Q1 2026 Verrica Pharmaceuticals Inc Earnings Call

May 12, 2026

Speaker #3: Please stand by. Your meeting is about to begin. Good day, ladies and gentlemen, and welcome to the Verrica Pharmaceuticals First Quarter 2026 earnings conference call.

Operator: Good day, ladies and gentlemen, and welcome to the Verrica Pharmaceuticals Q1 2026 Earnings Conference Call. At this time, all participants are in a listen-only mode. After the speaker's remarks, there will be a question and answer session. As a reminder, this conference is being recorded. I will now turn the call over to our host, Kevin Gardner of LifeSci Advisors. You may begin your conference.

Speaker #3: At this time, all participants are in a listen-only mode. After the speaker's remarks, there will be a question-and-answer session. As a reminder, this conference is being recorded.

Speaker #3: I will now turn the call over to our host, Kevin Gardner, of LifePsy Advisors. You may begin your conference.

Speaker #2: Thank you, operator. Hello, everyone, and welcome to Verrica Pharmaceuticals First Quarter 2026 corporate update conference call. With me on the line this evening are Jayson Rieger, president and chief executive officer; Noah Rosenberg, chief medical officer; John Kirby, interim chief financial officer; David Zawits, chief operating officer; and Chris Chapman, chief commercial officer.

Kevin Gardner: Thank you, operator. Hello, everyone, and welcome to Verrica Pharmaceuticals First Quarter 2026 Corporate Update Conference Call. With me on the line this evening are Jayson Rieger, President and Chief Executive Officer, Noah Rosenberg, Chief Medical Officer, John J. Kirby, Interim Chief Financial Officer, David Zawitz, Chief Operating Officer, and Chris Chapman, Chief Commercial Officer. As a reminder, during today's call, management will make forward-looking statements. These forward-looking statements are based on the company's current expectations and involve inherent risks and uncertainties. Verrica's actual results and the timing of events could differ materially from those anticipated in such forward-looking statements. Please see Verrica's SEC filings for important risk factors. Verrica cautions you not to place undue reliance on forward-looking statements and undertakes no duty or obligation to update any forward-looking statements as a result of new information, future events, or changes in expectations.

Speaker #2: As a reminder, during today's call, management will make forward-looking statements. These forward-looking statements are based on the company's current expectations and involve inherent risks and uncertainties.

Speaker #2: Verrica's actual results and the timing of events could differ materially from those anticipated in such forward-looking statements. Please see Verrica's SEC filings for important risk factors.

Speaker #2: Verrica cautions you not to place undue reliance on forward-looking statements and undertakes no duty or obligation to update any forward-looking statements as a result of new information, future events, or changes in expectations.

Speaker #2: In addition, during today's call, management will discuss certain non-GAAP financial measures. These non-GAAP financial measures are an addition to and not a substitute for or superior to measures of financial performance prepared in accordance with GAAP.

Kevin Gardner: In addition, during today's call, management will discuss certain non-GAAP financial measures. These non-GAAP financial measures are in addition to and not a substitute for or superior to measures of financial performance prepared in accordance with GAAP. There are a number of limitations related to the use of these non-GAAP financial measures compared to their closest GAAP equivalents. The earnings release that the company issued today includes GAAP to non-GAAP reconciliations for these measures and is also available on the investor relations section of Verrica's website. I'll now turn the call over to Verrica's President and CEO, Jayson Rieger.

Speaker #2: There are a number of limitations related to the use of these non-GAAP financial measures, compared to their closest GAAP equivalents. The earnings release that the company issued today includes GAAP-to-non-GAAP reconciliations for these measures, and is also available on the investor relations section of Verrica's website.

Speaker #2: I'll now turn the call over to Verrica's president and CEO, Jayson Rieger.

Speaker #3: Thank you, Kevin. Good evening, everyone, and thank you for joining us on our first quarter 2026 corporate update call. I am pleased to report that in the first quarter, we saw accelerating growth in market demand for YCAMP, setting new records for dispensed applicator units during the quarter and in the month of March.

