in 2025. In neuroscience provide a growth of 68% continues to be driven by increased physician and patient confidence.

Early that continues to deliver strong growth of 32, 5%, primarily driven by share gains and market growth in metastatic castrate sensitive prostate cancer. Other oncology growth was driven by continued strong uptake of tell they are G. P. R. C. Five D by specific and ride prevent our bi specific antibody for non small cell lung cancer. Within immunology, we saw sales growth in <unk> of 37% driven by market growth share gains and P. S O on PSA and favorable patient mix. Or a growth of four 9% was driven by market growth, partially offset by net unfavorable patient mix. We continue to anticipate Biosimilar entry in Europe. Later this month well in the U S. We expect continued volume growth largely offset by price declines as we move toward. Biosimilar entry in 2025. In neuroscience provide a growth of 68% continues to be driven by increased physician and patient confidence.

Other oncology growth was driven by continued strong uptake of tell they are G. P. R. C. Five D by specific and ride prevent our bi specific antibody for non small cell lung cancer. Within immunology, we saw sales growth in <unk> of 37% driven by market growth share gains and P. S O on PSA and favorable patient mix. Or a growth of four 9% was driven by market growth, partially offset by net unfavorable patient mix. We continue to anticipate Biosimilar entry in Europe. Later this month well in the U S. We expect continued volume growth largely offset by price declines as we move toward. Biosimilar entry in 2025. In neuroscience provide a growth of 68% continues to be driven by increased physician and patient confidence.

Within immunology, we saw sales growth in <unk> of 37% driven by market growth share gains and P. S O on PSA and favorable patient mix. Or a growth of four 9% was driven by market growth, partially offset by net unfavorable patient mix. We continue to anticipate Biosimilar entry in Europe. Later this month well in the U S. We expect continued volume growth largely offset by price declines as we move toward. Biosimilar entry in 2025. In neuroscience provide a growth of 68% continues to be driven by increased physician and patient confidence.

Or a growth of four 9% was driven by market growth, partially offset by net unfavorable patient mix. We continue to anticipate Biosimilar entry in Europe. Later this month well in the U S. We expect continued volume growth largely offset by price declines as we move toward. Biosimilar entry in 2025. In neuroscience provide a growth of 68% continues to be driven by increased physician and patient confidence.

Biosimilar entry in 2025. In neuroscience provide a growth of 68% continues to be driven by increased physician and patient confidence.

In neuroscience provide a growth of 68% continues to be driven by increased physician and patient confidence.

Jessica Moore: In pulmonary hypertension, OPSUMIT grew 9.1% due to share gains and market growth, partially offset by unfavorable mix. UPTRAVI growth of 8.1% was driven by market growth and share gains, partially offset by inventory dynamics. Total innovative medicine sales growth was partially offset by a decline in other neuroscience, unfavorable patient mix in [inaudible], and competitive pressures in IMBRUVICA. I'll now turn your attention to MedTech. Worldwide MedTech sales of $8 billion increased 4.4% with growth in the U.S. of 5.7% and 3.2% outside of the U.S. Acquisitions and divestitures had a positive impact of 40 basis points on sales growth in the quarter. Growth was driven by commercial execution, strength of new product introductions, and continued strong procedure volume, partially offset by performance in China and competitive pressures in U.S. distributor stocking dynamics in vision. In cardiovascular, electrophysiology delivered double digit growth of 13.4% with strong growth across all regions. Performance was driven by global procedure growth, new product uptake, and commercial execution, partially offset by the previous one-time inventory build in Asia Pacific from the prior quarter. In addition, Abiomed delivered growth of 15.4%, driven by double digit growth in all regions, and continued strong adoption of Impella 5.5 and Impella RP technology.

Total innovative medicine sales growth was partially offset by a decline in other neuroscience unfavorable patient makes sense or alto and competitive pressures and improve our cost. I'll now turn your attention to med Tech. Worldwide Med Tech sales of $8 billion increased four 4% with growth in the U S of five 7% and three 2% outside of the U S acquisitions and divestitures had a positive impact of 40 basis points on sales growth in the quarter. Growth was driven by commercial execution strength of new product introductions and continued strong procedure volume, partially offset by performance in China and competitive pressures in U S distributor stocking dynamics in vision. In cardiovascular electrophysiology delivered double digit growth of 13, 4% with strong growth across all regions. Performance was driven by global procedure growth, new product uptake and commercial execution, partially offset by the previous one time inventory build in Asia Pacific from the prior quarter. In addition, abiomed delivered growth of 15, 4% driven by double digit growth in.

I'll now turn your attention to med Tech. Worldwide Med Tech sales of $8 billion increased four 4% with growth in the U S of five 7% and three 2% outside of the U S acquisitions and divestitures had a positive impact of 40 basis points on sales growth in the quarter. Growth was driven by commercial execution strength of new product introductions and continued strong procedure volume, partially offset by performance in China and competitive pressures in U S distributor stocking dynamics in vision. In cardiovascular electrophysiology delivered double digit growth of 13, 4% with strong growth across all regions. Performance was driven by global procedure growth, new product uptake and commercial execution, partially offset by the previous one time inventory build in Asia Pacific from the prior quarter. In addition, abiomed delivered growth of 15, 4% driven by double digit growth in.

Worldwide Med Tech sales of $8 billion increased four 4% with growth in the U S of five 7% and three 2% outside of the U S acquisitions and divestitures had a positive impact of 40 basis points on sales growth in the quarter. Growth was driven by commercial execution strength of new product introductions and continued strong procedure volume, partially offset by performance in China and competitive pressures in U S distributor stocking dynamics in vision. In cardiovascular electrophysiology delivered double digit growth of 13, 4% with strong growth across all regions. Performance was driven by global procedure growth, new product uptake and commercial execution, partially offset by the previous one time inventory build in Asia Pacific from the prior quarter. In addition, abiomed delivered growth of 15, 4% driven by double digit growth in.

Growth was driven by commercial execution strength of new product introductions and continued strong procedure volume, partially offset by performance in China and competitive pressures in U S distributor stocking dynamics in vision. In cardiovascular electrophysiology delivered double digit growth of 13, 4% with strong growth across all regions. Performance was driven by global procedure growth, new product uptake and commercial execution, partially offset by the previous one time inventory build in Asia Pacific from the prior quarter. In addition, abiomed delivered growth of 15, 4% driven by double digit growth in.

In cardiovascular electrophysiology delivered double digit growth of 13, 4% with strong growth across all regions. Performance was driven by global procedure growth, new product uptake and commercial execution, partially offset by the previous one time inventory build in Asia Pacific from the prior quarter. In addition, abiomed delivered growth of 15, 4% driven by double digit growth in.

Performance was driven by global procedure growth, new product uptake and commercial execution, partially offset by the previous one time inventory build in Asia Pacific from the prior quarter. In addition, abiomed delivered growth of 15, 4% driven by double digit growth in.

All regions and continued strong adoption of Impella, five five and Impella RP technology.

Jessica Moore: Results include $77 million associated with the acquisition of Shockwave, which closed on may 31st. Contact lenses adjusted operational sales growth, excluding the blank divestiture, was 2.1%, growth was driven by strong performance and ACUVUE OASYS one-day family of products, partially offset by U.S. distributor, stocking dynamics and competitive pressures, and Japan macroeconomic pressure. The blank divestiture negatively impacted growth by approximately 130 basis points. Surgical vision grew 1.2% driven by TECNIS EYHANCE, our mono focal intraocular lens, partially offset by China VDP and refractive softness in the U.S. Surgery adjusted operational sales growth, excluding the [inaudible] divestiture was approximately flat. Performance was driven primarily by competitive pressures in energy and endo cutters, China VDP, prior yea, China recovery, EMEA tender timing across advanced surgery, and supply constraints and wound closure. This was partially offset by strength of new products. The [inaudible] divestiture negatively impacted growth by approximately 110 basis points. Orthopedics growth of 3.3% was driven by strong performance in hips and knees due to procedure growth, strength of new products, and EMEA tender timing in knees. This growth was partially offset by competitive pressures and impacts of China VDP in spine and sports.

Contact lenses adjusted operational sales growth, excluding the blank divestiture was two 1% growth was driven by strong performance and ask you view Oasis one day family of products, partially offset by U S distributor stocking dynamics and competitive pressures in Japan macroeconomic pressure. The blank divestiture negatively impacted growth by approximately 130 basis points. Surgical vision grew one 2% driven by tech mess I hance, our mono focal intraocular lens, partially offset by China V D P and refractive softness in the U S. Surgery adjusted operational sales growth, excluding the claret divestiture was approximately flat. Performance was driven primarily by competitive pressures in energy and Endo cutters, China V D P. Prior year, China recovery. EMEA tender timing across advanced surgery, and supply constraints and wound closure. This was partially offset by strength of new products. The declarant divestiture negatively impacted growth by approximately 110 basis points. Orthopedics growth of three 3% was driven by strong performance in hips and knees do do procedure growth strength of new products and EMEA tender timing in knees. This growth was partially offset by competitive pressures and impacts of China V. P in spine and sports now.

The blank divestiture negatively impacted growth by approximately 130 basis points. Surgical vision grew one 2% driven by tech mess I hance, our mono focal intraocular lens, partially offset by China V D P and refractive softness in the U S. Surgery adjusted operational sales growth, excluding the claret divestiture was approximately flat. Performance was driven primarily by competitive pressures in energy and Endo cutters, China V D P. Prior year, China recovery. EMEA tender timing across advanced surgery, and supply constraints and wound closure. This was partially offset by strength of new products. The declarant divestiture negatively impacted growth by approximately 110 basis points. Orthopedics growth of three 3% was driven by strong performance in hips and knees do do procedure growth strength of new products and EMEA tender timing in knees. This growth was partially offset by competitive pressures and impacts of China V. P in spine and sports now.

Surgical vision grew one 2% driven by tech mess I hance, our mono focal intraocular lens, partially offset by China V D P and refractive softness in the U S. Surgery adjusted operational sales growth, excluding the claret divestiture was approximately flat. Performance was driven primarily by competitive pressures in energy and Endo cutters, China V D P. Prior year, China recovery. EMEA tender timing across advanced surgery, and supply constraints and wound closure. This was partially offset by strength of new products. The declarant divestiture negatively impacted growth by approximately 110 basis points. Orthopedics growth of three 3% was driven by strong performance in hips and knees do do procedure growth strength of new products and EMEA tender timing in knees. This growth was partially offset by competitive pressures and impacts of China V. P in spine and sports now.

Surgery adjusted operational sales growth, excluding the claret divestiture was approximately flat. Performance was driven primarily by competitive pressures in energy and Endo cutters, China V D P. Prior year, China recovery. EMEA tender timing across advanced surgery, and supply constraints and wound closure. This was partially offset by strength of new products. The declarant divestiture negatively impacted growth by approximately 110 basis points. Orthopedics growth of three 3% was driven by strong performance in hips and knees do do procedure growth strength of new products and EMEA tender timing in knees. This growth was partially offset by competitive pressures and impacts of China V. P in spine and sports now.

Performance was driven primarily by competitive pressures in energy and Endo cutters, China V D P. Prior year, China recovery. EMEA tender timing across advanced surgery, and supply constraints and wound closure. This was partially offset by strength of new products. The declarant divestiture negatively impacted growth by approximately 110 basis points. Orthopedics growth of three 3% was driven by strong performance in hips and knees do do procedure growth strength of new products and EMEA tender timing in knees. This growth was partially offset by competitive pressures and impacts of China V. P in spine and sports now.

EMEA tender timing across advanced surgery, and supply constraints and wound closure. This was partially offset by strength of new products. The declarant divestiture negatively impacted growth by approximately 110 basis points. Orthopedics growth of three 3% was driven by strong performance in hips and knees do do procedure growth strength of new products and EMEA tender timing in knees. This growth was partially offset by competitive pressures and impacts of China V. P in spine and sports now.

The declarant divestiture negatively impacted growth by approximately 110 basis points. Orthopedics growth of three 3% was driven by strong performance in hips and knees do do procedure growth strength of new products and EMEA tender timing in knees. This growth was partially offset by competitive pressures and impacts of China V. P in spine and sports now.

Orthopedics growth of three 3% was driven by strong performance in hips and knees do do procedure growth strength of new products and EMEA tender timing in knees. This growth was partially offset by competitive pressures and impacts of China V. P in spine and sports now.

Jessica Moore: Now turning to our consolidated statement of earnings for the second quarter of 2024. I'd like to highlight a few noteworthy items that have changed compared to the same quarter of last year. Cost of products sold margin deleveraged by 60 basis points, primarily driven by product mix within innovative medicine and macroeconomic factors across both sectors. We continue to invest strategically in research and development at competitive levels investing $3.4 billion or 15.3% of sales this quarter. We invested $2.7 billion or 18.8% of sales and innovative medicine compared to 22.2% of sales in 2023. As a reminder, last year included an upfront payment of $245 million associated with the [inaudible] partnership. In Med Tech, R&D investment was $0.7 billion, or 9% of sales, an increase driven by continued investment in strategic platforms. Other income and expense was a net expense of $653 million in the second quarter of 2024, compared to income of $384 million in the second quarter of 2023. The increase in expense was primarily driven by costs related to the closing of the Shockwave acquisition, the loss on the completion of the debt for equity exchange of the retained stake in [inaudible] and prior year favorable intellectual property litigation settlements in Med Tech. This was partially offset by the gay.

Jessica Moore: Now turning to our consolidated statement of earnings for the second quarter of 2024. I'd like to highlight a few noteworthy items that have changed compared to the same quarter of last year. Cost of products sold margin deleveraged by 60 basis points, primarily driven by product mix within innovative medicine and macroeconomic factors across both sectors. We continue to invest strategically in research and development at competitive levels investing $3.4 billion or 15.3% of sales this quarter. We invested $2.7 billion or 18.8% of sales and innovative medicine compared to 22.2% of sales in 2023. As a reminder, last year included an upfront payment of $245 million associated with the [inaudible] partnership. In MedTech, R&D investment was $0.7 billion, or 9% of sales, an increase driven by continued investment in strategic platforms. Other income and expense was a net expense of $653 million in the second quarter of 2024, compared to income of $384 million in the second quarter of 2023. The increase in expense was primarily driven by costs related to the closing of the Shockwave acquisition, the loss on the completion of the debt for equity exchange of the retained stake in [inaudible] and prior year favorable intellectual property litigation settlements in MedTech.

I'd like to highlight a few noteworthy items that have changed compared to the same quarter of last year. Cost of products sold margin Deleveraged by 60 basis points, primarily driven by product mix within innovative medicine and macroeconomic factors across both sectors. We continue to invest strategically in research and development at competitive levels investing $3 $4 billion or 15, 3% of sales. This quarter, we invested $2 $7 billion or 18, 8% of sales and innovative medicine compared to 22, 2% of sales. In 2023 as a reminder, last year included an upfront payment of $245 million associated with the Ables Ada partnership and. In Med Tech R&D investment was $7 billion or 9% of sales an increase driven by continued investment in strategic platforms. Other income and expense was a net expense of $653 million in the second quarter of 2024 compared to income of $384 million in the second quarter of 2023. The increase in expense was primarily driven by costs related to the closing of the shops, maybe the acquisition the loss on the completion of the debt for equity exchange of the retained stake in can view and prior year favorable intellectual property litigation settlements in Med Tech. This was partially offset by the gay.

Cost of products sold margin Deleveraged by 60 basis points, primarily driven by product mix within innovative medicine and macroeconomic factors across both sectors. We continue to invest strategically in research and development at competitive levels investing $3 $4 billion or 15, 3% of sales. This quarter, we invested $2 $7 billion or 18, 8% of sales and innovative medicine compared to 22, 2% of sales. In 2023 as a reminder, last year included an upfront payment of $245 million associated with the Ables Ada partnership and. In Med Tech R&D investment was $7 billion or 9% of sales an increase driven by continued investment in strategic platforms. Other income and expense was a net expense of $653 million in the second quarter of 2024 compared to income of $384 million in the second quarter of 2023. The increase in expense was primarily driven by costs related to the closing of the shops, maybe the acquisition the loss on the completion of the debt for equity exchange of the retained stake in can view and prior year favorable intellectual property litigation settlements in Med Tech. This was partially offset by the gay.

We continue to invest strategically in research and development at competitive levels investing $3 $4 billion or 15, 3% of sales. This quarter, we invested $2 $7 billion or 18, 8% of sales and innovative medicine compared to 22, 2% of sales. In 2023 as a reminder, last year included an upfront payment of $245 million associated with the Ables Ada partnership and. In Med Tech R&D investment was $7 billion or 9% of sales an increase driven by continued investment in strategic platforms. Other income and expense was a net expense of $653 million in the second quarter of 2024 compared to income of $384 million in the second quarter of 2023. The increase in expense was primarily driven by costs related to the closing of the shops, maybe the acquisition the loss on the completion of the debt for equity exchange of the retained stake in can view and prior year favorable intellectual property litigation settlements in Med Tech. This was partially offset by the gay.

In 2023 as a reminder, last year included an upfront payment of $245 million associated with the Ables Ada partnership and. In Med Tech R&D investment was $7 billion or 9% of sales an increase driven by continued investment in strategic platforms. Other income and expense was a net expense of $653 million in the second quarter of 2024 compared to income of $384 million in the second quarter of 2023. The increase in expense was primarily driven by costs related to the closing of the shops, maybe the acquisition the loss on the completion of the debt for equity exchange of the retained stake in can view and prior year favorable intellectual property litigation settlements in Med Tech. This was partially offset by the gay.

In Med Tech R&D investment was $7 billion or 9% of sales an increase driven by continued investment in strategic platforms. Other income and expense was a net expense of $653 million in the second quarter of 2024 compared to income of $384 million in the second quarter of 2023. The increase in expense was primarily driven by costs related to the closing of the shops, maybe the acquisition the loss on the completion of the debt for equity exchange of the retained stake in can view and prior year favorable intellectual property litigation settlements in Med Tech. This was partially offset by the gay.

