Post-hoc analyses from the acoramidis initiation show rapid kidney-protective activity, including a reversible hemodynamically mediated eGFR dip and a placebo-corrected 15.5% reduction in UACR by Day 28 (P<0.05). No kidney-related adverse events were observed in these analyses, supporting a cautiously positive efficacy and safety signal.
Post-hoc analyses from the acoramidis initiation show rapid kidney-protective activity, including a reversible hemodynamically mediated eGFR dip and a placebo-corrected 15.5% reduction in UACR by Day 28 (P<0.05). No kidney-related adverse events were observed in these analyses, supporting a cautiously positive efficacy and safety signal.
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mildly positive
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0.35