Jayson Rieger: Thank you, Kevin. Good evening, everyone, and thank you for joining us on our Q1 2026 Corporate Update Call. I am pleased to report that in Q1, we saw accelerating growth in market demand for YCANTH, setting new records for dispensed applicator units during the quarter and in the month of March. This growth continued after the end of the quarter as we observed further increased demand in April. YCANTH also achieved another significant milestone in February as our partner, Torii Pharmaceutical, launched YCANTH in Japan for patients with molluscum following their regulatory approval last year. Our hope is that Japan is only the beginning of our global expansion efforts for YCANTH as we are actively working to expand the availability of YCANTH into new markets around the world. While we grow the YCANTH business, we're also advancing our product portfolio.

Speaker #3: This growth continued after the end of the quarter as we observed further increased demand in April. YCAMP also achieved another significant milestone in February, as our partner, Tory Pharmaceutical, launched YCAMP in Japan for patients with molluscum, following their regulatory approval last year.

Speaker #3: Our hope is that Japan is only the beginning of our global expansion efforts for YCAMP, as we are actively working to expand the availability of YCAMP into new markets around the world.

Speaker #3: While we grow the YCAMP business, we're also advancing our product portfolio. As you may recall, in January we announced that the first patient had been dosed in our global Phase III program for the treatment of common warts, which represents a critical milestone in our strategy to expand into new indications.

Jayson Rieger: As you may recall, in January, we announced that the first patient had been dosed in our global Phase III program for the treatment of common warts, which represents a critical milestone in our strategy to expand into new indications. I'm proud to announce that we have achieved more than 50% of the currently targeted enrollment in the first Phase III trial, also known as COVE-2, and have begun enrolling patients in the long-term follow-up study, COVE-4, in this program. Our target is to initiate the second Phase III trial, known as COVE-3, in this program by mid-2026. We also continue to advance our Phase III-ready asset, VP-315, for the treatment of basal cell carcinoma as we've begun efforts to secure clinical supplies and select a CRO to support initiation of the Phase III program.

Speaker #3: I'm proud to announce that we have achieved more than 50% of the currently targeted enrollment in the first Phase III trial, also known as COVE2, and have begun enrolling patients in the long-term follow-up study COVE4 in this program.

Speaker #3: Our target is to initiate the second Phase III trial known as COVE3 in this program by mid-2026. We also continue to advance our Phase III-ready asset BP315 for the treatment of basal cell carcinoma, as we have begun efforts to secure clinical supplies and select a CRO to support initiation of the Phase III program.

Speaker #3: BP315 is garnering increasing attention within the dermatology community based on compelling proof-of-concept data from our Phase II program. I'll now provide a detailed update on our YCAMP commercial business.

Jayson Rieger: VP-315 is garnering increasing attention within the dermatology community based on compelling proof-of-concept data from our phase II program. I'll now provide a detailed update on our YCANTH commercial business. In Q1 2026, we reported total revenue of $5 million, including US YCANTH product revenue of $4.3 million, which was up 25.4% over Q1 2025. Q1 US YCANTH dispensed applicator units increased to 15,302, growing 51.3% over Q1 2025. On a sequential basis, US YCANTH revenue and dispensed applicator units increased 15.3% and 12.1% respectively compared to Q4 2025.

Speaker #3: In the first quarter of 2026, we reported total revenue of $5 million. Including US YCAMP product revenue, a $4.3 million, which was up 25.4% over the first quarter of 2025.

Speaker #3: First quarter U.S. YCAMP dispensed applicator units increased to 15,302, growing 51.3% over the first quarter of 2025. On a sequential basis, U.S. YCAMP revenue and dispensed applicator units increased 15.3% and 12.1%, respectively, compared to the fourth quarter of 2025.

Speaker #3: As noted in our last call in March, while demand for YCAMP in January was likely impacted by severe winter weather across the East Coast, demand accelerated sharply in February and continued into March, which saw the best monthly dispensed applicator unit total since the launch of YCAMP.

Jayson Rieger: As noted in our last call in March, while demand for YCANTH in January was likely impacted by severe winter weather across the East Coast, demand accelerated sharply in February and continued into March, which saw the best monthly dispensed applicator unit total since the launch of YCANTH. As we have now seen preliminary results for April, I am pleased to note that April dispensed applicator units also increased from March's then record level and our team worked diligently every day to help more healthcare providers treat molluscum with what we believe to be is the best treatment available, YCANTH.

