Zacks Investment Research promotes its Earnings ESP tool, which identifies potential earnings surprises by comparing the most accurate analyst estimate to the consensus. This methodology, when combined with a Zacks Rank #3 (Hold) or better, has historically predicted positive earnings surprises 70% of the time, leading to an average annual return of 28.3% over a 10-year backtest. The article highlights medical stocks GSK (+4.74% ESP) and Gilead Sciences (+0.77% ESP), both with a Zacks Rank #3, as current examples poised to beat upcoming earnings estimates in July and August 2025, respectively. This systematic approach offers investors a data-driven method for identifying short-term trading opportunities around quarterly reports.
The analysis centers on a quantitative signal, the Zacks Earnings Expected Surprise Prediction (ESP), which indicates a heightened probability of upcoming earnings beats for two medical sector stocks, GSK (GSK) and Gilead Sciences (GILD). According to the methodology, a combination of a positive ESP and a Zacks Rank of #3 (Hold) or better has historically preceded a positive earnings surprise 70% of the time. GSK exhibits a particularly strong signal with a +4.74% ESP, derived from a Most Accurate Estimate of $1.15 per share versus a consensus of $1.10 ahead of its July 30, 2025 report. Gilead Sciences shows a more modest, yet still positive, signal with a +0.77% ESP, based on a Most Accurate Estimate of $1.98 versus a $1.97 consensus for its August 14, 2025 earnings. While both stocks carry a neutral #3 (Hold) rating, suggesting they are expected to perform in-line with the broader market, the positive ESPs from recent analyst revisions present a potential short-term, event-driven catalyst.
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