Other income and expense was a net expense of $653 million in the second quarter of 2024 compared to income of $384 million in the second quarter of 2023. The increase in expense was primarily driven by costs related to the closing of the shops, maybe the acquisition the loss on the completion of the debt for equity exchange of the retained stake in can view and prior year favorable intellectual property litigation settlements in Med Tech. This was partially offset by the gay.

The increase in expense was primarily driven by costs related to the closing of the shops, maybe the acquisition the loss on the completion of the debt for equity exchange of the retained stake in can view and prior year favorable intellectual property litigation settlements in Med Tech. This was partially offset by the gay.

Jessica Moore: This was partially offset by the gaining on the [inaudible] divestiture. Regarding taxes in the quarter, our effective tax rate was 18.5% versus 14.7% in the same period last year. This increase was primarily driven by unfavorable one-time international audit settlements and the continued impact from Pillar 2. Excluding special items, the effective tax rate was 18.6% versus 15.9% in the same period last year. I encourage you to review our upcoming second quarter 10-Q filing for additional details on specific tax related matters. Lastly, I direct your attention to the box section of the slide where we have also provided our income before tax, net earnings, and earnings per share, adjusted to exclude the impact of intangible amortization expense and special items. Now, let's look at adjusted income before tax by segment. In the second quarter of 2024, our adjusted income before tax for the enterprise, as a percentage of sales, increased from 37.2% to 37.4%. Innovative medicines margin improved from 42.3% to 44.6%, primarily driven by an upfront payment of $245 million associated with the [inaudible] partnership in 2023, partially offset by product mix and cost of products sold. MedTech margin declined from 28.2% to 25.7% driven by prior year favorable intellectual property litigation settlement worth approximately 300 basis points. This concludes the sales and earnings portion of the call. I'm now pleased to turn it over to Joe.

Joaquin Duato: <unk> on the of Claret divestiture. Regarding taxes in the quarter, our effective tax rate was 18, 5% versus 14, 7% in the same period last year. This. This increase was primarily driven by unfavorable one time international audit settlements and the continued impact from pillar two. Excluding special items, the effective tax rate was 18, 6% versus 15.9% in the same period last year. I encourage you to review our upcoming second quarter 10-Q filing for additional details on specific tax related matters.

Regarding taxes in the quarter, our effective tax rate was 18, 5% versus 14, 7% in the same period last year. This. This increase was primarily driven by unfavorable one time international audit settlements and the continued impact from pillar two. Excluding special items, the effective tax rate was 18, 6% versus 15.9% in the same period last year. I encourage you to review our upcoming second quarter 10-Q filing for additional details on specific tax related matters.

This increase was primarily driven by unfavorable one time international audit settlements and the continued impact from pillar two. Excluding special items, the effective tax rate was 18, 6% versus 15.9% in the same period last year. I encourage you to review our upcoming second quarter 10-Q filing for additional details on specific tax related matters.

Excluding special items, the effective tax rate was 18, 6% versus 15.9% in the same period last year. I encourage you to review our upcoming second quarter 10-Q filing for additional details on specific tax related matters.

I encourage you to review our upcoming second quarter 10-Q filing for additional details on specific tax related matters.

Lastly, I direct your attention to the box section of the slide where we have also provided our income before tax net earnings and earnings per share adjusted to exclude the impact of intangible amortization expense and special items.

Jessica Moore: Now, let's look at adjusted income before tax by segment. In the second quarter of 2024, our adjusted income before tax for the enterprise as a percentage of sales increased from 37, 2% to 37, 4%. Innovative medicines margin improved from 42, 3% to 44, 6%, primarily driven by an upfront payment of $245 million associated with the April data partnership in 2023, partially offset by product mix and cost of products sold. Med Tech margin declined from 28, 2% to 25, 7% driven by prior year favorable intellectual property litigation settlement worth approximately 300 basis points. This concludes the sales and earnings portion of the call I'm now pleased to turn it over to Joe.

In the second quarter of 2024, our adjusted income before tax for the enterprise as a percentage of sales increased from 37, 2% to 37, 4%. Innovative medicines margin improved from 42, 3% to 44, 6%, primarily driven by an upfront payment of $245 million associated with the April data partnership in 2023, partially offset by product mix and cost of products sold. Med Tech margin declined from 28, 2% to 25, 7% driven by prior year favorable intellectual property litigation settlement worth approximately 300 basis points. This concludes the sales and earnings portion of the call I'm now pleased to turn it over to Joe.

Innovative medicines margin improved from 42, 3% to 44, 6%, primarily driven by an upfront payment of $245 million associated with the April data partnership in 2023, partially offset by product mix and cost of products sold. Med Tech margin declined from 28, 2% to 25, 7% driven by prior year favorable intellectual property litigation settlement worth approximately 300 basis points. This concludes the sales and earnings portion of the call I'm now pleased to turn it over to Joe.

Med Tech margin declined from 28, 2% to 25, 7% driven by prior year favorable intellectual property litigation settlement worth approximately 300 basis points. This concludes the sales and earnings portion of the call I'm now pleased to turn it over to Joe.

Joseph J. Wolk: Thank you, Jessica, and hello, everyone. Thank you for joining today's call. Overall, Johnson & Johnson delivered solid top and bottom line as well as free cash flow growth in the quarter. Our innovative medicine business made great progress in the second quarter, we have strong momentum with key end market products and continue to advance our pipeline with significant clinical and regulatory milestones being attained. Our MedTech business delivered growth of fell below our expectations of growing in the upper range of our markets, which as you recall correlates to a weighted average market growth rate of 5% to 7% from 2022 through 2027. We came into the year thinking 2024 would be in the upper end of that range with acceleration planned in the second half, given some of the first half dynamics Jessica outlined, we now expect growth closer to 6% for 2024. To me, this reflects the power and breadth of our company, where we can more than offset quarterly volatility in one part with over performance from another part of our business.

Our innovative medicine business made great progress in the second quarter, we have strong momentum with key end market products and continue to advance our pipeline with significant clinical and regulatory milestones being attained. Our med tech business delivered growth of fell below our expectations of growing in the upper range of our markets, which as you recall correlates to a weighted average market growth rate of 5% to 7% from 2022 through 2027, we came into the year thinking 2024 would be in the upper end of that range with <unk>. Celebration planned in the second half given some of the first half dynamics Jessica outlined we now expect growth closer to 6% for 2024. To me this reflects the power and breadth of our company, where we can more than offset quarterly volatility in one part with over performance from another part of our business.

Our med tech business delivered growth of fell below our expectations of growing in the upper range of our markets, which as you recall correlates to a weighted average market growth rate of 5% to 7% from 2022 through 2027, we came into the year thinking 2024 would be in the upper end of that range with <unk>. Celebration planned in the second half given some of the first half dynamics Jessica outlined we now expect growth closer to 6% for 2024. To me this reflects the power and breadth of our company, where we can more than offset quarterly volatility in one part with over performance from another part of our business.

Celebration planned in the second half given some of the first half dynamics Jessica outlined we now expect growth closer to 6% for 2024. To me this reflects the power and breadth of our company, where we can more than offset quarterly volatility in one part with over performance from another part of our business.

To me this reflects the power and breadth of our company, where we can more than offset quarterly volatility in one part with over performance from another part of our business.

Joseph J. Wolk: Before I get into the numbers, I'd like to provide some qualitative business highlights from the quarter. Starting with innovative medicine, in oncology, we continue to make meaningful progress across our disease areas of focus. Of note, we received FDA approval for CARVIKTY in earlier lines of therapy and reported positive topline overall survival results from the CARTITUDE-4 study. We also submitted a filing with the FDA for a subcutaneous formulation of RYBREVANT. We presented updated results for TAR-200, and TAR-210. We met primary endpoints for two doors like studies, [inaudible] and AQUILA where results will be presented in an upcoming major medical meeting. Turning to immunology, we achieved key milestones for TREMFYA and inflammatory bowel disease, including the presentation and filing of Phase III studies in ulcerative colitis and Crohn's disease. As well as the filing of our subcutaneous formulation, which would make TREMFYA the only IL23 inhibitor with a fully subcutaneous regimen. We also expanded our immunology portfolio with the acquisitions of Proteologix and NM26. These bispecific antibodies will further strengthen our portfolio and enhance our ability to address significant unmet need in atopic dermatitis.

Starting with innovative medicine in oncology, we continue to make meaningful progress across our disease areas of focus of no. We received FDA approval for court victory in earlier lines of therapy and reported positive topline overall survival results from the quarter to four study. We also submitted a filing with the F D. A who are a subcutaneous formulation of <unk>. We presented updated results for <unk> 200, and hard to 10. We met primary endpoints for two doors like studies selfish and Aquila where results will be presented in an upcoming major medical meeting. Turning to immunology, we achieved key milestones for trim fire and inflammatory bowel disease, including the presentation and filing of phase III studies in ulcerative colitis and Crohn's disease. As well as the filing of our subcutaneous formulation, which would make sure fire. The only IL 23 inhibitor with a fully subcutaneous regimen. We also expanded our immunology portfolio with the acquisitions of Proteolix and M. Twenty-six. These bi specific antibodies will further strengthen our portfolio and enhance our ability to address significant unmet need in atopic dermatitis.

We also submitted a filing with the F D. A who are a subcutaneous formulation of <unk>. We presented updated results for <unk> 200, and hard to 10. We met primary endpoints for two doors like studies selfish and Aquila where results will be presented in an upcoming major medical meeting. Turning to immunology, we achieved key milestones for trim fire and inflammatory bowel disease, including the presentation and filing of phase III studies in ulcerative colitis and Crohn's disease. As well as the filing of our subcutaneous formulation, which would make sure fire. The only IL 23 inhibitor with a fully subcutaneous regimen. We also expanded our immunology portfolio with the acquisitions of Proteolix and M. Twenty-six. These bi specific antibodies will further strengthen our portfolio and enhance our ability to address significant unmet need in atopic dermatitis.

We presented updated results for <unk> 200, and hard to 10. We met primary endpoints for two doors like studies selfish and Aquila where results will be presented in an upcoming major medical meeting. Turning to immunology, we achieved key milestones for trim fire and inflammatory bowel disease, including the presentation and filing of phase III studies in ulcerative colitis and Crohn's disease. As well as the filing of our subcutaneous formulation, which would make sure fire. The only IL 23 inhibitor with a fully subcutaneous regimen. We also expanded our immunology portfolio with the acquisitions of Proteolix and M. Twenty-six. These bi specific antibodies will further strengthen our portfolio and enhance our ability to address significant unmet need in atopic dermatitis.

We met primary endpoints for two doors like studies selfish and Aquila where results will be presented in an upcoming major medical meeting. Turning to immunology, we achieved key milestones for trim fire and inflammatory bowel disease, including the presentation and filing of phase III studies in ulcerative colitis and Crohn's disease. As well as the filing of our subcutaneous formulation, which would make sure fire. The only IL 23 inhibitor with a fully subcutaneous regimen. We also expanded our immunology portfolio with the acquisitions of Proteolix and M. Twenty-six. These bi specific antibodies will further strengthen our portfolio and enhance our ability to address significant unmet need in atopic dermatitis.

Turning to immunology, we achieved key milestones for trim fire and inflammatory bowel disease, including the presentation and filing of phase III studies in ulcerative colitis and Crohn's disease. As well as the filing of our subcutaneous formulation, which would make sure fire. The only IL 23 inhibitor with a fully subcutaneous regimen. We also expanded our immunology portfolio with the acquisitions of Proteolix and M. Twenty-six. These bi specific antibodies will further strengthen our portfolio and enhance our ability to address significant unmet need in atopic dermatitis.

As well as the filing of our subcutaneous formulation, which would make sure fire. The only IL 23 inhibitor with a fully subcutaneous regimen. We also expanded our immunology portfolio with the acquisitions of Proteolix and M. Twenty-six. These bi specific antibodies will further strengthen our portfolio and enhance our ability to address significant unmet need in atopic dermatitis.

We also expanded our immunology portfolio with the acquisitions of Proteolix and M. Twenty-six. These bi specific antibodies will further strengthen our portfolio and enhance our ability to address significant unmet need in atopic dermatitis.

Joseph J. Wolk: Finally, spanning immunology and neuroscience, we presented positive results for nipocalimab in Sjogren's disease and myasthenia gravis. But it doesn't stop with the second quarter, we are excited for what awaits in the second half of this year with the anticipated approval and launch of both RYBREVANT, plus lazertinib and frontline EGFR positive lung cancer, and TREMFYA in IBD. We also expect data from J&J2113, a targeted oral peptide in psoriasis and ulcerative colitis, J&J4804 our co-antibody therapeutic in IBD and nipocalimab in rheumatoid arthritis. As we continue to bring new innovations to market and execute against our clinical and regulatory milestones, innovative medicine is well positioned to achieve sustainable growth in both the near and long term. Turning to MedTech, we continue to advance our pipeline, launched new commercial products and integrate strategic acquisitions that broaden and further differentiate our portfolio. In cardiovascular we are enhancing our portfolio and shifting into higher growth markets through strategic acquisitions, such as Shockwave Medical. In May, we announced the launch of our CARTO 3 version 8 electoral anatomical mapping system. This is the latest version of our 3D heart mapping system, which has machine learning capabilities that increase efficiency, reproducibility, and accuracy and maps electrophysiologist used to treat atrial fibrillation and other arrhythmias. In pulse field ablation, we initiated the commercial launch of the viral pulse platform in the EU and Japan, receiving early positive physician feedback in the external evaluation period.

But it doesn't stop with the second quarter, we are excited for what our weights in the second half of this year with the anticipated approval and launch of both the librarian, plus lacertid and frontline Egfr positive lung cancer and from fire and IBD. We also expect data from J&J to 113. Targeted oral peptide in psoriasis and ulcerative colitis, J&J for 804 or co antibody therapeutic in IBD and nipper kalamata in rheumatoid arthritis. As we continue to bring new innovations to market and execute against our clinical and regulatory milestones innovative medicine is well positioned to achieve sustainable growth in both the near and long term. Turning to Med Tech, we continue to advance our pipeline launched new commercial products and integrate strategic acquisitions that broaden and further differentiate our portfolio in. In cardiovascular we are enhancing our portfolio and shifting into higher growth markets through strategic acquisitions, such as Shockwave medical. In May we announced the launch of our cargo three version eight electoral anatomical mapping system. This is the latest version of our three D heart mapping system, which has machine learning capabilities that increase efficiency reproducibility and accuracy and maps electrophysiologist used to treat atrial fibrillation and other arrhythmias. Impulse field ablation, we initiated the commercial launch of the viral pulse platform in the EU and Japan, receiving early positive physician feedback in the external evaluation period.

Targeted oral peptide in psoriasis and ulcerative colitis, J&J for 804 or co antibody therapeutic in IBD and nipper kalamata in rheumatoid arthritis. As we continue to bring new innovations to market and execute against our clinical and regulatory milestones innovative medicine is well positioned to achieve sustainable growth in both the near and long term. Turning to Med Tech, we continue to advance our pipeline launched new commercial products and integrate strategic acquisitions that broaden and further differentiate our portfolio in. In cardiovascular we are enhancing our portfolio and shifting into higher growth markets through strategic acquisitions, such as Shockwave medical. In May we announced the launch of our cargo three version eight electoral anatomical mapping system. This is the latest version of our three D heart mapping system, which has machine learning capabilities that increase efficiency reproducibility and accuracy and maps electrophysiologist used to treat atrial fibrillation and other arrhythmias. Impulse field ablation, we initiated the commercial launch of the viral pulse platform in the EU and Japan, receiving early positive physician feedback in the external evaluation period.

As we continue to bring new innovations to market and execute against our clinical and regulatory milestones innovative medicine is well positioned to achieve sustainable growth in both the near and long term. Turning to Med Tech, we continue to advance our pipeline launched new commercial products and integrate strategic acquisitions that broaden and further differentiate our portfolio in. In cardiovascular we are enhancing our portfolio and shifting into higher growth markets through strategic acquisitions, such as Shockwave medical. In May we announced the launch of our cargo three version eight electoral anatomical mapping system. This is the latest version of our three D heart mapping system, which has machine learning capabilities that increase efficiency reproducibility and accuracy and maps electrophysiologist used to treat atrial fibrillation and other arrhythmias. Impulse field ablation, we initiated the commercial launch of the viral pulse platform in the EU and Japan, receiving early positive physician feedback in the external evaluation period.

Turning to Med Tech, we continue to advance our pipeline launched new commercial products and integrate strategic acquisitions that broaden and further differentiate our portfolio in. In cardiovascular we are enhancing our portfolio and shifting into higher growth markets through strategic acquisitions, such as Shockwave medical. In May we announced the launch of our cargo three version eight electoral anatomical mapping system. This is the latest version of our three D heart mapping system, which has machine learning capabilities that increase efficiency reproducibility and accuracy and maps electrophysiologist used to treat atrial fibrillation and other arrhythmias. Impulse field ablation, we initiated the commercial launch of the viral pulse platform in the EU and Japan, receiving early positive physician feedback in the external evaluation period.

In cardiovascular we are enhancing our portfolio and shifting into higher growth markets through strategic acquisitions, such as Shockwave medical. In May we announced the launch of our cargo three version eight electoral anatomical mapping system. This is the latest version of our three D heart mapping system, which has machine learning capabilities that increase efficiency reproducibility and accuracy and maps electrophysiologist used to treat atrial fibrillation and other arrhythmias. Impulse field ablation, we initiated the commercial launch of the viral pulse platform in the EU and Japan, receiving early positive physician feedback in the external evaluation period.