Speaker #3: As we have now seen preliminary results for April, I am pleased to note that April dispensed applicator units also increased from March's then-record level, and our team worked diligently every day to help more healthcare providers treat molluscum with what we believe to be is the best treatment available: YCAMP.

Speaker #3: As we've noted in prior quarters, and as we continue to prioritize the ease of access for healthcare providers and their patients, we continue to make substantial investments in our copay assistance program.

Jayson Rieger: As we've noted in prior quarters, as we continue to prioritize the ease of access for healthcare providers and their patients, we continue to make substantial investments in our co-pay assistance program, which is impacted during the first few months of each year by the annual reset of insurance plan deductibles in January. To ensure the broadest access to YCANTH for healthcare providers, we launched YcanthRx, our non-dispensing pharmacy, in Q4 2025. YcanthRx simplifies the process for both the healthcare provider and patient by performing an initial benefit investigation and then triaging to an in-network dispensing pharmacy based upon the patient's unique healthcare coverage. Although YcanthRx is still in the early stage of rollout, it is being well-received and, in our view, will help further drive demand and coverage for YCANTH.

Speaker #3: This is impacted during the first few months of each year by the annual reset of insurance plan deductibles in January. To ensure the broadest access to YCAMP for healthcare providers, we launched YCAMP Rx, our non-dispensing pharmacy, in the fourth quarter of 2025.

Speaker #3: YCAMP Rx simplifies the process for both the healthcare provider and patient by performing an initial benefit investigation and then triaging to an in-network dispensing pharmacy, based upon the patient's unique healthcare coverage.

Speaker #3: Although YCAMP Rx is still in the early stage of rollout, it is being well received. And in our view, will help further drive demand and coverage for YCAMP.

Speaker #3: We would again like to congratulate Tory Pharmaceutical, now a subsidiary of Shinogi, on their February commercial launch of YCAMP in Japan, for patients with molluscum.

Jayson Rieger: We would again like to congratulate Torii Pharmaceutical, now a subsidiary of Shionogi, on their February commercial launch of YCANTH in Japan for patients with molluscum. This milestone reflects the culmination of significant efforts by many team members from both companies. The launch of YCANTH in Japan means that the commercial supply we provide to Torii has begun to offset Verrica's portion of the clinical costs for the common wart program. As we announced in February, we also brought on board Chris Chapman as our new Chief Commercial Officer in Q1. Chris and his team are already doing an outstanding job in optimizing our resources to maximize the productivity of the YCANTH commercial efforts.

Speaker #3: This milestone reflects the culmination of significant efforts by many team members from both companies. The launch of YCAMP in Japan means that the commercial supply we provide to Tory has begun to offset Verica's portion of the clinical costs for the common wart program.

Speaker #3: As we announced in February, we also brought on board Chris Chapman as our new chief commercial officer in the first quarter. Chris and his team are already doing an outstanding job in optimizing our resources to maximize the productivity of the YCAMP commercial efforts.

Speaker #3: Finally, as noted on our fourth quarter call, the Committee for Medicinal Products for Human Use of the European Medicines Agency provided positive feedback that supports the filing of a marketing authorization application for YCAMP as a treatment for molluscum.

Jayson Rieger: Finally, as noted on our Q4 call, the Committee for Medicinal Products for Human Use of the European Medicines Agency provided positive feedback that supports the filing of a marketing authorization application for YCANTH as a treatment for molluscum. With no further Phase III clinical trials required for product approval, we are actively progressing through the next steps for submission in the EU. The EU represents a substantial market opportunity for YCANTH, and we look forward to evaluating potential commercialization partnerships in this large and underserved region. With respect to our pipeline, the common warts and basal cell carcinoma clinical programs continue to move ahead, representing what we believe can be multi-billion dollar opportunities. As I mentioned, in December 2025, we dosed the first patient in the first Phase III trial, COVE-2, evaluating YCANTH for common warts, which continues to enroll patients.

Speaker #3: With no further Phase III clinical trials required for product approval, we are actively progressing through the next steps for submission in the EU. The EU represents a substantial market opportunity for YCAMP, and we look forward to evaluating potential commercialization partnerships in its large and underserved region.

Speaker #3: With respect to our pipeline, the common warts and basal cell carcinoma clinical programs continue to move ahead, representing what we believe can be multibillion-dollar opportunities.

