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AstraZeneca: CARDIO-TTRansform Phase III Trial For Wainua Fails To Meet Primary Efficacy Endpoint

Healthcare & BiotechCompany FundamentalsRegulation & Legislation

AstraZeneca said its Phase III CARDIO-TTRansform trial of Wainua (with Ionis) in transthyretin-mediated amyloid cardiomyopathy did not meet the primary efficacy endpoint for the composite cardiovascular outcome. The failure to achieve the trial’s main endpoint is a clear clinical setback that is likely to weigh on near-term expectations for the program.

Analysis

AstraZeneca said its Phase III CARDIO-TTRansform trial of Wainua (with Ionis) in transthyretin-mediated amyloid cardiomyopathy did not meet the primary efficacy endpoint for the composite cardiovascular outcome. The failure to achieve the trial’s main endpoint is a clear clinical setback that is likely to weigh on near-term expectations for the program.

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