In May we announced the launch of our cargo three version eight electoral anatomical mapping system. This is the latest version of our three D heart mapping system, which has machine learning capabilities that increase efficiency reproducibility and accuracy and maps electrophysiologist used to treat atrial fibrillation and other arrhythmias. Impulse field ablation, we initiated the commercial launch of the viral pulse platform in the EU and Japan, receiving early positive physician feedback in the external evaluation period.

This is the latest version of our three D heart mapping system, which has machine learning capabilities that increase efficiency reproducibility and accuracy and maps electrophysiologist used to treat atrial fibrillation and other arrhythmias. Impulse field ablation, we initiated the commercial launch of the viral pulse platform in the EU and Japan, receiving early positive physician feedback in the external evaluation period.

Impulse field ablation, we initiated the commercial launch of the viral pulse platform in the EU and Japan, receiving early positive physician feedback in the external evaluation period.

Joseph J. Wolk: We also delivered results from the pivotal Phase of the admire trial, where the [inaudible] pulse platform demonstrated 85% peak primary effectiveness with minimal adverse events, short PSA application times, and low fluoroscopy exposure. In Orthopedics, we received five 10-K FDA clearance for the clinical application of the Dallas robotic assisted solution and unique compartmental knee arthroplasty. This is designed for both medial and lateral procedures, enabling surgeons to guide precise implant placement without a CT scan. In surgery, we launched the Echelon 3000 in the U.S., which combines 3D stapling and gripping surface technology to enable greater staple line security. This has been shown to deliver 47% fewer leaks, reduce surgical risks, and improve surgical outcomes. In surgical vision, we launched TECNIS EYHANCE in the U.S. and head into a full market launch in the second half of 2024. For the remainder of the year, we will continue to advance our electrophysiology and cardiovascular pipelines as we prepare for the anticipated U.S. approval of [inaudible], as well as the submission of Impella ECP for regulatory approval. Within robotic surgery, we are on track to submit an investigational device exemption to the FDA for Ottava in the second half of the year. Before turning to cash flow and guidance, I wanted to provide an update on the talc litigation.

Joseph J. Wolk: We also delivered results from the pivotal Phase of the admire trial, where the [inaudible] pulse platform demonstrated 85% peak primary effectiveness with minimal adverse events, short PSA application times, and low fluoroscopy exposure. In Orthopedics, we received five 10-K FDA clearance for the clinical application of the Dallas robotic assisted solution and unique compartmental knee arthroplasty. This is designed for both medial and lateral procedures, enabling surgeons to guide precise implant placement without a CT scan. In surgery, we launched the Echelon 3000 in the U.S., which combines 3D stapling and gripping surface technology to enable greater staple line security. This has been shown to deliver 47% fewer leaks, reduce surgical risks, and improve surgical outcomes. In surgical vision, we launched TECNIS EYHANCE in the U.S. and head into a full market launch in the second half of 2024. For the remainder of the year, we will continue to advance our electrophysiology and cardiovascular pipelines as we prepare for the anticipated U.S. approval of [inaudible], as well as the submission of Impella ECP for regulatory approval. Within robotic surgery, we are on track to submit an investigational device exemption to the FDA for Ottava in the second half of the year.

In Orthopedics, we received five 10-K FDA clearance for the clinical application of the Dallas robotic assisted solution and unique compartmental knee arthroplasty. This. This is designed for both medial and lateral procedures, enabling surgeons to guide precise implant placement without a C T scan. In surgery, we launched the echelon 3000 in the U S, which combines three D stapling and gripping surface technology to enable greater staple line security. This has been shown to deliver 47% fewer leaks reduce surgical risks and improve surgical outcomes. In surgical vision, we launched Texas Odyssey in the U S and head into a full market launch in the second half of 2024. For the remainder of the year, we will continue to advance our electrophysiology and cardiovascular pipelines as we prepare for the anticipated U S approval of our pulse as well as the submission of Impella ECP for regulatory approval. Within robotic surgery, we are on track to submit an investigational device exemption to the FDA for ottava in the second half of the year. Before turning to cash flow guidance I wanted to provide an update on the talc litigation.

This is designed for both medial and lateral procedures, enabling surgeons to guide precise implant placement without a C T scan. In surgery, we launched the echelon 3000 in the U S, which combines three D stapling and gripping surface technology to enable greater staple line security. This has been shown to deliver 47% fewer leaks reduce surgical risks and improve surgical outcomes. In surgical vision, we launched Texas Odyssey in the U S and head into a full market launch in the second half of 2024. For the remainder of the year, we will continue to advance our electrophysiology and cardiovascular pipelines as we prepare for the anticipated U S approval of our pulse as well as the submission of Impella ECP for regulatory approval. Within robotic surgery, we are on track to submit an investigational device exemption to the FDA for ottava in the second half of the year. Before turning to cash flow guidance I wanted to provide an update on the talc litigation.

In surgery, we launched the echelon 3000 in the U S, which combines three D stapling and gripping surface technology to enable greater staple line security. This has been shown to deliver 47% fewer leaks reduce surgical risks and improve surgical outcomes. In surgical vision, we launched Texas Odyssey in the U S and head into a full market launch in the second half of 2024. For the remainder of the year, we will continue to advance our electrophysiology and cardiovascular pipelines as we prepare for the anticipated U S approval of our pulse as well as the submission of Impella ECP for regulatory approval. Within robotic surgery, we are on track to submit an investigational device exemption to the FDA for ottava in the second half of the year. Before turning to cash flow guidance I wanted to provide an update on the talc litigation.

In surgical vision, we launched Texas Odyssey in the U S and head into a full market launch in the second half of 2024. For the remainder of the year, we will continue to advance our electrophysiology and cardiovascular pipelines as we prepare for the anticipated U S approval of our pulse as well as the submission of Impella ECP for regulatory approval. Within robotic surgery, we are on track to submit an investigational device exemption to the FDA for ottava in the second half of the year. Before turning to cash flow guidance I wanted to provide an update on the talc litigation.

For the remainder of the year, we will continue to advance our electrophysiology and cardiovascular pipelines as we prepare for the anticipated U S approval of our pulse as well as the submission of Impella ECP for regulatory approval. Within robotic surgery, we are on track to submit an investigational device exemption to the FDA for ottava in the second half of the year. Before turning to cash flow guidance I wanted to provide an update on the talc litigation.

Within robotic surgery, we are on track to submit an investigational device exemption to the FDA for ottava in the second half of the year. Before turning to cash flow guidance I wanted to provide an update on the talc litigation.

Joseph J. Wolk: Before turning to cash flow and guidance, I wanted to provide an update on the talc litigation. As announced on May 1st, the company has committed to pay over an [inaudible] are present value of approximately $6.5 billion or $8 billion nominally over 25 years ,resolving 99.75% of all pending talc law suits against the company and its affiliates in the United States. We are currently in a voting period for the plan, where for the first time, claimants are able to vote for themselves for or against the plan. The last day of voting is scheduled for July 26th. It will then take a few weeks for the vote administrator to vet and tally the votes. Once that process concludes, we plan to make a public announcement on the next steps regarding a pre packaged bankruptcy filing. Our confidence that we will reach the requisite 75% vote is bolstered by the continued support of counsel representing the vast majority of claimants with whom the plan was developed, as well as the announcements of support by additional prominent plaintiff law firms recently, including [inaudible] Stock, [inaudible] and Miller. Additionally, in furtherance of our goal of achieving a comprehensive solution, we finalized the previously announced agreements reached with all states that advanced health claims in the Emirates and Cypress entities, owners of the minds that supplied talc to the company. In the second quarter, we continued to make progress with mesothelioma claimants with 95% of claimants now settled.

Before turning to cash flow guidance I wanted to provide an update on the talc litigation.

As announced on May 1st the company has committed to pay ovarian claimants are present value of approximately $6 $5 billion or $8 billion nominally over 25 years resolving 90, 975% of all pending tax law suits against the company and its affiliates in the United States. We are currently in a voting period for the plant where for the first time claimants, who are able to vote for themselves for or against the plan. The last day of voting is scheduled for July 26th. It will then take a few weeks, where the vote administrator to vet and tally the votes. Once that process concludes we plants, who make a public announcement on that. Next steps regarding a pre packaged bankruptcy filing. Our confidence that we will reach the requisite 75% vote is bolstered by the continued support of counsel, representing the vast majority of claimants with whom the plan was developed as well as the announcements of support by additional prominent plaintiff law firms recently, including Al stock Hello, Postmen and Miller. Actually in furtherance of our goal of achieving a comprehensive solution. We finalize the previously announced agreements reached with all states that advanced health claims in the Emirates and Cypress entities owners of the mindset supplied talked to the company. In the second quarter, we continued to make progress with mesothelioma claimants with 95% of claimants, who now settled.

We are currently in a voting period for the plant where for the first time claimants, who are able to vote for themselves for or against the plan. The last day of voting is scheduled for July 26th. It will then take a few weeks, where the vote administrator to vet and tally the votes. Once that process concludes we plants, who make a public announcement on that. Next steps regarding a pre packaged bankruptcy filing. Our confidence that we will reach the requisite 75% vote is bolstered by the continued support of counsel, representing the vast majority of claimants with whom the plan was developed as well as the announcements of support by additional prominent plaintiff law firms recently, including Al stock Hello, Postmen and Miller. Actually in furtherance of our goal of achieving a comprehensive solution. We finalize the previously announced agreements reached with all states that advanced health claims in the Emirates and Cypress entities owners of the mindset supplied talked to the company. In the second quarter, we continued to make progress with mesothelioma claimants with 95% of claimants, who now settled.

Next steps regarding a pre packaged bankruptcy filing. Our confidence that we will reach the requisite 75% vote is bolstered by the continued support of counsel, representing the vast majority of claimants with whom the plan was developed as well as the announcements of support by additional prominent plaintiff law firms recently, including Al stock Hello, Postmen and Miller. Actually in furtherance of our goal of achieving a comprehensive solution. We finalize the previously announced agreements reached with all states that advanced health claims in the Emirates and Cypress entities owners of the mindset supplied talked to the company. In the second quarter, we continued to make progress with mesothelioma claimants with 95% of claimants, who now settled.

Our confidence that we will reach the requisite 75% vote is bolstered by the continued support of counsel, representing the vast majority of claimants with whom the plan was developed as well as the announcements of support by additional prominent plaintiff law firms recently, including Al stock Hello, Postmen and Miller. Actually in furtherance of our goal of achieving a comprehensive solution. We finalize the previously announced agreements reached with all states that advanced health claims in the Emirates and Cypress entities owners of the mindset supplied talked to the company. In the second quarter, we continued to make progress with mesothelioma claimants with 95% of claimants, who now settled.

Actually in furtherance of our goal of achieving a comprehensive solution. We finalize the previously announced agreements reached with all states that advanced health claims in the Emirates and Cypress entities owners of the mindset supplied talked to the company. In the second quarter, we continued to make progress with mesothelioma claimants with 95% of claimants, who now settled.

In the second quarter, we continued to make progress with mesothelioma claimants with 95% of claimants, who now settled.

Joseph J. Wolk: Turning to cash and capital allocation. We ended the second quarter with approximately $25 billion of cash and marketable securities, and approximately $41 billion of debt for a net debt position of $16 billion. Free cash flow year to date was approximately $7.5 billion compared to $5.5 billion in the prior year period, which included cash flow from the consumer health business. During the quarter, we exited our retained stake in [inaudible], bringing the separation to a close. The net proceeds from the secondary offering with $3.6 billion. Our capital allocation priorities remain unchanged, we maintain a strong balance sheet, which continues to enable us to strategically invest in and grow our business, while returning capital to our shareholders. Innovation remains core to our strategy. In the second quarter, we invested more than $3.4 billion or 15.3% of sales and research and development. In terms of acquisitions and licensing, during the first half of 2024, Johnson & Johnson has deployed approximately $17 billion in strategic value, creating inorganic growth opportunities. This includes Shockwave, Proteologix, and the NM26 bispecific antibody transaction announced last week, as well as more than 20 other smaller complementary business development transactions. We will always explore strategic deals of any size that can create value, we foresee modest tuck in deals as the preferred route over the near term.

Free cash flow year to date was approximately $7 $5 billion compared to $5 $5 billion in the prior year period, which included cash flow from the consumer health business. During the quarter, we exited our retained stake in can view, bringing the separation to a close the net proceeds from the secondary offering with $3 $6 billion. Our capital allocation priorities remain unchanged, we maintain a strong balance sheet, which continues to enable us to strategically invest in and grow our business, while returning capital to our shareholders. Innovation remains core to our strategy in the second quarter, we invested more than $3 $4 billion or 15, 3% of sales and research and development. In terms of acquisitions and licensing during the first half of 2020 for Johnson <unk> Johnson has deployed approximately $17 billion in strategic value, creating inorganic growth opportunities. This includes shockwave proteolix and the N M twenty-six bi specific antibody transaction announced last week as well as. More than 20, other smaller complementary business development transactions. We will always explore strategic deals of any size that can create value, we foresee modest tuck in deals as the preferred route over the near term.

During the quarter, we exited our retained stake in can view, bringing the separation to a close the net proceeds from the secondary offering with $3 $6 billion. Our capital allocation priorities remain unchanged, we maintain a strong balance sheet, which continues to enable us to strategically invest in and grow our business, while returning capital to our shareholders. Innovation remains core to our strategy in the second quarter, we invested more than $3 $4 billion or 15, 3% of sales and research and development. In terms of acquisitions and licensing during the first half of 2020 for Johnson <unk> Johnson has deployed approximately $17 billion in strategic value, creating inorganic growth opportunities. This includes shockwave proteolix and the N M twenty-six bi specific antibody transaction announced last week as well as. More than 20, other smaller complementary business development transactions. We will always explore strategic deals of any size that can create value, we foresee modest tuck in deals as the preferred route over the near term.

Our capital allocation priorities remain unchanged, we maintain a strong balance sheet, which continues to enable us to strategically invest in and grow our business, while returning capital to our shareholders. Innovation remains core to our strategy in the second quarter, we invested more than $3 $4 billion or 15, 3% of sales and research and development. In terms of acquisitions and licensing during the first half of 2020 for Johnson <unk> Johnson has deployed approximately $17 billion in strategic value, creating inorganic growth opportunities. This includes shockwave proteolix and the N M twenty-six bi specific antibody transaction announced last week as well as. More than 20, other smaller complementary business development transactions. We will always explore strategic deals of any size that can create value, we foresee modest tuck in deals as the preferred route over the near term.

Innovation remains core to our strategy in the second quarter, we invested more than $3 $4 billion or 15, 3% of sales and research and development. In terms of acquisitions and licensing during the first half of 2020 for Johnson <unk> Johnson has deployed approximately $17 billion in strategic value, creating inorganic growth opportunities. This includes shockwave proteolix and the N M twenty-six bi specific antibody transaction announced last week as well as. More than 20, other smaller complementary business development transactions. We will always explore strategic deals of any size that can create value, we foresee modest tuck in deals as the preferred route over the near term.

In terms of acquisitions and licensing during the first half of 2020 for Johnson <unk> Johnson has deployed approximately $17 billion in strategic value, creating inorganic growth opportunities. This includes shockwave proteolix and the N M twenty-six bi specific antibody transaction announced last week as well as. More than 20, other smaller complementary business development transactions. We will always explore strategic deals of any size that can create value, we foresee modest tuck in deals as the preferred route over the near term.

More than 20, other smaller complementary business development transactions. We will always explore strategic deals of any size that can create value, we foresee modest tuck in deals as the preferred route over the near term.

We will always explore strategic deals of any size that can create value, we foresee modest tuck in deals as the preferred route over the near term.

Joseph J. Wolk: Now turning to our full year 2024 guidance given the moving parts associated with the acquisitions this quarter I'll start where I, usually end up with earnings per share. Before the impact of recent acquisitions, our outlook for adjusted operational EPS performance is once again being increased is this schedule reflects we are expecting a five cent per share increase in our operational performance. This would result in year over year EPS growth of eight 2% at the midpoint. To account for the completion of Shockwave, Protium, <unk> and the N M twenty-six bi specific antibody transactions and as previously disclosed our adjusted operational EPS guidance now includes dilution of <unk> 68 per share. Combined all of this yielded an updated adjusted operational EPS guidance in the range of $10 to $10.10 per share. In addition to assist with your future models. These transactions are expected to have a smaller impact of 33 cents to adjusted operational EPS in 2025. Now to address all elements of P&L guidance for 2024 as a reminder, our sales guidance continues to exclude any impact from COVID-19 vaccine sales. We are increasing our operational sales guidance for the full year by $500 million to reflect the completion of the Shockwave acquisition. We now expect growth in the range of six 1% to six 6% compared to 2023 with a midpoint of $89 $4 billion or six 4% at the midpoint.

Before the impact of recent acquisitions, our outlook for adjusted operational EPS performance is once again being increased is this schedule reflects we are expecting a five cent per share increase in our operational performance. This would result in year over year EPS growth of eight 2% at the midpoint. To account for the completion of Shockwave, Protium, <unk> and the N M twenty-six bi specific antibody transactions and as previously disclosed our adjusted operational EPS guidance now includes dilution of <unk> 68 per share. Combined all of this yielded an updated adjusted operational EPS guidance in the range of $10 to $10.10 per share. In addition to assist with your future models. These transactions are expected to have a smaller impact of 33 cents to adjusted operational EPS in 2025. Now to address all elements of P&L guidance for 2024 as a reminder, our sales guidance continues to exclude any impact from COVID-19 vaccine sales. We are increasing our operational sales guidance for the full year by $500 million to reflect the completion of the Shockwave acquisition. We now expect growth in the range of six 1% to six 6% compared to 2023 with a midpoint of $89 $4 billion or six 4% at the midpoint.