Speaker #3: As I mentioned in December of 2025, we dosed the first patient in the first Phase III trial COVE2, evaluating YCAMP for common warts, which continues to enroll patients.

Speaker #3: The second Phase III trial in the common wart program COVE3, with sites in both the United States and Japan, is targeted to be initiated by mid-2026.

Jayson Rieger: The second Phase III trial in the common wart program, COVE-3, with sites in both the United States and Japan, is targeted to be initiated by mid-2026. If the Phase III program is successful, YCANTH could become the first therapy ever approved in the United States and Japan to treat common warts, a condition that impacts over 22 million people in the US alone. As a reminder, Verrica and Torii will split the cost of the program 50/50, with Torii funding the first 40 million of trial costs, representing approximately 90% of the current trial budget. We expect to repay our portion by offsetting future transfer payments, milestones, and royalties relating to YCANTH sales in Japan.

Jayson Rieger: The second phase III trial in the common wart program, COVE-3, with sites in both the United States and Japan, is targeted to be initiated by mid-2026. If the Phase III program is successful, YCANTH could become the first therapy ever approved in the United States and Japan to treat common warts, a condition that impacts over 22 million people in the US alone. As a reminder, Verrica and Torii will split the cost of the program 50/50, with Torii funding the first 40 million of trial costs, representing approximately 90% of the current trial budget. We expect to repay our portion by offsetting future transfer payments, milestones, and royalties relating to YCANTH sales in Japan.

Speaker #3: If the Phase III program is successful, YCAMP could become the first therapy ever approved in the United States and Japan to treat common warts.

Speaker #3: A condition that impacts over 22 million people in the US alone. As a reminder, Verica and Tory will split the costs of the program 50/50, with Tory funding the first $40 million of trial costs representing approximately 90% of the current trial budget.

Speaker #3: We expect to repay our portion by offsetting future transfer payments milestones and royalties relating to YCAMP sales in Japan. As a reminder, all of the efforts we are undertaking for the commercialization of YCAMP for molluscum lay the foundation for ultimate commercialization for the common warts indication if approved, and there will be significant overlap in the clinician's treating both molluscum and common warts.

Jayson Rieger: As a reminder, all of the efforts we are undertaking for the commercialization of YCANTH for molluscum lay the foundation for ultimate commercialization for the common warts indication, if approved, and there will be significant overlap in the clinicians treating both molluscum and common warts, with the ability to access the same applicator through the same distribution channels. With respect to VP-315 for basal cell carcinoma, our program continues to drive strong interest with clinicians and patients alike as potential alternative approach to the existing surgical and non-surgical options. In our phase II study, treatment with VP-315 demonstrated a 97% objective response rate and an 86% reduction in overall tumor size, with more than half of the treated lesions achieving complete histological resolution. We continue to share additional data from the ongoing analysis of the results from the phase II at scientific conferences.

Speaker #3: With the ability to access the same applicator through the same distribution channels. With respect to VP315 for basal cell carcinoma, our program continues to drive strong interest with clinicians and patients alike, as potential alternative approach to the existing surgical and nonsurgical options.

Speaker #3: In our Phase II study, treatment with VP315 demonstrated a 97% objective response rate and an 86% reduction in overall tumor size. With more than half of the treated lesions achieving complete histological resolution.

Speaker #3: We continue to share additional data from the ongoing analysis of the results from the Phase II at scientific conferences. As reported last week, we will formally be presenting at the 2026 Society for Investigative Dermatology, or SID, at their annual meeting in Chicago later this week.

Jayson Rieger: As reported last week, we will formally be presenting at the 2026 Society for Investigative Dermatology, or SID, at their annual meeting in Chicago later this week, and we'll be sharing additional data regarding the abscopal-like observations from the phase II study. With a strong scientific foundation from our phase II results and regulatory engagement, we have also recently completed several market research activities to better understand how VP-315 would be received by various stakeholders. This work supports broad potential utilization and acceptance across general dermatologists, medical oncologists, and Mohs surgeons, as well as office managers and payers. We also conducted market research to evaluate the patient perspective, which indicated that a substantial majority of patients would elect to try VP-315 before other existing therapeutic options, regardless of whether they had previously been treated for skin cancer.

