INmune Bio’s XPro1595 Prevents Brain-Injury-Induced Alzheimer's Pathology, Memory Loss, and Pain in New Peer-Reviewed Preclinical Study

A study links soluble TNF to the biological pathway between head injury and Alzheimer’s, and shows that selectively neutralizing it with XPro1595 prevents injury-induced increases in amyloid pathology. Treated subjects also demonstrated improved early cognitive performance and pain-related outcomes versus controls. The results are promising but appear preclinical/early-stage based on the wording of the article.

Analysis

A study links soluble TNF to the biological pathway between head injury and Alzheimer’s, and shows that selectively neutralizing it with XPro1595 prevents injury-induced increases in amyloid pathology. Treated subjects also demonstrated improved early cognitive performance and pain-related outcomes versus controls. The results are promising but appear preclinical/early-stage based on the wording of the article.