To account for the completion of Shockwave, Protium, <unk> and the N M twenty-six bi specific antibody transactions and as previously disclosed our adjusted operational EPS guidance now includes dilution of <unk> 68 per share. Combined all of this yielded an updated adjusted operational EPS guidance in the range of $10 to $10.10 per share. In addition to assist with your future models. These transactions are expected to have a smaller impact of 33 cents to adjusted operational EPS in 2025. Now to address all elements of P&L guidance for 2024 as a reminder, our sales guidance continues to exclude any impact from COVID-19 vaccine sales. We are increasing our operational sales guidance for the full year by $500 million to reflect the completion of the Shockwave acquisition. We now expect growth in the range of six 1% to six 6% compared to 2023 with a midpoint of $89 $4 billion or six 4% at the midpoint.

Combined all of this yielded an updated adjusted operational EPS guidance in the range of $10 to $10.10 per share. In addition to assist with your future models. These transactions are expected to have a smaller impact of 33 cents to adjusted operational EPS in 2025. Now to address all elements of P&L guidance for 2024 as a reminder, our sales guidance continues to exclude any impact from COVID-19 vaccine sales. We are increasing our operational sales guidance for the full year by $500 million to reflect the completion of the Shockwave acquisition. We now expect growth in the range of six 1% to six 6% compared to 2023 with a midpoint of $89 $4 billion or six 4% at the midpoint.

In addition to assist with your future models. These transactions are expected to have a smaller impact of 33 cents to adjusted operational EPS in 2025. Now to address all elements of P&L guidance for 2024 as a reminder, our sales guidance continues to exclude any impact from COVID-19 vaccine sales. We are increasing our operational sales guidance for the full year by $500 million to reflect the completion of the Shockwave acquisition. We now expect growth in the range of six 1% to six 6% compared to 2023 with a midpoint of $89 $4 billion or six 4% at the midpoint.

Now to address all elements of P&L guidance for 2024 as a reminder, our sales guidance continues to exclude any impact from COVID-19 vaccine sales. We are increasing our operational sales guidance for the full year by $500 million to reflect the completion of the Shockwave acquisition. We now expect growth in the range of six 1% to six 6% compared to 2023 with a midpoint of $89 $4 billion or six 4% at the midpoint.

We are increasing our operational sales guidance for the full year by $500 million to reflect the completion of the Shockwave acquisition. We now expect growth in the range of six 1% to six 6% compared to 2023 with a midpoint of $89 $4 billion or six 4% at the midpoint.

We now expect growth in the range of six 1% to six 6% compared to 2023 with a midpoint of $89 $4 billion or six 4% at the midpoint.

Joseph J. Wolk: Excluding the impact from acquisitions and divestitures, we are maintaining our adjusted operational sales growth to the range of 5.5% to 6.0% compared to 2023. As you know, we don't speculate on future currency movements. We are utilizing a euro spot rate relative to the U.S. dollar of 1.08, consistent with last quarter. However, there have been notable strengthening of the U.S. dollar versus other currencies, specifically the Japanese yen and Chinese yuan. As a result, we estimate an incremental negative foreign currency impact of $500 million, resulting in a full-year impact of $1.2 billion. As such, combined with the Shockwave acquisition, we expect reported sales growth between 4.7% to 5.2%, compared to 2023 with a midpoint of $88.2 billion or 5% growth. Turning to the rest of the P&L. Based solely on the dilution from the transactions, we now anticipate our 2024 adjusted pre-tax operating margin to decline by 120 basis points, more than offsetting the previously communicated 50 basis point improvement. We projected net interest income between $300 million and $400 million, lower than previous guidance driven by interest expense associated with financing of our recent acquisitions. Other income is anticipated to be in the range of $1.5 billion to $1.7 billion, an increase versus previous guidance driven by year-to-date performance.

As you know, we don't speculate on future currency movements, we are utilizing a euro spot rate relative to the U S. Dollar of 1.08 consistent with last quarter. However, there have been notable strengthening of the U S dollar versus other currencies, specifically, the Japanese yen and Chinese Yuan. As a result, we estimate an incremental negative foreign currency impact of $500 million, resulting in a full year impact of $1 $2 billion as such combined with the Shockwave acquisition, we expect reported sales growth between four 7% to five 2% compared to 2023. With a midpoint of $88 $2 billion or 5% growth. Turning to the rest of the P&L based solely on the dilution from the transactions, we now anticipate or 'twenty 'twenty four adjusted pre tax operating margin to decline by 120 basis points more than offsetting the previously communicated 50 basis point improvement. We project net interest income between $300 million and $400 million lower than previous guidance driven by interest expense associated with financing of our recent acquisitions. Other income is anticipated to be in the range of $1 $5 billion to $1 $7 billion, an increase versus previous guidance driven by year to date performance.

As a result, we estimate an incremental negative foreign currency impact of $500 million, resulting in a full year impact of $1 $2 billion as such combined with the Shockwave acquisition, we expect reported sales growth between four 7% to five 2% compared to 2023. With a midpoint of $88 $2 billion or 5% growth. Turning to the rest of the P&L based solely on the dilution from the transactions, we now anticipate or 'twenty 'twenty four adjusted pre tax operating margin to decline by 120 basis points more than offsetting the previously communicated 50 basis point improvement. We project net interest income between $300 million and $400 million lower than previous guidance driven by interest expense associated with financing of our recent acquisitions. Other income is anticipated to be in the range of $1 $5 billion to $1 $7 billion, an increase versus previous guidance driven by year to date performance.

With a midpoint of $88 $2 billion or 5% growth. Turning to the rest of the P&L based solely on the dilution from the transactions, we now anticipate or 'twenty 'twenty four adjusted pre tax operating margin to decline by 120 basis points more than offsetting the previously communicated 50 basis point improvement. We project net interest income between $300 million and $400 million lower than previous guidance driven by interest expense associated with financing of our recent acquisitions. Other income is anticipated to be in the range of $1 $5 billion to $1 $7 billion, an increase versus previous guidance driven by year to date performance.

Turning to the rest of the P&L based solely on the dilution from the transactions, we now anticipate or 'twenty 'twenty four adjusted pre tax operating margin to decline by 120 basis points more than offsetting the previously communicated 50 basis point improvement. We project net interest income between $300 million and $400 million lower than previous guidance driven by interest expense associated with financing of our recent acquisitions. Other income is anticipated to be in the range of $1 $5 billion to $1 $7 billion, an increase versus previous guidance driven by year to date performance.

We project net interest income between $300 million and $400 million lower than previous guidance driven by interest expense associated with financing of our recent acquisitions. Other income is anticipated to be in the range of $1 $5 billion to $1 $7 billion, an increase versus previous guidance driven by year to date performance.

Other income is anticipated to be in the range of $1 $5 billion to $1 $7 billion, an increase versus previous guidance driven by year to date performance.

Joseph J. Wolk: Our effective tax rate is now expected to be between 17.5% and 18.5% for the full-year, much higher than 2023, largely due to the impact of OECD Pillar 2, as well as the non-deductible nature of the recently announced NM26 bispecific antibody acquisition. While we do not provide guidance by segment or on a quarterly basis, I'd like to provide some qualitative considerations to support your modeling. We continue to expect Innovative Medicine sales growth to be lower in the second half of the year compared to the first half, given the anticipated entry of STELARA biosimilars in Europe beginning the last week of July. This headwind will be partially offset by continued uptake from our recently launched products. While we had COVID-19 vaccine sales in the second quarter, we do not anticipate any future sales. Finally, it is worth noting that distribution rights for REMICADE and SIMPONI in Europe will be returned in the fourth quarter. In preparation for this transfer, we expect limited third-quarter sales in Europe. Turning to Med Tech, as previously stated, we expect growth to accelerate back in line with our long-term expectations in the second-half of the year. This will be driven by recovery in contact lenses, evidenced by sequential monthly improvement within Q2. Further expansion into high-growth segments, including the integration of Shockwave and continued growth of new products and commercial execution across the portfolio.

While we do not provide guidance by segment or on a quarterly basis I'd like to provide some qualitative considerations to support your modeling. We continue to expect innovative medicines sales growth to be lower in the second half of the year compared to the first half given the anticipated entry of still our Biosimilars in Europe, beginning the last week of July. This headwind will be partially offset by continued uptake from our recently launched products. While we had COVID-19 vaccine sales in the second quarter, we do not anticipate any future sales. Finally, it is worth noting the distribution rights for Remicade and Symphony in Europe will be returned in the fourth quarter in preparation for this transfer we expect limited third quarter sales in Europe. Turning to Med Tech as previously stated we expect growth to accelerate back in line with our long term expectations in the second half of the year. This will be driven by recovery in contact lenses evidenced by sequential monthly improvement within Q2. Further expansion into high growth segments, including the integration of Shockwave and continued growth of new products and commercial execution across the portfolio.

We continue to expect innovative medicines sales growth to be lower in the second half of the year compared to the first half given the anticipated entry of still our Biosimilars in Europe, beginning the last week of July. This headwind will be partially offset by continued uptake from our recently launched products. While we had COVID-19 vaccine sales in the second quarter, we do not anticipate any future sales. Finally, it is worth noting the distribution rights for Remicade and Symphony in Europe will be returned in the fourth quarter in preparation for this transfer we expect limited third quarter sales in Europe. Turning to Med Tech as previously stated we expect growth to accelerate back in line with our long term expectations in the second half of the year. This will be driven by recovery in contact lenses evidenced by sequential monthly improvement within Q2. Further expansion into high growth segments, including the integration of Shockwave and continued growth of new products and commercial execution across the portfolio.

Joaquin Duato: This headwind will be partially offset by continued uptake from our recently launched products. While we had COVID-19 vaccine sales in the second quarter, we do not anticipate any future sales. Finally, it is worth noting the distribution rights for Remicade and Symphony in Europe will be returned in the fourth quarter in preparation for this transfer we expect limited third quarter sales in Europe. Turning to Med Tech as previously stated we expect growth to accelerate back in line with our long term expectations in the second half of the year. This will be driven by recovery in contact lenses evidenced by sequential monthly improvement within Q2. Further expansion into high growth segments, including the integration of Shockwave and continued growth of new products and commercial execution across the portfolio.

While we had COVID-19 vaccine sales in the second quarter, we do not anticipate any future sales. Finally, it is worth noting the distribution rights for Remicade and Symphony in Europe will be returned in the fourth quarter in preparation for this transfer we expect limited third quarter sales in Europe. Turning to Med Tech as previously stated we expect growth to accelerate back in line with our long term expectations in the second half of the year. This will be driven by recovery in contact lenses evidenced by sequential monthly improvement within Q2. Further expansion into high growth segments, including the integration of Shockwave and continued growth of new products and commercial execution across the portfolio.

Finally, it is worth noting the distribution rights for Remicade and Symphony in Europe will be returned in the fourth quarter in preparation for this transfer we expect limited third quarter sales in Europe. Turning to Med Tech as previously stated we expect growth to accelerate back in line with our long term expectations in the second half of the year. This will be driven by recovery in contact lenses evidenced by sequential monthly improvement within Q2. Further expansion into high growth segments, including the integration of Shockwave and continued growth of new products and commercial execution across the portfolio.

Turning to Med Tech as previously stated we expect growth to accelerate back in line with our long term expectations in the second half of the year. This will be driven by recovery in contact lenses evidenced by sequential monthly improvement within Q2. Further expansion into high growth segments, including the integration of Shockwave and continued growth of new products and commercial execution across the portfolio.

This will be driven by recovery in contact lenses evidenced by sequential monthly improvement within Q2. Further expansion into high growth segments, including the integration of Shockwave and continued growth of new products and commercial execution across the portfolio.

Further expansion into high growth segments, including the integration of Shockwave and continued growth of new products and commercial execution across the portfolio.

Joseph J. Wolk: As you think about our adjusted operating margin, we continue to expect it to be higher in the first-half of the year, compared to the second-half. Again, this is due to the IP R&D charge for the NM26 bispecific antibody transaction in Q3 as well as the anticipated entry of STELARA biosimilars in Europe later this month. Lastly, as a reminder on share count, we only expect a partial benefit in the third quarter resulting from the share count reduction following the Kenvue exchange offer in August of 2023 with the fourth quarter being neutral. As we move forward, we remain focused on advancing our differentiated portfolio and achieving key clinical and regulatory milestones across Innovative Medicine and MedTech. We remain confident in our ability to deliver sustained growth and long-term value for patients, customers, and shareholders. With that, I am now pleased to turn the call over to Joaquin for concluding remarks before taking your questions.

Again this is due to the IP R&D charge for the N M twenty-six bi specific antibody transaction in Q3 as well as the anticipated entry of store of Biosimilars in Europe later this month. Lastly, as a reminder on share count, we only expect a partial benefit in the third quarter, resulting from the share count reduction following the Kennedy who exchange offer in August of 2023, with the fourth quarter being neutral. As we move forward, we remain focused on advancing our differentiated portfolio and achieving key clinical and regulatory milestones across innovative medicine and med Tech we remain confident in our ability to deliver sustained growth and long term value for patients customers and shareholders with that I am now pleased to turn the call over to Joaquin for concluding remarks. Marks before taking your questions.

Joaquin Duato: Lastly, as a reminder on share count, we only expect a partial benefit in the third quarter, resulting from the share count reduction following the Kennedy who exchange offer in August of 2023, with the fourth quarter being neutral. As we move forward, we remain focused on advancing our differentiated portfolio and achieving key clinical and regulatory milestones across innovative medicine and med Tech we remain confident in our ability to deliver sustained growth and long term value for patients customers and shareholders with that I am now pleased to turn the call over to Joaquin for concluding remarks. Marks before taking your questions.

As we move forward, we remain focused on advancing our differentiated portfolio and achieving key clinical and regulatory milestones across innovative medicine and med Tech we remain confident in our ability to deliver sustained growth and long term value for patients customers and shareholders with that I am now pleased to turn the call over to Joaquin for concluding remarks. Marks before taking your questions.

Marks before taking your questions. Thank you Joe Hello, everyone with our strong second quarter I'm excited about the rest of 'twenty 'twenty four.

Marks before taking your questions.

Joaquin Duato: Thank you, Joe, and hello, everyone. With a strong second quarter, I'm excited about the rest of 2024. Our Innovative Medicine business is on track for a 13th consecutive year of above-market growth. Our success is driven by a portfolio of innovative best and first-in-class medicines, many of which have the potential to change the practice of medicine. Across the board, oncology, immunology, neuroscience, we are reinventing treatment paradigms and transforming lives. As Joe mentioned, we have made significant progress across our pipeline. In particular, I would like to highlight two major milestones on the horizon that will help drive sustained growth through 2025 and beyond. First, the approval and launch of RYBREVANT plus lazertinib for first-line treatment of EGFR-positive non-small cell lung cancer. And second, the approval and launch of TREMFYA in Inflammatory Bowel Disease or IBD, which follows the recent presentation of data that demonstrated superiority versus STELARA.

Our innovative medicines business is on track for a set of beans consecutive year of above market growth. Our success is driven by our portfolio of innovative best of first in class, maybe it seems many of which have the potential to change the practice of medicine. Across the board oncology immunology neuroscience, we are reinventing three men part of volumes and then I'm sorry. For me lives. You mentioned, we have made significant progress across our pipeline. Particular, I would like to highlight two major milestones on the horizon that will help drive sustained growth through 'twenty 'twenty five and beyond. First the approval of launch of <unk>, plus <unk> for first line treatment of Egfr positive non small cell lung cancer and second the approval of launch of fire in inflammatory bowel disease or IBD, which follows the recent presentation of data. Once the superiority there shows the latter.

Our success is driven by our portfolio of innovative best of first in class, maybe it seems many of which have the potential to change the practice of medicine. Across the board oncology immunology neuroscience, we are reinventing three men part of volumes and then I'm sorry. For me lives. You mentioned, we have made significant progress across our pipeline. Particular, I would like to highlight two major milestones on the horizon that will help drive sustained growth through 'twenty 'twenty five and beyond. First the approval of launch of <unk>, plus <unk> for first line treatment of Egfr positive non small cell lung cancer and second the approval of launch of fire in inflammatory bowel disease or IBD, which follows the recent presentation of data. Once the superiority there shows the latter.

Across the board oncology immunology neuroscience, we are reinventing three men part of volumes and then I'm sorry. For me lives. You mentioned, we have made significant progress across our pipeline. Particular, I would like to highlight two major milestones on the horizon that will help drive sustained growth through 'twenty 'twenty five and beyond. First the approval of launch of <unk>, plus <unk> for first line treatment of Egfr positive non small cell lung cancer and second the approval of launch of fire in inflammatory bowel disease or IBD, which follows the recent presentation of data. Once the superiority there shows the latter.

For me lives. You mentioned, we have made significant progress across our pipeline. Particular, I would like to highlight two major milestones on the horizon that will help drive sustained growth through 'twenty 'twenty five and beyond. First the approval of launch of <unk>, plus <unk> for first line treatment of Egfr positive non small cell lung cancer and second the approval of launch of fire in inflammatory bowel disease or IBD, which follows the recent presentation of data. Once the superiority there shows the latter.

You mentioned, we have made significant progress across our pipeline. Particular, I would like to highlight two major milestones on the horizon that will help drive sustained growth through 'twenty 'twenty five and beyond. First the approval of launch of <unk>, plus <unk> for first line treatment of Egfr positive non small cell lung cancer and second the approval of launch of fire in inflammatory bowel disease or IBD, which follows the recent presentation of data. Once the superiority there shows the latter.

Particular, I would like to highlight two major milestones on the horizon that will help drive sustained growth through 'twenty 'twenty five and beyond. First the approval of launch of <unk>, plus <unk> for first line treatment of Egfr positive non small cell lung cancer and second the approval of launch of fire in inflammatory bowel disease or IBD, which follows the recent presentation of data. Once the superiority there shows the latter.