Speaker #3: And we'll be sharing additional data regarding the EBSCOPA-like observations from the Phase II study. With our strong scientific foundation from our Phase II results and regulatory engagement, we have also recently completed several market research activities to better understand how VP315 would be received by various stakeholders.

Speaker #3: This work supports broad potential utilization and acceptance across general dermatologists, medical oncologists, and mode surgeons as well as office managers and payers. We also conducted market research to evaluate the patient perspective which indicated that a substantial majority of patients would elect to try VP315 before other existing therapeutic options.

Speaker #3: Regardless of whether they had previously been treated for skin cancer. While the best outcome for patients is to completely eliminate the tumor, which we have observed in many patients in our Phase II study, overall tumor size was reduced on an average of by 86%, which we view as clinically meaningful.

Jayson Rieger: While the best outcome for patients is to completely eliminate the tumor, which we have observed in many patients in our phase II study, overall tumor size was reduced on an average of by 86%, which we view as clinically meaningful. This highlights the potential for VP-315 to improve the patient experience by reducing the size of the and potential complexity of future procedures, even where surgical excision is ultimately required. In totality, this market research reinforces our conviction and enthusiasm for the potential of VP-315 to change the paradigm for treatment of basal cell carcinoma. We continue to actively assess a variety of funding opportunities for this program and have initiated clinical and CMC activities to proactively prepare for the commencement of the phase III program.

Speaker #3: This highlights the potential for VP315 to improve the patient experience by reducing the size of the potential complexity of future procedures, even where surgical excision is ultimately required.

Speaker #3: In totality, this market research reinforces our conviction and enthusiasm for the potential of VP315 to change the paradigm for treatment of basal cell carcinoma.

Speaker #3: We continue to actively assess a variety of funding opportunities for this program and have initiated clinical and C activities to proactively prepare for the commencement of the Phase III program.

Speaker #3: As previously noted, Verica has retained 100% global commercial rights to YCAMP for all approved and potential indications outside of Japan as well as full global rights to VP315 for non-metastatic skin cancers including basal, cell, and squamous cell carcinoma.

Jayson Rieger: As previously noted, Verrica has retained 100% global commercial rights to YCANTH for all approved and potential indications outside of Japan, as well as full global rights to VP-315 for non-metastatic skin cancers, including basal cell and squamous cell carcinoma. These programs represent a robust opportunity for potential partnership to create shareholder value, and optimize global access to patients that can benefit most from these medicines. I'll now turn over the call to our Interim Chief Financial Officer, John Kirby, to review our first quarter 2026 financials.

Speaker #3: These programs represent a robust opportunity for potential partnership to create shareholder value and optimize global access to patients that can benefit most from these medicines.

Speaker #3: I'll now turn over the call to our interim chief financial officer, John Kirby, to review our first quarter 2026 financials.

Speaker #2: Thanks, Jason. I'll now take a few minutes to summarize our financial results for the first quarter ended March 31st, 2026. Total revenue for the first quarter of 2026 was $5 million, consisting of $4.3 million of US net YCAMP revenue and $0.7 million of licensed and collaboration revenue, associated with our Tory partnership, compared to $3.4 million of US net YCAMP revenue and $17,000 of licensed and collaboration revenue in the first quarter of 2025.

John J. Kirby: Thanks, Jayson. I'll now take a few minutes to summarize our financial results for Q1 ended 31 March 2026. Total revenue for Q1 2026 was $5 million, consisting of $4.3 million of US net YCANTH revenue, and $0.7 million of license and collaboration revenue associated with our Torii partnership, compared to $3.4 million of US net YCANTH revenue, and $17,000 of license and collaboration revenue in Q1 2025. Net YCANTH revenue in Q1 2026 reflects shipments to our distribution partners, offset by standard gross to net adjustments, including actual or anticipated product returns, off-invoice discounts, distribution fees, rebates, and co-pay assistance program expenses.

Speaker #2: Net YCAMP revenue in the first quarter of 2026 reflects shipments to our distribution partners, offset by standard gross-to-net adjustments, including actual or anticipated product returns, off-invoice discounts, distribution fees, rebates, and copay assistance program expenses.

Speaker #2: Gross product margins for the first quarter of 2026 were $87.3% compared to gross product margins of $87.6% for the prior year period. Cost of product revenue for the first quarter of 2026 was $0.5 million, versus $0.4 million for the prior year period, consisting primarily of product costs related to the sale of YCAMP.

