How Iran war has triggered soaring cost of medicines

The market is underpricing how quickly a regional air-logistics shock can transmit into global pharma margins even without a true shortage. The first-order hit is not volume, but working-capital stress and gross-margin compression for generics, OTCs, and any product with cold-chain complexity; these are the names least able to absorb a 5-15% freight spike. The second-order winner is the premium logistics layer: air freight forwarders, express carriers, and temperature-controlled packaging providers gain pricing power because pharma cargo has the highest service priority and the least tolerance for substitution.

The more important equity implication is dispersion inside healthcare. Large branded pharma with diversified manufacturing, long inventory days, and higher gross margins should be relatively insulated, while generic-heavy distributors, emerging-market pharmacies, and CMOs exposed to Gulf transshipment routes face inventory resets and margin leakage over the next 1-3 quarters. If airspace disruptions persist, the pain moves beyond OTCs into oncology and biologics because those SKUs force premium air capacity and cannot be flexed to ocean freight.

Consensus may be too focused on “temporary delays” and not enough on behavioral responses: wholesalers will pre-buy, pharmacists will carry more safety stock, and that pulls forward demand just as transport capacity tightens. That creates a classic bullwhip effect where nominal shortages appear late, after spreads have already widened. The key reversal trigger is a durable de-escalation that restores Gulf routing and normalizes jet-fuel economics; absent that, the earnings risk is less about one-off write-downs and more about several quarters of incremental freight and procurement inflation.