First the approval of launch of <unk>, plus <unk> for first line treatment of Egfr positive non small cell lung cancer and second the approval of launch of fire in inflammatory bowel disease or IBD, which follows the recent presentation of data. Once the superiority there shows the latter.

Joaquin Duato: Once the superiority there shows the latter.

Joaquin Duato: This represents a meaningful opportunity for TREMFYA as approximately 75% of STELARA sales today come from IBD. We also have regulatory and data milestones for many of the assets that we expect to generate more than $5 billion in peak year sales. As the pipeline and portfolio progress, so too does our confidence in our near and long-term growth trajectory. We are confident in our ability to grow through the upcoming STELARA biosimilar entry and see accelerating momentum through the back half of the decade. In MedTech, year-to-date adjusted operational sales growth of 5.2% reflects continued progress with the portfolio as we move into higher growth markets. As you heard from Joe, we expect MedTech growth to accelerate in the second-half of the year. Growth will accelerate through continued expansion of new products, including ACUVUE OASYS Max 1-Day Contact Lenses, TECNIS Odyssey in the U.S., and VARIPULSE in Europe and Japan.

Approximately 75% of Este Lauder sales today come from IBD. We also have regulatory data milestones for many of the assets that we expect to generate more than $5 billion in peak year sales. I spent by buying a portfolio of progress so too does our confidence in our near and long term growth trajectory. We are confident in our ability to grow through the upcoming state lot of Biosimilar entry and see accelerating momentum through the back half of the decade. In Med Tech do year to date adjusted operational sales growth of five 2% reflects continued to progress with the portfolio as we move into higher growth markets. You'll hear from Joe we expect that growth to accelerate in the second half of midyear. Growth will accelerate through continued expansion of new products, including I keep you or he sees MX one day contact lenses pygmies all D. C. In the U S are multiples in Europe, and Japan,

We also have regulatory data milestones for many of the assets that we expect to generate more than $5 billion in peak year sales. I spent by buying a portfolio of progress so too does our confidence in our near and long term growth trajectory. We are confident in our ability to grow through the upcoming state lot of Biosimilar entry and see accelerating momentum through the back half of the decade. In Med Tech do year to date adjusted operational sales growth of five 2% reflects continued to progress with the portfolio as we move into higher growth markets. You'll hear from Joe we expect that growth to accelerate in the second half of midyear. Growth will accelerate through continued expansion of new products, including I keep you or he sees MX one day contact lenses pygmies all D. C. In the U S are multiples in Europe, and Japan,

I spent by buying a portfolio of progress so too does our confidence in our near and long term growth trajectory. We are confident in our ability to grow through the upcoming state lot of Biosimilar entry and see accelerating momentum through the back half of the decade. In Med Tech do year to date adjusted operational sales growth of five 2% reflects continued to progress with the portfolio as we move into higher growth markets. You'll hear from Joe we expect that growth to accelerate in the second half of midyear. Growth will accelerate through continued expansion of new products, including I keep you or he sees MX one day contact lenses pygmies all D. C. In the U S are multiples in Europe, and Japan,

We are confident in our ability to grow through the upcoming state lot of Biosimilar entry and see accelerating momentum through the back half of the decade. In Med Tech do year to date adjusted operational sales growth of five 2% reflects continued to progress with the portfolio as we move into higher growth markets. You'll hear from Joe we expect that growth to accelerate in the second half of midyear. Growth will accelerate through continued expansion of new products, including I keep you or he sees MX one day contact lenses pygmies all D. C. In the U S are multiples in Europe, and Japan,

In Med Tech do year to date adjusted operational sales growth of five 2% reflects continued to progress with the portfolio as we move into higher growth markets. You'll hear from Joe we expect that growth to accelerate in the second half of midyear. Growth will accelerate through continued expansion of new products, including I keep you or he sees MX one day contact lenses pygmies all D. C. In the U S are multiples in Europe, and Japan,

You'll hear from Joe we expect that growth to accelerate in the second half of midyear. Growth will accelerate through continued expansion of new products, including I keep you or he sees MX one day contact lenses pygmies all D. C. In the U S are multiples in Europe, and Japan,

Growth will accelerate through continued expansion of new products, including I keep you or he sees MX one day contact lenses pygmies all D. C. In the U S are multiples in Europe, and Japan, our confidence in the business outlook remains unchanged with meaningful outcome from the dangers sugar.

Growth will accelerate through continued expansion of new products, including I keep you or he sees MX one day contact lenses pygmies all D. C. In the U S are multiples in Europe, and Japan,

Joaquin Duato: Our confidence in the business outlook remains unchanged. With meaningful outcomes from the danger shock trial in Abiomed and the second quarter close of the Shockwave acquisition, we look forward to continue the expansion into high-growth MedTech markets. As you know, Johnson & Johnson is laser-focused on advancing the next wave of medical innovation. We are building on a strong foundation to unlock accelerated growth with a healthy balance sheet and industry-leading investments in the best science and innovation. This enables us to move into the second-half of 2024 from a position of strength. With that, let's open the line for questions.

Or are you not be humid on the second quarter close of the show wave I wish them. We look forward to continued expansion into high growth Med Tech markets. As you know Johnson and Johnson, who is laser focused on advancing the next wave of medical innovation. We're building on our strong foundation, who want to look accelerated growth with a healthy balance sheet and industry, leading investments in the best Science and innovation. It enables us to move into the second half of 'twenty 'twenty four from Apple She has shown strength. We've got let's open the line for questions.

As you know Johnson and Johnson, who is laser focused on advancing the next wave of medical innovation. We're building on our strong foundation, who want to look accelerated growth with a healthy balance sheet and industry, leading investments in the best Science and innovation. It enables us to move into the second half of 'twenty 'twenty four from Apple She has shown strength. We've got let's open the line for questions.

It enables us to move into the second half of 'twenty 'twenty four from Apple She has shown strength. We've got let's open the line for questions.

We've got let's open the line for questions.

Operator: Thank you. Ladies and gentlemen, if you like to ask a question at this time, please press star then one on your telephone keypad. If you'd like to withdraw your question, please press star then two. Please limit your questions to one question only. Our first question today is coming from Chris Schott from JP Morgan. Your line is now live.

Please limit your questions to one question only our first question today is coming from Chris Schott from JP Morgan. Your line is now live.

Chris Schott: Great. Thanks so much [inaudible] question. Maybe just a question on RYBREVANT. I know, Joaquin, you mentioned that as one of the key upcoming milestones for the company, but this does seem like a product where there's a disconnect between J&J's enthusiasm in the Street. So, maybe just enlighten us with some of the data we recently saw at ASCO on subcutaneous dosing, et cetera, the upcoming label expansion? Can you just talk about how you see RYBREVANT evolving overtime and your confidence that this product can take share in the frontline setting? Thank you.

And maybe just a question on on ride revert them when they walk in and you mentioned that as one of the key upcoming milestones for the company, but this does seem like a product where there's a disconnect between J&J enthusiasm in the street. What are some of the data recently so they have to go on the sub Q dosing et cetera. The upcoming label expansion you just talk about how you see wide reverb evolving overtime and your competence that this product can picture on the front line setting. Thank you.

What are some of the data recently so they have to go on the sub Q dosing et cetera. The upcoming label expansion you just talk about how you see wide reverb evolving overtime and your competence that this product can picture on the front line setting. Thank you.

Jennifer Taubert: Hi, Chris, it's Jennifer and thanks so much for the question. Real quick before I get into that one, I just wanted to give a quick shout-out to all my internal Innovative Medicine colleagues around the world for a terrific quarter. Our first $14 billion-plus quarter that we hit in over 10 products with double-digit growth. So, really, really a tremendous quarter and looking-forward to a great half of the year as well. So, we are very excited about RYBREVANT plus lazertinib and the data that we're seeing and really believe that it's going to have a significant place in frontline non-small cell lung cancer. As we've discussed before, there is a significant unmet need in frontline non-small cell lung cancer with about a quarter of patients never even making it to second-line therapy. So, a lot of patients that are there with high unmet medical need. When we take a look at the data that we've been able to generate in terms of PFS and when you add to that, the new data that we brought forward on our subcu dosing, we think together, we're going to have a really winning combination for patients in that frontline setting. So, high unmet need, really spectacular results that we're seeing and the subcu dosing we think is going to be a great combination.

Real quick before I get into that one I just wanted to give a quick shout out to all my internal innovative medicine colleagues around the world for a terrific quarter, our first 14 billion dollar plus quarter. That we had an over 10 products with double digit growth, so really really a tremendous quarter and looking forward to a great half of the year as well. So we are very excited about <unk> plus lizard Nab and the data that we're seeing and really believe that it's going to have a significant place in frontline <unk>. Small cell lung cancer as we've discussed before there's a significant unmet need in frontline non small cell lung cancer with about a quarter of patients never even making it to second line therapy. So a lot of patients that are are there with a high unmet medical need when we take a look. At the data that we've been able to generate in terms of PFS and when you add to that the new data that we brought forward on our sub Q dosing. We think together, we're going to have a really winning combination for patients in that frontline setting so high unmet need really spectacular results that we're seeing. And the sub Q dosing, we think is going to be a great combination.

That we had an over 10 products with double digit growth, so really really a tremendous quarter and looking forward to a great half of the year as well. So we are very excited about <unk> plus lizard Nab and the data that we're seeing and really believe that it's going to have a significant place in frontline <unk>. Small cell lung cancer as we've discussed before there's a significant unmet need in frontline non small cell lung cancer with about a quarter of patients never even making it to second line therapy. So a lot of patients that are are there with a high unmet medical need when we take a look. At the data that we've been able to generate in terms of PFS and when you add to that the new data that we brought forward on our sub Q dosing. We think together, we're going to have a really winning combination for patients in that frontline setting so high unmet need really spectacular results that we're seeing. And the sub Q dosing, we think is going to be a great combination.

Small cell lung cancer as we've discussed before there's a significant unmet need in frontline non small cell lung cancer with about a quarter of patients never even making it to second line therapy. So a lot of patients that are are there with a high unmet medical need when we take a look. At the data that we've been able to generate in terms of PFS and when you add to that the new data that we brought forward on our sub Q dosing. We think together, we're going to have a really winning combination for patients in that frontline setting so high unmet need really spectacular results that we're seeing. And the sub Q dosing, we think is going to be a great combination.

At the data that we've been able to generate in terms of PFS and when you add to that the new data that we brought forward on our sub Q dosing. We think together, we're going to have a really winning combination for patients in that frontline setting so high unmet need really spectacular results that we're seeing. And the sub Q dosing, we think is going to be a great combination.

And the sub Q dosing, we think is going to be a great combination.

Operator: Thank you. Next question is coming from Larry Biegelsen from Wells Fargo. Your line is now live.

Larry Biegelsen: Good morning. Thanks for taking the question. Tim, maybe we can do a deeper dive into MedTech. Just talk about what drove the reduction in the expected growth for MedTech in 2024? And how are you thinking about the Medtech end-markets in the second half and which J&J businesses do you see improving in the second-half and why? Thank you.

Maybe we can. Do a deeper dive into into med tech. Talk about what drove the reduction in the expected growth for med Tech in 'twenty, 'twenty, four and and how you're thinking about the med Tech end markets in the second half, which J&J businesses do you see improving in the second half and why thank you.

Do a deeper dive into into med tech. Talk about what drove the reduction in the expected growth for med Tech in 'twenty, 'twenty, four and and how you're thinking about the med Tech end markets in the second half, which J&J businesses do you see improving in the second half and why thank you.

Talk about what drove the reduction in the expected growth for med Tech in 'twenty, 'twenty, four and and how you're thinking about the med Tech end markets in the second half, which J&J businesses do you see improving in the second half and why thank you.

Tim Schmid: Larry, thank you for the question. Let me be very clear, we remain absolutely committed to delivering solid growth in the full-year for 2024. And Larry, when you actually look at ‘24 Q2, it was a tougher quarter for us. And we knew this, given the fact that at this time last year around the second quarter, we saw the opening up of the China market, which as you know is an important market for us and that was expected. That was actually by the way, last year our fastest-growing quarter. Now in all transparency, as you heard initially in the comments earlier, there have been two businesses that have or two areas of our business that have performed below expectations. Number one is Vision and secondly, our performance in China, which right now is a very volatile market. Now in Vision, we initially announced in the first quarter some challenges with distributor stocking dynamics here in the U.S., some competitive pressures, as well as some macroeconomic challenges in Japan.

And literally when you actually look at 'twenty for Q2, it was a tougher quarter for us and we knew this given the fact that at this time last year around the second quarter. We saw the opening up of the China market, which as you know is an important market for us and that was expected that was actually by the way last year. Our fastest growing quarter. Now in all transparency as you heard initially in the comments earlier, there had been two businesses that have or two areas of our business that have performed below expectations number one is vision. And secondly, outperformance in China, which right now is a very volatile market. Now envision we initially announced in the first quarter some challenges with the distributor stocking dynamics here in the U S from competitive pressures as well as some. Macroeconomic challenges in Japan,

Our fastest growing quarter. Now in all transparency as you heard initially in the comments earlier, there had been two businesses that have or two areas of our business that have performed below expectations number one is vision. And secondly, outperformance in China, which right now is a very volatile market. Now envision we initially announced in the first quarter some challenges with the distributor stocking dynamics here in the U S from competitive pressures as well as some. Macroeconomic challenges in Japan,

Now in all transparency as you heard initially in the comments earlier, there had been two businesses that have or two areas of our business that have performed below expectations number one is vision. And secondly, outperformance in China, which right now is a very volatile market. Now envision we initially announced in the first quarter some challenges with the distributor stocking dynamics here in the U S from competitive pressures as well as some. Macroeconomic challenges in Japan,

And secondly, outperformance in China, which right now is a very volatile market. Now envision we initially announced in the first quarter some challenges with the distributor stocking dynamics here in the U S from competitive pressures as well as some. Macroeconomic challenges in Japan,

Now envision we initially announced in the first quarter some challenges with the distributor stocking dynamics here in the U S from competitive pressures as well as some. Macroeconomic challenges in Japan,

Macroeconomic challenges in Japan, what gives me confidence in the turnaround of that business is that we actually saw sequential improvement through the second quarter. Some of those stocking dynamics dynamics I mentioned bled into April but month on month, we saw a strong rebound to that business in fact at the end of the quarter back to historical levels and so.

Macroeconomic challenges in Japan,

Tim Schmid: What gives me confidence in the turnaround of that business is that we actually saw sequential improvement through the second quarter. Some of those stocking dynamic dynamics I mentioned bled into April, but month-on-month, we saw strong rebound of that business, in fact, to the end of the quarter back to historical levels. And so as we look to the back half of the year, while it's been a slower start there, we're very confident that we're going to be able to bring that business back to historical norms, driven primarily by innovation. Our ACUVUE OASYS 1-Day MAX portfolio and that global launch as well as the addition of our premium IOLs with TECNIS PureSee in Asia-Pac and EMEA as well as Odyssey here in the U.S., and so we believe we've got that under control. When I look to the back half onto answer your question more directly, the reason we are confident is firstly, not only the return to more normalized growth within Vision, but in surgery, by the way, that--all that business also was impacted by a slower start, especially in China. We see that starting to normalize. And also remember in our surgery business, the results were impacted by the divestiture of a Acclarent last year. And so normalized growth--our adjusted operational growth was actually closer to flat. We see that continuing to grow at low-single-digit through the back half of the year. We're proud of the solid results in ortho and see that continuing to be driven by strong results within hip 6%, in knees, almost 10%, driven by tremendous innovation, especially in VELYS.

As we look to the back half of the year, while it's been a slow start there. We're very confident that we're going to be able to bring that business back to historical norms, driven primarily by innovation. This oasis, one day Macs portfolio and our global launch as well as the addition of our premium Io wells with some technical PRC in Asia Pac and EMEA as well as Odyssey here in the U S and so we believe we've got that under control when I look to the back half to answer your question more directly the reasons. We are confident his first day not only the. It returned to more normalized growth within envision but in surgery by the way that all of that business also was impacted. By a slower start, especially in China, we see that starting to normalize and also remember in our surgery business. The results were impacted by the divestiture of our clearance last year and so normalized growth in our adjusted operational growth was actually closer to flat, we see that continuing to grow at low single digits through the back half of the year. Loud of our solid results and also and see that continuing to be driven by strong results within hip 6% in knees almost 10% driven. Driven by tremendous innovation, especially in Venice,

This oasis, one day Macs portfolio and our global launch as well as the addition of our premium Io wells with some technical PRC in Asia Pac and EMEA as well as Odyssey here in the U S and so we believe we've got that under control when I look to the back half to answer your question more directly the reasons. We are confident his first day not only the. It returned to more normalized growth within envision but in surgery by the way that all of that business also was impacted. By a slower start, especially in China, we see that starting to normalize and also remember in our surgery business. The results were impacted by the divestiture of our clearance last year and so normalized growth in our adjusted operational growth was actually closer to flat, we see that continuing to grow at low single digits through the back half of the year. Loud of our solid results and also and see that continuing to be driven by strong results within hip 6% in knees almost 10% driven. Driven by tremendous innovation, especially in Venice,

It returned to more normalized growth within envision but in surgery by the way that all of that business also was impacted. By a slower start, especially in China, we see that starting to normalize and also remember in our surgery business. The results were impacted by the divestiture of our clearance last year and so normalized growth in our adjusted operational growth was actually closer to flat, we see that continuing to grow at low single digits through the back half of the year. Loud of our solid results and also and see that continuing to be driven by strong results within hip 6% in knees almost 10% driven. Driven by tremendous innovation, especially in Venice,

By a slower start, especially in China, we see that starting to normalize and also remember in our surgery business. The results were impacted by the divestiture of our clearance last year and so normalized growth in our adjusted operational growth was actually closer to flat, we see that continuing to grow at low single digits through the back half of the year. Loud of our solid results and also and see that continuing to be driven by strong results within hip 6% in knees almost 10% driven. Driven by tremendous innovation, especially in Venice,

Loud of our solid results and also and see that continuing to be driven by strong results within hip 6% in knees almost 10% driven. Driven by tremendous innovation, especially in Venice,

Driven by tremendous innovation, especially in Venice, and then more broadly I'll end with our real confidence in the growth of our cardiovascular portfolio remember Larry that we've got on the EP business. That's $5 billion today grew 21% last year and 19% for the first half of the year in fact in the second quarter in the face of.