John J. Kirby: Gross product margins for Q1 2026 were 87.3% compared to gross product margins of 87.6% for the prior year period. Cost of product revenue for Q1 2026 was $0.5 million versus $0.4 million for the prior year period, consisting primarily of product costs related to the sale of YCANTH. Research and development expenses of $3.9 million in Q1 2026 increased by $1.5 million when excluding the impact of stock-based compensation, compared to $2.3 million in Q1 2025 due to increased spend on the common warts program.

Speaker #2: Research and development expenses of $3.9 million in the first quarter of 2026 increased by $1.5 million when excluding the impact of stock-based compensation, compared to $2.3 million in the first quarter of 2025, due to increased spend on the common warts program.

Speaker #2: Selling general and administrative expenses of $10 million in the first quarter of 2026 increased by $1.3 million when excluding the impact of stock-based compensation compared to the expense of $8.8 million in the first quarter of 2025, driven primarily by increased commercial spend related to the expansion of our sales force.

John J. Kirby: Selling, general and administrative expenses of $10 million in Q1 2026 increased by $1.3 million when excluding the impact of stock-based compensation, compared to the expense of $8.8 million in Q1 2025, driven primarily by increased commercial spend related to the expansion of our sales force. GAAP net loss was $9.7 million, or $0.45 per share for Q1 2026, compared to a GAAP net loss of $9.7 million or $1.03 per share for Q1 2025.

Speaker #2: Gap net loss was $9.7 million or 45 cents per share for the first quarter of 2026, compared to a gap net loss of $9.7 million or $1.03 per share for the first quarter of 2025.

Speaker #2: On a non-gap basis, which excludes stock-based compensation, non-cash interest expense, and change in fair value of embedded derivatives, the first quarter of 2026 net loss was $8.8 million or 41 cents per share, compared to a net loss of $8.3 million or 88 cents per share for the first quarter of 2025.

John J. Kirby: On a non-GAAP basis, which excludes stock-based compensation, non-cash interest expense and change in fair value of embedded derivatives, the Q1 2026 net loss was $8.8 million, or $0.41 per share, compared to a net loss of $8.3 million, or $0.88 per share for the Q1 2025. Finally, as of 31 March 2026, Verrica had aggregate cash of $20.6 million, which is expected to fund operations into the Q1 2027. I'll now turn the call back over to Jayson for closing remarks.

Speaker #2: And finally, as of March 31, 2026, Verrica had aggregate cash of $20.6 million, which is expected to fund operations into the first quarter of 2027.

Speaker #2: I'll now turn the call back over to Jason for closing remarks.

Speaker #3: Thanks, John. We are steadfastly advancing our efforts to establish YCAMP as the new standard of care for molluscum and are seeing traction with our strongest quarter in dispensed applicator units since launch.

Jayson Rieger: Thanks, John. We are steadfastly advancing our efforts to establish YCANTH as the new standard of care for molluscum and are seeing traction with our strongest quarter in dispensed applicator units since launch. We are also positioning our company to fully capture the significant opportunities which lie ahead for our advanced stage pipeline if these programs successfully complete their development and are approved. Based on our phase II data, the feedback from the dermatology community, and alignment with the FDA on the phase III program design, we believe VP-315 truly has the potential to fundamentally change the treatment paradigm of basal cell carcinoma. In addition, the opportunity to expand YCANTH label into common warts would open in a new addressable patient population for which there currently remains no FDA-approved therapies.

Speaker #3: We are also positioning our company to fully capture the significant opportunities which lie ahead for our advanced-stage pipeline if these programs successfully complete their development and are approved.

Speaker #3: Based on our Phase II data, the feedback from the dermatology community, and alignment with the FDA on the Phase III program design, we believe VP315 truly has the potential to fundamentally change the treatment paradigm of basal cell carcinoma.

Speaker #3: In addition, the opportunity to expand YCAMP's label into common warts would open in a new addressable patient population for which there are currently remains no FDA-approved therapies.

Speaker #3: We believe each of these two opportunities represents significant potential upside for our company, and for our shareholders, and we are excited about the future for Verica and the potential impacts for patients.

Jayson Rieger: We believe each of these two opportunities represents significant potential upside for our company and for our shareholders, and we are excited about the future for Verrica and the potential impacts for patients. With that, we'd be happy to answer your questions. Operator?

Speaker #3: With that, we'd be happy to answer your questions. Operator?

Speaker #4: Thank you. And if you would like to ask a question, please press star one on your keypad. To leave the queue at any time, press star two.

Operator 3: Thank you. If you would like to ask a question, please press star 1 on your keypad. To leave the queue at any time, press star 2. Once again, that is star and 1 to ask a question. We'll take our first question from Stacy Ku with TD Cowen. Please go ahead. Your line is open.

Operator: Thank you. If you would like to ask a question, please press star 1 on your keypad. To leave the queue at any time, press star 2. Once again, that is star and 1 to ask a question. We'll take our first question from Stacy Ku with TD Cowen. Please go ahead. Your line is open.

Speaker #4: Once again, that is star and one to ask a question. We'll take our first question from Stacey Ku with TD Cowen. Please go ahead.

Speaker #4: Your line is open.

Speaker #5: Hey there. Thanks so much for taking our questions. Congratulations on the enrollment progress for your common warts program, and for YCAMP. First, consensus for the year seems to be around kind of the mid-$20 million range.

Stacy Ku: Hey there. Thanks so much for taking our questions. Congratulations on the enrollment progress for your common warts program, and also on the quarter for YCANTH. First, consensus for the year seems to be around kind of the mid $20 million kind of range. To the extent that you can comment, what are your views given what seems to be very encouraging growing demand in April? That's the first question. Second, I know this can be a little location specific, are you expecting to see seasonality with molluscum this year, and what are you doing to ensure you can capture any type of increased rates in the summertime? Would you also assume the YCANTH prescription hub services to start driving adoption and improve installment around that timeframe?

Speaker #5: To the extent that you can comment, what are your views given what seems to be very encouraging growing demand in April? So that's the first question.

Speaker #5: And then second, I know this can be a little location-specific, but are you expecting to see seasonality with molluscum this year? And what are you doing to ensure you can capture any type of increase rates in the summertime?

Speaker #5: Would you also assume the YCAMP prescription hub services to start driving adoption and improving fulfillment around that timeframe? So that's the second question. The third is to get an update on the progress of expanding the sales force in regions that you're seeing good YCAMP adoption.

Stacy Ku: That's the second question. The third is to get an update on the progress of expanding the sales force in regions that you're seeing good YCANTH adoption. Just help us understand what you're seeing in terms of the additional stepwise expansion, and if we should expect any additional updates with the sales force. Just help us understand the progress when it comes to YCANTH adoption and also maybe potentially YCANTH access. And then last, as you think about VP-315, just maybe help us understand as you think about phase III, where you expect the product to be positioned in the BCC treatment paradigm. What type of patient profile for BCC would opt for a product like this? Thanks so much.

Speaker #5: So just help us understand what you're seeing in terms of the additional stepwise expansion and if we should expect any additional updates with the sales force to help us understand the progress when it comes to YCAMP adoption and also maybe potentially YCAMP access.

Speaker #5: And then last, as you think about VP315, just maybe help us understand as you think about Phase III, where you expect the product to be positioned in the BCC treatment paradigm.

Speaker #5: What type of patient profile for BCC would opt for a product like this? Thanks so much.

Jayson Rieger: Thank you, Stacy. Appreciate it. I think I made good notes on all of your questions. I'm sure you'll correct me if I miss any. Starting with the consensus, you know, we're very excited about the progress we're making. You know, we saw, you know, a good ending to the Q1, you know, solid performance so far, you know, in April, we're excited about the prospects of the year. You know, it's premature to give guidance at this point, we're gonna leave that, you know, number alone.

Speaker #3: Thank you, Stacey. Appreciate it. I think I made good notes on all of your questions. I'll do my best, but I'm sure you'll correct me if I miss any.

Speaker #3: Starting with the consensus, we're very excited about the progress we're making. We saw a good ending to the Q1, solid performance so far in April.

Speaker #3: And we're excited about the prospects of the year. It's premature to give guidance at this point. So we're going to leave that number alone.

Speaker #3: But what we're seeing right now, it gives us confidence on the growth that we're seeing and the performance over the course of the year.