Driven by tremendous innovation, especially in Venice,

Tim Schmid: And then more broadly, I'll end with our real confidence in the growth of our cardiovascular portfolio. And remember, Larry, that we've got an EP business that's $5 billion today, grew 21% last year, 19% for the first-half of the year. In fact, in the second quarter, in the face of competition, here in the U.S. we grew that business 16%. And so we're very confident in our ability to grow that leadership position. And then finally, the addition of Abiomed still continuing to grow ahead of our deal expectations, 15.4%. I think that's going to be bolstered by the landmark results, the first time in 25 years, where we have the DanGer Shock study showing survivability benefits of Impella, which will continue to open new markets for that portfolio. And then finally, I'll end with how delighted we are to inch very, very short order, welcome Shockwave to Johnson & Johnson. We closed that transaction in record timing and are really excited by the fact that we will shortly announce that they will be the 13th business with sales in excess of $1 billion annually. And so for all those reasons, Larry, while a tougher second year--second quarter primarily due to comps, we remain very confident in a solid 2024.

Sure in the U S. We grew that because it was 16% and so we're very confident in our ability to grow that leadership position and then finally, the addition of the Abu Ahmed still continuing to grow ahead of our deal expectations 15 for 15, 4% I think that's gonna be bolstered by the landmark results of the first time in 25 years. Have the danger shock study showing survivability benefits of Impella, which will continue to open new markets for that portfolio and then finally I'll end with how delighted we are to inch very very short order well come Shockwave to Johnson <unk> Johnson, who we closed that that transaction in and record timing and are really. Excited by the fact that we will shortly announce that they will be the 13th business with sales in excess of $1 billion annually and so for all those reasons, Larry Lala, while our top or second gear second quarter, primarily due to comps we remain very confident in a solid 2024.

Have the danger shock study showing survivability benefits of Impella, which will continue to open new markets for that portfolio and then finally I'll end with how delighted we are to inch very very short order well come Shockwave to Johnson <unk> Johnson, who we closed that that transaction in and record timing and are really. Excited by the fact that we will shortly announce that they will be the 13th business with sales in excess of $1 billion annually and so for all those reasons, Larry Lala, while our top or second gear second quarter, primarily due to comps we remain very confident in a solid 2024.

Excited by the fact that we will shortly announce that they will be the 13th business with sales in excess of $1 billion annually and so for all those reasons, Larry Lala, while our top or second gear second quarter, primarily due to comps we remain very confident in a solid 2024.

Operator: Thank you. Our next question is coming from Louise Chen from Cantor Fitzgerald. Your line is now live.

Louise Chen: Hi, thank you for taking my question. Wanted to ask you about your Phase III nipocalimab data that you presented recently. And how do you compare and contrast the efficacy and durability of your product versus other FCRNs and mechanisms of actions on the market? Thank you.

John C. Reed: Yes, John Reed here. Thanks for that question. Well, we're really excited about the data in Sjogren's with nipocalimab. It's the data we delivered shows really sustained disease control, which is so important by our dosing regimen as compared to some of the intermittent dosing regimens used by others. And the consistent efficacy we've seen across all primary, secondary endpoints, et cetera is really compelling as a guess that we may be on the first advanced therapy for Sjogren's that disease has ever seen. As you know, that's a very prevalent disorder affecting its estimated 4 million people around the world, perhaps 1 million in the United States, 90% of the people impacted are women right in the prime of life. So, we're really excited about the possibility of bringing forward the first advanced therapy for that disorder.

The data we've delivered show. Really sustained disease control, which is so important. By our dosing regimen. To some of the intermittent dosing regimens used by others. And the. The. Consistent efficacy. Efficacy, we've seen across all primary and secondary endpoints et cetera, who is really compelling. So we may be on the first advanced therapy for our showrooms that are that diseases ever ever seen if you go. That's a very prevalent disorder affecting its estimated 4 million people around the world, perhaps familiar United States. 90% of the people impacted are women right in the prime of life. So we're really excited about the possibility of bringing forward the first therapy for that disorder.

Really sustained disease control, which is so important. By our dosing regimen. To some of the intermittent dosing regimens used by others. And the. The. Consistent efficacy. Efficacy, we've seen across all primary and secondary endpoints et cetera, who is really compelling. So we may be on the first advanced therapy for our showrooms that are that diseases ever ever seen if you go. That's a very prevalent disorder affecting its estimated 4 million people around the world, perhaps familiar United States. 90% of the people impacted are women right in the prime of life. So we're really excited about the possibility of bringing forward the first therapy for that disorder.

By our dosing regimen. To some of the intermittent dosing regimens used by others. And the. The. Consistent efficacy. Efficacy, we've seen across all primary and secondary endpoints et cetera, who is really compelling. So we may be on the first advanced therapy for our showrooms that are that diseases ever ever seen if you go. That's a very prevalent disorder affecting its estimated 4 million people around the world, perhaps familiar United States. 90% of the people impacted are women right in the prime of life. So we're really excited about the possibility of bringing forward the first therapy for that disorder.

To some of the intermittent dosing regimens used by others. And the. The. Consistent efficacy. Efficacy, we've seen across all primary and secondary endpoints et cetera, who is really compelling. So we may be on the first advanced therapy for our showrooms that are that diseases ever ever seen if you go. That's a very prevalent disorder affecting its estimated 4 million people around the world, perhaps familiar United States. 90% of the people impacted are women right in the prime of life. So we're really excited about the possibility of bringing forward the first therapy for that disorder.

And the. The. Consistent efficacy. Efficacy, we've seen across all primary and secondary endpoints et cetera, who is really compelling. So we may be on the first advanced therapy for our showrooms that are that diseases ever ever seen if you go. That's a very prevalent disorder affecting its estimated 4 million people around the world, perhaps familiar United States. 90% of the people impacted are women right in the prime of life. So we're really excited about the possibility of bringing forward the first therapy for that disorder.

The. Consistent efficacy. Efficacy, we've seen across all primary and secondary endpoints et cetera, who is really compelling. So we may be on the first advanced therapy for our showrooms that are that diseases ever ever seen if you go. That's a very prevalent disorder affecting its estimated 4 million people around the world, perhaps familiar United States. 90% of the people impacted are women right in the prime of life. So we're really excited about the possibility of bringing forward the first therapy for that disorder.

Consistent efficacy. Efficacy, we've seen across all primary and secondary endpoints et cetera, who is really compelling. So we may be on the first advanced therapy for our showrooms that are that diseases ever ever seen if you go. That's a very prevalent disorder affecting its estimated 4 million people around the world, perhaps familiar United States. 90% of the people impacted are women right in the prime of life. So we're really excited about the possibility of bringing forward the first therapy for that disorder.

Efficacy, we've seen across all primary and secondary endpoints et cetera, who is really compelling. So we may be on the first advanced therapy for our showrooms that are that diseases ever ever seen if you go. That's a very prevalent disorder affecting its estimated 4 million people around the world, perhaps familiar United States. 90% of the people impacted are women right in the prime of life. So we're really excited about the possibility of bringing forward the first therapy for that disorder.

So we may be on the first advanced therapy for our showrooms that are that diseases ever ever seen if you go. That's a very prevalent disorder affecting its estimated 4 million people around the world, perhaps familiar United States. 90% of the people impacted are women right in the prime of life. So we're really excited about the possibility of bringing forward the first therapy for that disorder.

That's a very prevalent disorder affecting its estimated 4 million people around the world, perhaps familiar United States. 90% of the people impacted are women right in the prime of life. So we're really excited about the possibility of bringing forward the first therapy for that disorder.

90% of the people impacted are women right in the prime of life. So we're really excited about the possibility of bringing forward the first therapy for that disorder.

Jessica Moore: Maybe I can add-in a couple of things on as well because we're really excited by what we're seeing from all the data that's coming out. And over the last 18 months, we've demonstrated clinical effect in actually four auto-antibody driven diseases and we are the only FCRN blocker that's in development where we've got proof-of-concept in all three segments of auto-antibody driven diseases from rare auto-antibody to prevalent room to maternal fetal. So as we take a look at all the data that's coming forward as we're bringing this to market, we are even more confident--in terms of confidence that this is a $5 billion-plus asset for us.

And all three segments of auto antibody driven diseases from rare auto antibody too prevalent room to maternal fetal so as we take a look at all the data that's coming forward on as we're bringing this to market. We are even more convinced today and that's in terms of confidence that this is a $5 billion plus asset for us.

Operator: Thank you. Our next question today is coming from Rick Wise from Stifel. Your line is now live.

Rick Wise: Good morning, everybody. If I could talk a little bit about the EP business. Obviously, this is the first full quarter where we're really seeing a broader launch of a competitive PFA system. You updated us on your system. But maybe if you could give us more color broadly on the impact you're seeing on EP growth and the outlook for the second-half, and help us better understand how this launch and the lot of CARTO 3 version 8 launch is being affected here. I’m assuming mapping growth was strong, but maybe--I don't know, maybe the catheter business was pressured by the competitive system. Can you help give us that macro color and maybe the specific impact on Biosense Webster. Thank you.

If I could talk a little bit about the E&P business. And obviously this is the first. Full quarter, we're really seeing. A broader launch of our competitive PFA system, you update us on. Your system, but maybe if you could give us more color broadly. On the impact Youre seeing. On the EPS growth and the outlook for the second half and help us better understand how this launch and the launch of Cardona three version eight launch. Is. Being affected here I'm, assuming mapping growth was strong. Maybe I don't know maybe the catheter business was pressured by the competitive system can you help give us that macro color and maybe. Specific impact on our Biosense Webster. Thank you.

And obviously this is the first. Full quarter, we're really seeing. A broader launch of our competitive PFA system, you update us on. Your system, but maybe if you could give us more color broadly. On the impact Youre seeing. On the EPS growth and the outlook for the second half and help us better understand how this launch and the launch of Cardona three version eight launch. Is. Being affected here I'm, assuming mapping growth was strong. Maybe I don't know maybe the catheter business was pressured by the competitive system can you help give us that macro color and maybe. Specific impact on our Biosense Webster. Thank you.

Full quarter, we're really seeing. A broader launch of our competitive PFA system, you update us on. Your system, but maybe if you could give us more color broadly. On the impact Youre seeing. On the EPS growth and the outlook for the second half and help us better understand how this launch and the launch of Cardona three version eight launch. Is. Being affected here I'm, assuming mapping growth was strong. Maybe I don't know maybe the catheter business was pressured by the competitive system can you help give us that macro color and maybe. Specific impact on our Biosense Webster. Thank you.

A broader launch of our competitive PFA system, you update us on. Your system, but maybe if you could give us more color broadly. On the impact Youre seeing. On the EPS growth and the outlook for the second half and help us better understand how this launch and the launch of Cardona three version eight launch. Is. Being affected here I'm, assuming mapping growth was strong. Maybe I don't know maybe the catheter business was pressured by the competitive system can you help give us that macro color and maybe. Specific impact on our Biosense Webster. Thank you.

Your system, but maybe if you could give us more color broadly. On the impact Youre seeing. On the EPS growth and the outlook for the second half and help us better understand how this launch and the launch of Cardona three version eight launch. Is. Being affected here I'm, assuming mapping growth was strong. Maybe I don't know maybe the catheter business was pressured by the competitive system can you help give us that macro color and maybe. Specific impact on our Biosense Webster. Thank you.

On the impact Youre seeing. On the EPS growth and the outlook for the second half and help us better understand how this launch and the launch of Cardona three version eight launch. Is. Being affected here I'm, assuming mapping growth was strong. Maybe I don't know maybe the catheter business was pressured by the competitive system can you help give us that macro color and maybe. Specific impact on our Biosense Webster. Thank you.

On the EPS growth and the outlook for the second half and help us better understand how this launch and the launch of Cardona three version eight launch. Is. Being affected here I'm, assuming mapping growth was strong. Maybe I don't know maybe the catheter business was pressured by the competitive system can you help give us that macro color and maybe. Specific impact on our Biosense Webster. Thank you.

Is. Being affected here I'm, assuming mapping growth was strong. Maybe I don't know maybe the catheter business was pressured by the competitive system can you help give us that macro color and maybe. Specific impact on our Biosense Webster. Thank you.

Being affected here I'm, assuming mapping growth was strong. Maybe I don't know maybe the catheter business was pressured by the competitive system can you help give us that macro color and maybe. Specific impact on our Biosense Webster. Thank you.

Maybe I don't know maybe the catheter business was pressured by the competitive system can you help give us that macro color and maybe. Specific impact on our Biosense Webster. Thank you.

Specific impact on our Biosense Webster. Thank you.

Tim Schmid: Of course, Rick and thank you for the question. And Rick, I'd start with firstly, recognizing that we believe that PFA is really good for electrophysiology and really good for patients. It is a tailwind for the entire market. And as I mentioned earlier, that's a $5 billion market for us today, growing 19% year-to-date. And let me be clear, we clearly see some competition, especially here in the U.S., especially between now and the time that we bring our PFA technology to market, we're confident. While we don't control the timing, we expect to have that by the end of the year or early next year. As you know, we already have and are commercializing our PFA technology in EMEA and in Japan, and we are very fortunate to actually benefit from a very global EP business. What gives us confidence in the future, Larry, is that we believe that while PFA has a role to play in the portfolio, so does RF. From everything we're hearing from EPs around the world, what they like about PFA is the relative safety of the technology, but they also like about RF, which by the way, we have 20-years of leadership in safety and clinical efficacy, is the durability of that product. In fact, even today, Rick, here in the U.S., for every five procedures where PFA is used, RF is used in conjunction.

Let's start with. Firstly, recognizing that we believe that PSA is really good for electrophysiology and really good for patients. It is a tailwind for the entire market and as I mentioned earlier, that's a $5 billion market for us today growing 19% year to date. And let me, let me be clear, we clearly see some competition, especially here in the U S. You know, especially between now and the time that we bring a PFA technology to market. We're confident while we don't control. The timings, we expect to have that by the end of the year or early next year. As you know we already have approval and are commercializing our Psa. G in EMEA and in Japan, and we are very fortunate to actually benefit from a very global E&P business. What gives us confidence in the future Larry is that we believe that while PSA has a role to play in the portfolio. So does RF from everything we're hearing from <unk> around the world what they like about PSA is the relative safety of the technology, but they also like about RF, which by the way we have 20 years of leadership in safety and clinical efficacy. C is the durability of that product in fact, even today Rick here in the U S. For every five procedures, where PFA is used RF is used in conjunction

Firstly, recognizing that we believe that PSA is really good for electrophysiology and really good for patients. It is a tailwind for the entire market and as I mentioned earlier, that's a $5 billion market for us today growing 19% year to date. And let me, let me be clear, we clearly see some competition, especially here in the U S. You know, especially between now and the time that we bring a PFA technology to market. We're confident while we don't control. The timings, we expect to have that by the end of the year or early next year. As you know we already have approval and are commercializing our Psa. G in EMEA and in Japan, and we are very fortunate to actually benefit from a very global E&P business. What gives us confidence in the future Larry is that we believe that while PSA has a role to play in the portfolio. So does RF from everything we're hearing from <unk> around the world what they like about PSA is the relative safety of the technology, but they also like about RF, which by the way we have 20 years of leadership in safety and clinical efficacy. C is the durability of that product in fact, even today Rick here in the U S. For every five procedures, where PFA is used RF is used in conjunction

And let me, let me be clear, we clearly see some competition, especially here in the U S. You know, especially between now and the time that we bring a PFA technology to market. We're confident while we don't control. The timings, we expect to have that by the end of the year or early next year. As you know we already have approval and are commercializing our Psa. G in EMEA and in Japan, and we are very fortunate to actually benefit from a very global E&P business. What gives us confidence in the future Larry is that we believe that while PSA has a role to play in the portfolio. So does RF from everything we're hearing from <unk> around the world what they like about PSA is the relative safety of the technology, but they also like about RF, which by the way we have 20 years of leadership in safety and clinical efficacy. C is the durability of that product in fact, even today Rick here in the U S. For every five procedures, where PFA is used RF is used in conjunction

G in EMEA and in Japan, and we are very fortunate to actually benefit from a very global E&P business. What gives us confidence in the future Larry is that we believe that while PSA has a role to play in the portfolio. So does RF from everything we're hearing from <unk> around the world what they like about PSA is the relative safety of the technology, but they also like about RF, which by the way we have 20 years of leadership in safety and clinical efficacy. C is the durability of that product in fact, even today Rick here in the U S. For every five procedures, where PFA is used RF is used in conjunction

What gives us confidence in the future Larry is that we believe that while PSA has a role to play in the portfolio. So does RF from everything we're hearing from <unk> around the world what they like about PSA is the relative safety of the technology, but they also like about RF, which by the way we have 20 years of leadership in safety and clinical efficacy. C is the durability of that product in fact, even today Rick here in the U S. For every five procedures, where PFA is used RF is used in conjunction

C is the durability of that product in fact, even today Rick here in the U S. For every five procedures, where PFA is used RF is used in conjunction and so we believe that leadership position that we built over the last 20 years will continue both in RF and then obviously we're excited by.

C is the durability of that product in fact, even today Rick here in the U S. For every five procedures, where PFA is used RF is used in conjunction

Tim Schmid: And so, we believe that leisure position that we built over the last 20-years will continue, both in RF and then obviously, we're excited by the launch of our PFA technology. You'll know that at the HRS conference in May, we announced the results of our admIRE study, which showed the 86% relative effectiveness--primary effectiveness of our PFA technology. And we are going to continue to employ the same strategy we did in RF, which is building out a broad portfolio of PFA offerings, both in dual energy, focal, large focal and single shot. Did you know that today, the number one used catheter on the market is our SPF catheter within RF. And we are--and you'll know that in the second--first quarter of this year, we announced a application for a CE mark for our dual energy catheter. This will be one catheter used, both for RF and PFA technology. And so, we've got a lot of reasons to believe. And I think to touch on your point on CARTO, one of the benefit of our portfolios, not just our energy source and catheters, it really is the installed base of 5,500 CARTO systems around the world. We just version 8 of that software. It is best-in-class in the market. And that's also complemented by highly trained clinical specialists in every cath lab around the world who are supporting EPs each and every day. And so once again, PFA is a good thing for the marketplace, it's a tailwind and we expect to continue to benefit on that. Thank you.

The launch of our PSA technology, you'll know that at the HRS conference. In May we announced the results of our admire study, which showed the 86% relative effectiveness our primary effectiveness all the RP assay technology. And we're going to continue to employ the same strategy. We did in RF, which is building out a broad portfolio of PFA offerings, both in dual energy focal large focal and single shot. You know that today the number one used a catheter on the market is our S. P. F <unk> catheter with in RF, and we are and you'll know that in the second and first quarter of this year, we announced them. Application for a CE mark for our dual energy catheter. This will be one catheter used those for RF and PSA technology and so we got a lot of reasons to believe and I think to touch on your point on car two one of the benefits all of our portfolio is not just our energy source and catheter or is it really is the end. The old base of 5500 cargo systems around the World. We just launched our version eight of that software. It has best in class in the market and that's also complemented by a highly trained clinical specialists in every cath lab around the world who are supporting EPS, each and every day and so you know what. Once again PFA is a good thing for the marketplace. It's a tailwind and we expect to continue to benefit on that thank you.

In May we announced the results of our admire study, which showed the 86% relative effectiveness our primary effectiveness all the RP assay technology. And we're going to continue to employ the same strategy. We did in RF, which is building out a broad portfolio of PFA offerings, both in dual energy focal large focal and single shot. You know that today the number one used a catheter on the market is our S. P. F <unk> catheter with in RF, and we are and you'll know that in the second and first quarter of this year, we announced them. Application for a CE mark for our dual energy catheter. This will be one catheter used those for RF and PSA technology and so we got a lot of reasons to believe and I think to touch on your point on car two one of the benefits all of our portfolio is not just our energy source and catheter or is it really is the end. The old base of 5500 cargo systems around the World. We just launched our version eight of that software. It has best in class in the market and that's also complemented by a highly trained clinical specialists in every cath lab around the world who are supporting EPS, each and every day and so you know what. Once again PFA is a good thing for the marketplace. It's a tailwind and we expect to continue to benefit on that thank you.

And we're going to continue to employ the same strategy. We did in RF, which is building out a broad portfolio of PFA offerings, both in dual energy focal large focal and single shot. You know that today the number one used a catheter on the market is our S. P. F <unk> catheter with in RF, and we are and you'll know that in the second and first quarter of this year, we announced them. Application for a CE mark for our dual energy catheter. This will be one catheter used those for RF and PSA technology and so we got a lot of reasons to believe and I think to touch on your point on car two one of the benefits all of our portfolio is not just our energy source and catheter or is it really is the end. The old base of 5500 cargo systems around the World. We just launched our version eight of that software. It has best in class in the market and that's also complemented by a highly trained clinical specialists in every cath lab around the world who are supporting EPS, each and every day and so you know what. Once again PFA is a good thing for the marketplace. It's a tailwind and we expect to continue to benefit on that thank you.

You know that today the number one used a catheter on the market is our S. P. F <unk> catheter with in RF, and we are and you'll know that in the second and first quarter of this year, we announced them. Application for a CE mark for our dual energy catheter. This will be one catheter used those for RF and PSA technology and so we got a lot of reasons to believe and I think to touch on your point on car two one of the benefits all of our portfolio is not just our energy source and catheter or is it really is the end. The old base of 5500 cargo systems around the World. We just launched our version eight of that software. It has best in class in the market and that's also complemented by a highly trained clinical specialists in every cath lab around the world who are supporting EPS, each and every day and so you know what. Once again PFA is a good thing for the marketplace. It's a tailwind and we expect to continue to benefit on that thank you.

Application for a CE mark for our dual energy catheter. This will be one catheter used those for RF and PSA technology and so we got a lot of reasons to believe and I think to touch on your point on car two one of the benefits all of our portfolio is not just our energy source and catheter or is it really is the end. The old base of 5500 cargo systems around the World. We just launched our version eight of that software. It has best in class in the market and that's also complemented by a highly trained clinical specialists in every cath lab around the world who are supporting EPS, each and every day and so you know what. Once again PFA is a good thing for the marketplace. It's a tailwind and we expect to continue to benefit on that thank you.

The old base of 5500 cargo systems around the World. We just launched our version eight of that software. It has best in class in the market and that's also complemented by a highly trained clinical specialists in every cath lab around the world who are supporting EPS, each and every day and so you know what. Once again PFA is a good thing for the marketplace. It's a tailwind and we expect to continue to benefit on that thank you.

Once again PFA is a good thing for the marketplace. It's a tailwind and we expect to continue to benefit on that thank you.

Operator: Thank you. The next question is coming from Terence Flynn from Morgan Stanley. Your line is now live.

Terence C. Flynn: Great. Thanks for taking the question. Two parts for me on IRA. Was just wondering if you can offer any perspective on the impact of IRA negotiation STELARA and XARELTO as we're getting close to the disclosure of the pricing decision? And then also Part D redesign in 2025, just some high-level thoughts? And the second part of the question relates to your confidence that DARZALEX FASPRO will be looked at separately than DARZALEX just given the Hyaluronidase component there. Thank you.

And the second part of the question relates to your confidence that doors like fast pro will be looked at separately than ours, who works just given the pilar on today's component there. Thank you.

Jennifer Taubert: Thanks so much for the question. I'll answer the second part first. We do have very good confidence that DARZALEX FASPRO is treated separately than DARZALEX IV. And so yes, we continue forward with that strong perspective on that. In terms of IRA and kind of what's been going on, if we take a look at Part D redesign, while we're not externally quantifying the impact at this time, what we can say is that we do anticipate a net unfavorable impact in 2025. However, as outlined at our enterprise business review last November, we do anticipate, as a business, growing 3% plus next year and then 5% to 7% out through 2030. And these numbers are actually already included in that guidance that we provided. Same thing as it pertains to the government price setting process, we are still in that. We have received the final numbers from the government, we're not disclosing that at this time. That will be disclosed in the September time frame. And while we are not in alignment with IRA and the price setting process, those numbers have been included in the guidance that we provided last year at EBR, that still looks very good to us today. It's very consistent today.

Thanks, So much for the question and maybe I'll answer the second part first we do have very good confidence that doors elect SaaS probe is treated separately than dogs, who likes the IV and so yeah. We continue forward. With that strong perspective on that in terms of I R. A and kind of what's been going on if we take a look at part D redesign well, we're not externally quantifying the impact at this time on what we can say is that we do anticipate a net unfavorable impact in 2025. However. As outlined at our Enterprise business review last November. We do anticipate as a business growing 3% plus next year, and then 5% to 7% out through them out through 2030 and these numbers are actually already included in that guidance that we've provided same thing as it pertains to the government price setting process, we are still in that. We have received the final. Numbers from the government, we're not disclosing that at this time that'll be disclosed in the September timeframe and well you know we are not in alignment with Io array and the price setting process and those numbers have been included in the guidance that we provided last year at E. B R. That's still looks very good to us today. Very consistent today.

With that strong perspective on that in terms of I R. A and kind of what's been going on if we take a look at part D redesign well, we're not externally quantifying the impact at this time on what we can say is that we do anticipate a net unfavorable impact in 2025. However. As outlined at our Enterprise business review last November. We do anticipate as a business growing 3% plus next year, and then 5% to 7% out through them out through 2030 and these numbers are actually already included in that guidance that we've provided same thing as it pertains to the government price setting process, we are still in that. We have received the final. Numbers from the government, we're not disclosing that at this time that'll be disclosed in the September timeframe and well you know we are not in alignment with Io array and the price setting process and those numbers have been included in the guidance that we provided last year at E. B R. That's still looks very good to us today. Very consistent today.

As outlined at our Enterprise business review last November. We do anticipate as a business growing 3% plus next year, and then 5% to 7% out through them out through 2030 and these numbers are actually already included in that guidance that we've provided same thing as it pertains to the government price setting process, we are still in that. We have received the final. Numbers from the government, we're not disclosing that at this time that'll be disclosed in the September timeframe and well you know we are not in alignment with Io array and the price setting process and those numbers have been included in the guidance that we provided last year at E. B R. That's still looks very good to us today. Very consistent today.

We do anticipate as a business growing 3% plus next year, and then 5% to 7% out through them out through 2030 and these numbers are actually already included in that guidance that we've provided same thing as it pertains to the government price setting process, we are still in that. We have received the final. Numbers from the government, we're not disclosing that at this time that'll be disclosed in the September timeframe and well you know we are not in alignment with Io array and the price setting process and those numbers have been included in the guidance that we provided last year at E. B R. That's still looks very good to us today. Very consistent today.

We have received the final. Numbers from the government, we're not disclosing that at this time that'll be disclosed in the September timeframe and well you know we are not in alignment with Io array and the price setting process and those numbers have been included in the guidance that we provided last year at E. B R. That's still looks very good to us today. Very consistent today.

Numbers from the government, we're not disclosing that at this time that'll be disclosed in the September timeframe and well you know we are not in alignment with Io array and the price setting process and those numbers have been included in the guidance that we provided last year at E. B R. That's still looks very good to us today. Very consistent today.

Very consistent today.

John C. Reed: Since you mentioned, DARZALEX. John Reed here, I thought maybe I would just remind you that actually, in this quarter, we delivered four additional positive Phase III studies with DARZALEX across a number of indications, including transplant ineligible frontline, including in the maintenance setting, after transplant, including smoldering condition that is as large as the entirety of diagnostically defying myeloma and in amyloidosis. So, the momentum continues with DARZALEX.

Speaker Change: Remind you that actually in this quarter, we delivered four additional positive phase III studies with doors, who works across a number of indications, including transplant ineligible frontline, including in the maintenance setting after transplant. Loading smoldering condition that is as large as the entirety of diagnostic redeploy myeloma and an amyloidosis. So the momentum continues with ours alerts.

Loading smoldering condition that is as large as the entirety of diagnostic redeploy myeloma and an amyloidosis. So the momentum continues with ours alerts.

Jennifer Taubert: And we had 21% growth. $2.9 billion in sales and 21% growth. So yes, DARZALEX is our single largest asset now for the corporation.

<unk> is our single largest asset now for the Corporation.

Operator: Thank you. Our next question is coming from Josh Jennings from TD Cowen. Your line is now live.

Joshua Jennings: Hi, good morning. Thanks for taking the questions. I was hoping to just touch on MedTech and outlook for procedure volume trends in the back half. There have been some concerns that there's some tough comps on the utilization side and particularly for the orthopedic sector. But I was hoping to just hear your outlook in how that's blended into this acceleration in the half? And then maybe also, if you could just touch on the pricing environment and your outlook for device pricing and where pricing stands for the MedTech portfolio? Thanks for taking the question.

If there's some tough comps on the utilization side and particularly for. For the orthopedic sector, but I was hoping to just hear your outlook and how that's blended into the this the acceleration in the back half and then maybe also if you could just touch on the pricing environment and your outlook for device pricing and where pricing stands for the med Tech portfolio. Thanks for taking the question.

For the orthopedic sector, but I was hoping to just hear your outlook and how that's blended into the this the acceleration in the back half and then maybe also if you could just touch on the pricing environment and your outlook for device pricing and where pricing stands for the med Tech portfolio. Thanks for taking the question.

Joseph J. Wolk: Sure, Josh. And I think my answer to your sort of volume question will be very brief and consistent with what we've shared before. For the most part, across the portfolio, we've seen volumes normalize. We did mention that we expected to see some of the--some tailwinds from the backlog within Orthopedics in the first-half of the year. And we've seen that, but we expect that to normalize in the back half. We remain consistent in our belief in the 5% to 7% growth for our end markets and that we will perform well within that. As it relates to pricing, inflation has not been a friend to our industry, and we have put a lot of effort into really ensuring that we can secure preferential pricing across the world. I do think we benefit from the global nature of our business. While there are pockets cost containment efforts that we're managing, like VBP in China, we see tremendous opportunity to really secure a premium pricing, especially where we have differentiated innovation. And especially now that we're entering areas like cardiovascular of significant unmet need, there is tremendous opportunities for us to ensure that we secure premium pricing for truly differentiated innovations, especially in areas like electrophysiology, in heart recovery with Abiomed, and more recently with Shockwave. Thank you.

Volumes normalize. We did mention that we expected to see some. All of the somebody some tailwind from the backlog within orthopedics and the first half of the and we've seen that who we expect that to normalize in the back half we remain consistent in our belief in the 5% to 7% growth for our end markets and that we will but we will we will perform well within that. As it relates to pricing you know inflation is not being a friend who are industry and we have put a lot of effort into really ensuring that we can secure a preferential preferential trade pricing across the world I do think we benefit from the global nature of our business. While there are pockets of cost containment efforts that were managing like V. P. In China are we. See tremendous opportunity to really secure a premium pricing, especially where we have differentiated innovation and especially now that we entering are entering. Areas like cardiovascular vascular a significant unmet need. There's tremendous opportunities for us to ensure that we secure a premium pricing for truly differentiated innovations, especially in areas like electrophysiology. Heart recovery with Abbvie Ahmed and more recently with Shockwave. Thank you.

We did mention that we expected to see some. All of the somebody some tailwind from the backlog within orthopedics and the first half of the and we've seen that who we expect that to normalize in the back half we remain consistent in our belief in the 5% to 7% growth for our end markets and that we will but we will we will perform well within that. As it relates to pricing you know inflation is not being a friend who are industry and we have put a lot of effort into really ensuring that we can secure a preferential preferential trade pricing across the world I do think we benefit from the global nature of our business. While there are pockets of cost containment efforts that were managing like V. P. In China are we. See tremendous opportunity to really secure a premium pricing, especially where we have differentiated innovation and especially now that we entering are entering. Areas like cardiovascular vascular a significant unmet need. There's tremendous opportunities for us to ensure that we secure a premium pricing for truly differentiated innovations, especially in areas like electrophysiology. Heart recovery with Abbvie Ahmed and more recently with Shockwave. Thank you.

All of the somebody some tailwind from the backlog within orthopedics and the first half of the and we've seen that who we expect that to normalize in the back half we remain consistent in our belief in the 5% to 7% growth for our end markets and that we will but we will we will perform well within that. As it relates to pricing you know inflation is not being a friend who are industry and we have put a lot of effort into really ensuring that we can secure a preferential preferential trade pricing across the world I do think we benefit from the global nature of our business. While there are pockets of cost containment efforts that were managing like V. P. In China are we. See tremendous opportunity to really secure a premium pricing, especially where we have differentiated innovation and especially now that we entering are entering. Areas like cardiovascular vascular a significant unmet need. There's tremendous opportunities for us to ensure that we secure a premium pricing for truly differentiated innovations, especially in areas like electrophysiology. Heart recovery with Abbvie Ahmed and more recently with Shockwave. Thank you.

As it relates to pricing you know inflation is not being a friend who are industry and we have put a lot of effort into really ensuring that we can secure a preferential preferential trade pricing across the world I do think we benefit from the global nature of our business. While there are pockets of cost containment efforts that were managing like V. P. In China are we. See tremendous opportunity to really secure a premium pricing, especially where we have differentiated innovation and especially now that we entering are entering. Areas like cardiovascular vascular a significant unmet need. There's tremendous opportunities for us to ensure that we secure a premium pricing for truly differentiated innovations, especially in areas like electrophysiology. Heart recovery with Abbvie Ahmed and more recently with Shockwave. Thank you.

See tremendous opportunity to really secure a premium pricing, especially where we have differentiated innovation and especially now that we entering are entering. Areas like cardiovascular vascular a significant unmet need. There's tremendous opportunities for us to ensure that we secure a premium pricing for truly differentiated innovations, especially in areas like electrophysiology. Heart recovery with Abbvie Ahmed and more recently with Shockwave. Thank you.

Areas like cardiovascular vascular a significant unmet need. There's tremendous opportunities for us to ensure that we secure a premium pricing for truly differentiated innovations, especially in areas like electrophysiology. Heart recovery with Abbvie Ahmed and more recently with Shockwave. Thank you.

There's tremendous opportunities for us to ensure that we secure a premium pricing for truly differentiated innovations, especially in areas like electrophysiology. Heart recovery with Abbvie Ahmed and more recently with Shockwave. Thank you.

Heart recovery with Abbvie Ahmed and more recently with Shockwave. Thank you.

Operator: Thank you. Our next question today is coming from Dave Risinger from Leerink Partners. Your line is now live.

David Risinger: Yes, thanks very much. Could you please comment on the J&J U.S. pharma exposure to efforts by plans to extract greater rebates in 2025 than in typical years in order to offset Part D plan losses in 2025? Thanks very much.

Could you please comment on the J&J U S pharma exposure to efforts by plans to extract greater rebates in 2025 than in typical years in order to offset part D plan losses in 2025, thanks very much.

Jennifer Taubert: Thanks for the question on that. We're still in the process of working with all payers for the planned formularies and everything for 2025 and 2026. I think what's really most important is to go back to the guidance we provided at the EBR last year in November. And as we take a look at the corporation, we have factored in and anticipated what we think will happen. And as an organization, we feel very confident in the guidance of 3% plus growth in 2025, and really, importantly, that accelerating growth out through the end of the decade, the 5% to 7% growth.

For the the plan formulary isn't everything before 2025 and in 2026 I think what's really most important is to go back to the guidance that we've provided at the E. P. Our last year in November and as we take a look at the corporation, we have factored in an anticipated what we think will happen. And as an organization, we feel very confident in our gardens of a 3% plus growth in 2025, and really importantly that accelerating growth out through the end of the decade that that 5% to 7% growth.

And as an organization, we feel very confident in our gardens of a 3% plus growth in 2025, and really importantly that accelerating growth out through the end of the decade that that 5% to 7% growth.

Joseph J. Wolk: Dave, I'd also remind you too that over the last six years, and certainly a compliment to John, Jennifer and the team, that innovation really underscores the success that we've had with quarter in, quarter out performance in our Innovative Medicines business. Discounts and rebates six years ago, as compared to list price was only about 25% of that list price. Today, that number--and this is not just the J&J number, but an industry number, gravitates towards 60%. So what we want to make sure that happens is this great innovation gets to patients and makes a difference in their lives and get them--they have access through the discounting that we already provide.

As compared to list price was only about 25% of that list price today that number and this is not just the J&J number, but an industry number gravitates towards 60%. So what we want to make sure that happens as this great innovation gets to patients and makes a difference in their lives and get them. They have access through the discounting that we already provide.

Operator: Thank you. Next question is coming from Danielle Antalffy from UBS. Your line is now live.

Danielle J. Antalffy: Hey, good morning, everyone. Thanks so much for taking the question. Just a quick MedTech question on China. So China, it sounds like things are evolving in China. I mean this is no surprise to anyone. But just curious about how you guys are thinking about China as a contributor going forward given all the evolution in that market and some of the issues, VBP, things like that. How meaningful? I mean, it's been a big growth driver for you guys historically. How do we think about China going forward? And is the strategy for J&J, does it have to change to adapt to the evolving market there? Thanks so much.

Get in some of the issues the B P things like that how meaningful I mean, it's been a big growth driver for you guys. Historically, how do we think about China going forward and is the strategy for J&J does it have to change to adapt to the evolving market. There. Thanks so much.

Joaquin Duato: Thank you, Danielle, it's Joaquin. So, we were one of the first companies that started to operate in China, and we've been in China for decades. So, we have a history of having constructive engagements with China, and we are looking forward for that to continue. Now we recognize the situation and we have robust business continuity planning practices in place, and we are able to mitigate any potential exposure. But we continue to see China as an important growth driver, both for our Innovative Medicine business and also for our MedTech business. Specifically, you had some questions that Tim can address on MedTech and how we see our MedTech business in China moving forward.

A history of having a constructive engagement with China and we are looking forward for that to continue but we recognize the situation and we have a robust business continuity planning practices in place and are we we are able to mitigate any potential exposure, but we continue to. See China as an important growth driver both for our innovative <unk> seen a business and also for our domestic business. Specifically you had some questions that the team kind of it is on the med Tech and how we see our mid tier business in China moving forward

See China as an important growth driver both for our innovative <unk> seen a business and also for our domestic business. Specifically you had some questions that the team kind of it is on the med Tech and how we see our mid tier business in China moving forward sure and Daniel we are fortunate to have a global business with.

See China as an important growth driver both for our innovative <unk> seen a business and also for our domestic business. Specifically you had some questions that the team kind of it is on the med Tech and how we see our mid tier business in China moving forward

Tim Schmid: Sure. And Danielle, we are fortunate to have a global business with more than 50% of our revenue already out of the U.S. And I think that gives us the flexibility to really manage a number of challenges that occur on a quarterly and yearly basis across the world. To Joaquin's point, we've been in China for 37 years. One of the reasons why we've been successful is our ongoing commitment in navigating multiple headwinds and opportunities. And when we look at our performance in China, remember, we had the end of COVID when we came out of lockdown, and so that has impacted the results in the second quarter. But when you look at on the ground, what's really happening is there's two factors. Firstly, you look at the impact of VBP, which is a government-driven cost containment effort. And given our leadership position in China, we are seeing that as a short-term tailwind. We do believe the volume opportunity will far offset over time the impact we're seeing on price, but that certainly is a short-term pain that we are enduring. That has also been exacerbated by the anticorruption campaign. You may know that in July of last year, the government initiated an anticorruption campaign, which actually has had an impact on both procedural volumes and engagement from health care professionals.

More than 50% of our revenue already out of the U S and I think that gives us the flexibility to really manage a number of challenges that occur you know on a quarterly and yearly basis across the world I don't walk ins. We've been in China for 37 years, one of the reasons why we've been successful is our ongoing commitment to navigating multiple headwinds end to end opportunities and when we look at our performance in China Remember we had the the end of Covid. When we came out of Lockdown and so that has impacted at least that results in the. <unk> quarter, but when you look at on the ground whats really happening is there's two factors firstly because the impact of V. B P, which is a government driven cost containment effort and given our leadership position in China. We are seeing that as a short term tailwind. We do believe the volume opportunity will far offset over time the impacts we're seeing on the on price, but that certainly is a short term. Pain that we are enduring that has also been exacerbated by the Anticorruption campaign you may know that in July of last year. The government initiated an anti corruption campaign, which act, which actually has had an impact on both procedural volumes and engagement from health care professionals

We've been in China for 37 years, one of the reasons why we've been successful is our ongoing commitment to navigating multiple headwinds end to end opportunities and when we look at our performance in China Remember we had the the end of Covid. When we came out of Lockdown and so that has impacted at least that results in the. <unk> quarter, but when you look at on the ground whats really happening is there's two factors firstly because the impact of V. B P, which is a government driven cost containment effort and given our leadership position in China. We are seeing that as a short term tailwind. We do believe the volume opportunity will far offset over time the impacts we're seeing on the on price, but that certainly is a short term. Pain that we are enduring that has also been exacerbated by the Anticorruption campaign you may know that in July of last year. The government initiated an anti corruption campaign, which act, which actually has had an impact on both procedural volumes and engagement from health care professionals

<unk> quarter, but when you look at on the ground whats really happening is there's two factors firstly because the impact of V. B P, which is a government driven cost containment effort and given our leadership position in China. We are seeing that as a short term tailwind. We do believe the volume opportunity will far offset over time the impacts we're seeing on the on price, but that certainly is a short term. Pain that we are enduring that has also been exacerbated by the Anticorruption campaign you may know that in July of last year. The government initiated an anti corruption campaign, which act, which actually has had an impact on both procedural volumes and engagement from health care professionals

Pain that we are enduring that has also been exacerbated by the Anticorruption campaign you may know that in July of last year. The government initiated an anti corruption campaign, which act, which actually has had an impact on both procedural volumes and engagement from health care professionals now I must reiterate that we see.

Pain that we are enduring that has also been exacerbated by the Anticorruption campaign you may know that in July of last year. The government initiated an anti corruption campaign, which act, which actually has had an impact on both procedural volumes and engagement from health care professionals

Tim Schmid: Now I must reiterate that we see this as a really good thing. We believe that any effort on behalf of any government to really build integrity and compliance into the health system is a good thing for more fair competition and aligns with our credo and our commitment to compliance across all of the markets in which we participate in. So, it's a short-term headwind, but long-term, really good for our industry and really good for J&J. We remain absolutely committed to China. And we will continue, as we always have, to navigate some of the challenges we have on the ground with pricing and geopolitical challenges, and we remain committed to the 1.4 billion patients who rely on us each and every day. Thank you.

This is a really good thing we believe that any effort on behalf of any government to really really build integrity and compliance into the health system is a good thing for more fair competition and aligns with our credo in our commitment to compliance across all of the markets in which we participate in so it's a short term headwind, but long term. Really good for our industry and really good for J&J, we remain absolutely committed to China, and we will continue as we always have to navigate. Some of the challenge that we have on the ground with pricing geopolitical challenges and we remain committed to the $1 4 billion patients who rely on us each and every day. Thank you.

Really good for our industry and really good for J&J, we remain absolutely committed to China, and we will continue as we always have to navigate. Some of the challenge that we have on the ground with pricing geopolitical challenges and we remain committed to the $1 4 billion patients who rely on us each and every day. Thank you.

Some of the challenge that we have on the ground with pricing geopolitical challenges and we remain committed to the $1 4 billion patients who rely on us each and every day. Thank you.

Operator: Thank you. Next question today is coming from Chris Shibutani from Goldman Sachs. Your line is now live.

Chris Shibutani: Thank you. Good morning. Together with my colleague, David Roman, a genuine question that we had related to the MedTech market dynamics and outlook. Can you help us better understand comments that were made about a fair amount of inventory destocking that's been happening and juxtapose that and perhaps reconcile with your expectation that the demand outlook would strengthen. We're just trying to put together this notion of inventory stocking, destocking ahead of an anticipated acceleration versus a potential deceleration or a tougher demand environment going forward? That would be helpful. Thank you.

Can you help us better understand comments that were made about a fair amount of inventory destocking, that's been happening and juxtapose that in perhaps reconcile with your expectation that the demand outlook with strengthened which is trying to put together. This notion of inventory stocking destocking ahead of an anticipated acceleration. Versus a potential deceleration of a tougher demand environment going forward that'd be helpful. Thank you.

Versus a potential deceleration of a tougher demand environment going forward that'd be helpful. Thank you.

Joseph J. Wolk: Thank you. It's a good question and the only area across the vast businesses that we have, where we have seen a destocking is really in our contact lens business. And you'll recall in the first quarter, we mentioned that on the back of some historical supply chain challenges, the distributor inventory was reduced here in the U.S., and we've now seen that bleed into the second quarter as mentioned earlier. And so, that is the only area of significant stocking that has had a short-term impact on our business. As I mentioned earlier, what gives us confidence is that as we look through the full second quarter, we saw sequential improvement across that portfolio. Remember that we actually serve the needs of 40 million patients. We have, by far and away, a market leadership position here in the U.S. and globally with contact lenses. And so, we see this as a blip and by no means a longer impact on our ability to continue to be leaders in contact lens. Thank you.

Was reduced here in the U S and we've now seen that bleed into the second quarter as mentioned earlier. And so that is the only area of significant stocking that has had a short term impact on our business as I mentioned earlier, what's gets what gives us confidence is that as we look through the full second quarter, we saw sequential improvement across that portfolio remember that we actually serve the needs of 40 million patients we have by far and away. Market leadership position here in the U S and globally with contact lenses and so we see this as a blip and by no means a longer impact on our ability to continue to be leaders in contact lens. Thank you.

And so that is the only area of significant stocking that has had a short term impact on our business as I mentioned earlier, what's gets what gives us confidence is that as we look through the full second quarter, we saw sequential improvement across that portfolio remember that we actually serve the needs of 40 million patients we have by far and away. Market leadership position here in the U S and globally with contact lenses and so we see this as a blip and by no means a longer impact on our ability to continue to be leaders in contact lens. Thank you.

Market leadership position here in the U S and globally with contact lenses and so we see this as a blip and by no means a longer impact on our ability to continue to be leaders in contact lens. Thank you.

Jessica Moore: Thank you, Chris. And Kevin, we have time for one last question.

Operator: Thank you. Our final question today is coming from Joanne Wuensch from Citibank. Your line is now live.

Joanne K. Wuensch: Thank you very much for taking the question. I'd like to wrap up with the orthopedics question. Hips and knees are growing faster than the historic rates, could you sort of unpack that a little bit and give us an idea of how much of that is patient volume, price, new products or maybe something else? And have a great day.

After than the historical rates could you sort of unpack that a little bit and give us an idea of how much of that is patient volume price your products or maybe something else and have a great day.

Tim Schmid: You too, Joanne, thank you. We are so proud of--frankly, the resurgence of orthopedics, and I couldn't be more grateful for the incredible effort across the world to really return as to high solid growth across the two platforms that you referenced. Specifically within hips, and I mentioned this in the first quarter, for the first time ever, we were able to declare market leadership position in hips here in the U.S. And to be direct in answering your question, it is all innovation based. It's not only continuing to drive our best-in-class implants, but it's also how we've surrounded those with enabling like our VELYS Hip Navigation and Kenzie. That 6% growth you saw in the second quarter is really indicative our innovation working for patients. On knees, another shout out to the team, almost 10% growth. We haven't seen that historically and once again driven by innovation. In a short roughly 2.5-year period, we have launched our VELYS system for knees into more than 20 markets. We have more than 70,000 procedures, and that is driver of our performance. And what gives us confidence is that we're continuing to build indications. You may know in the second quarter, we received 510K approval for our VELYS Uniknee. And we also are looking to build out that portfolio. And in short order, you will see news about our commitment to really bringing robotics to other parts of the orthopedic portfolio, especially in spine. And so once again, it's all innovation driven, and we expect it to continue. Thank you.

Who really returned us too high a solid growth across the two platforms that you referenced specifically with hit within hips and I mentioned this in the first quarter for the first time ever we were able to declare a market leadership position in hips here in the U S and to be direct in answering your question. It is all innovation based its not only. To drive our best in class class implants, but it's also how we've surrounded those with enabling technologies like our Dallas hip navigation and concise that 6% growth you saw in the second quarter was really indicative of our innovation working for patients on knees. Another shout out to the team almost 10% growth we haven't. Seen that historically and once again driven by innovation in a short roughly two and a half year period, we have launched our Venice system for for knees into more than 20 markets. We have more than 70000 procedures. Then that is the key driver of our performance and what gives us confidence is that we're continuing to build. Indications you may know in the second quarter, we received five 10-K approval for our Dallas Uni knee. And we also are looking to build out that portfolio and in short order you will see news about our commitment to really bringing robotics to other parts of the orthopedics portfolio, especially in spine and so once again its all innovation driven. And we expect it to continue thank you.

To drive our best in class class implants, but it's also how we've surrounded those with enabling technologies like our Dallas hip navigation and concise that 6% growth you saw in the second quarter was really indicative of our innovation working for patients on knees. Another shout out to the team almost 10% growth we haven't. Seen that historically and once again driven by innovation in a short roughly two and a half year period, we have launched our Venice system for for knees into more than 20 markets. We have more than 70000 procedures. Then that is the key driver of our performance and what gives us confidence is that we're continuing to build. Indications you may know in the second quarter, we received five 10-K approval for our Dallas Uni knee. And we also are looking to build out that portfolio and in short order you will see news about our commitment to really bringing robotics to other parts of the orthopedics portfolio, especially in spine and so once again its all innovation driven. And we expect it to continue thank you.

Seen that historically and once again driven by innovation in a short roughly two and a half year period, we have launched our Venice system for for knees into more than 20 markets. We have more than 70000 procedures. Then that is the key driver of our performance and what gives us confidence is that we're continuing to build. Indications you may know in the second quarter, we received five 10-K approval for our Dallas Uni knee. And we also are looking to build out that portfolio and in short order you will see news about our commitment to really bringing robotics to other parts of the orthopedics portfolio, especially in spine and so once again its all innovation driven. And we expect it to continue thank you.

Indications you may know in the second quarter, we received five 10-K approval for our Dallas Uni knee. And we also are looking to build out that portfolio and in short order you will see news about our commitment to really bringing robotics to other parts of the orthopedics portfolio, especially in spine and so once again its all innovation driven. And we expect it to continue thank you.

And we also are looking to build out that portfolio and in short order you will see news about our commitment to really bringing robotics to other parts of the orthopedics portfolio, especially in spine and so once again its all innovation driven. And we expect it to continue thank you.

And we expect it to continue thank you.

Jessica Moore: Thank you, Joanne, and thanks to everyone for your questions and your continued interest in our company. We apologize to those that we couldn't get to because of time, but don't hesitate to reach out to the Investor Relations team with any remaining questions you may have. I will now turn the call over to Joaquin for some brief closing remarks.

Joaquin Duato: Thank you, everyone, for joining the call today. I'm proud of the progress we made through the first-half of the year. And I'm also energized as we look towards the remainder of 2024 and heading to 2025. As the only company dedicated to both medical technology and pharmaceuticals, we are uniquely positioned to lead the next wave of health care innovation. We are entering the second-half of the year from a position of strength, advancing our diverse portfolio and pipeline to continue bringing innovation into the patients we serve. Thank you.

Out of the progress we made through the first half of the year and I'm also energized as we look towards the remainder of 'twenty 'twenty four. Heading into 2025. The only company dedicated to both medical technology and Pharmaceuticals, we are uniquely positioned to lead. The next wave of innovation. We are entering the second half of the year from a position of strength. <unk> seen our diverse portfolio. Blind to continue bringing innovation into the patients we serve thank you.

Heading into 2025. The only company dedicated to both medical technology and Pharmaceuticals, we are uniquely positioned to lead. The next wave of innovation. We are entering the second half of the year from a position of strength. <unk> seen our diverse portfolio. Blind to continue bringing innovation into the patients we serve thank you.

The only company dedicated to both medical technology and Pharmaceuticals, we are uniquely positioned to lead. The next wave of innovation. We are entering the second half of the year from a position of strength. <unk> seen our diverse portfolio. Blind to continue bringing innovation into the patients we serve thank you.

<unk> seen our diverse portfolio. Blind to continue bringing innovation into the patients we serve thank you.

Blind to continue bringing innovation into the patients we serve thank you.

Operator: Thank you. This concludes today's Johnson & Johnson second quarter 2024 earnings conference call. You may now disconnect.