Jayson Rieger: What we're seeing right now, it gives us confidence on, you know, the growth that we're seeing and the performance over the course of the year. With regards to seasonality, depending on, you know, where you look and who you ask, you know, there's all kinds of comments on when the seasonality would be. Overall, I think there's general consensus to see growth as you enter the spring and summertime, and I think that's where we are right now, and that could be contributing to some of the growth we're seeing. A lot of it also comes down to the execution on the commercial side and the general, you know, adoption of YCANTH that we're starting to see. I'll let Chris comment a little more on your questions regarding the sales force and the sales focus, you know, in a moment.

Speaker #3: But with regards to seasonality, depending on where you look and who you ask, there's all kinds of comments on when the seasonality would be.

Speaker #3: But overall, I think there's general consensus to see growth as you enter the spring and summertime. And I think that's where we are right now and that could be contributing to some of the growth we're seeing.

Speaker #3: But a lot of it also comes down to the execution on the commercial side and the general adoption of YCAMP that we're starting to see.

Speaker #3: And I'll let Chris comment a little more on your questions regarding the sales force and the sales focus in a moment. But one of those tools that's certainly going to help, and we're starting to see some adoption, is the YCAMP RX in our hub to help support the routing of scripts and, importantly, the fulfillment of scripts facilitating it for the clinicians and the patients to make that access as easy as possible.

Jayson Rieger: One of those tools that's certainly going to help, and we're starting to see some adoption, is the YcanthRx in our hub to help support, you know, the routing of scripts and importantly, fulfillment of scripts, facilitating it for the clinicians and the, and the patients to make that access as easy as possible. I'll let Chris comment a few minutes on your question on the commercial side, and then I'll round out the YCANTH, on VP-315.

Speaker #3: I'll let Chris comment a few minutes on your question on the commercial side, and then I'll round out the YCAMP on 315.

Speaker #1: Thank you, Stacey, for the question. And as Jason mentioned in the opening, I joined in March and I've been very pleased with what I've found in the organization.

Chris Chapman: Thank you, Stacy, for the question. You know, as Jayson mentioned in the opening, I joined in March, and I've been very pleased with what I've found in the organization, but there are areas for optimization. You mentioned the field force. Currently we are deployed, and our territories do capture about 85% of the TAM. However, there are areas that we can optimize reach and frequency, and we are going through a kind of stem to stern reach and frequency exercise. We will be staffing to about approximately 50 representatives. There are numerous markets that could use additional manpower. I think you're seeing in the momentum that we're building, slight tweaks to our deployment and our execution are yielding some momentum, and I remain cautiously optimistic on that.

Speaker #1: But there are areas for optimization. You mentioned the field force. Currently, we are deployed in our territories do capture about 85% of the TAM.

Speaker #1: However, there are areas that we can optimize reach and frequency. And we are going through a kind of STEM to STERN reach and frequency exercise we will be staffing to about approximately 50 representatives.

Speaker #1: There are numerous markets that could use additional manpower. And I think you're seeing in the momentum that we're building a slight tweaks to our deployment, our execution, our yielding some momentum.

Speaker #1: And I remain cautiously optimistic on that. But again, we're totally reevaluating our current targeting to optimize that reach and frequency which, again, gives us the opportunity to optimize 85% that we're already deployed against.

Chris Chapman: Again, we're totally reevaluating our, current targeting, to optimize that reach and frequency, which again gives us the opportunity to optimize 85% that we're already deployed against.

Speaker #3: Thanks, Chris. And then I'll let Noah comment a little bit on your question on VP315.

Jayson Rieger: Thanks, Chris. I'll let Noah comment a little bit on your question on, VP-315.

Speaker #6: In terms of our Phase III program, our initial approach is to target patients with low-risk BCC, i.e., nodular and superficial, and to target similar population to what we saw in Phase II.

Noah Rosenberg: In terms of our phase III program, our initial approach is to target patients with low-risk BCC, i.e., nodule and superficial, and to target similar populations that we saw in phase II. Those would be primary tumors. I think broadly beyond phase III, I think it's important to also recognize that we see this as potentially long-term neoadjuvant approach for complex and difficult to treat tumors, and very excited about the abscopal data, which has some implications potentially for patients who often present with multiple lesions at initial presentation.

Speaker #6: Those would be primary tumors. I think, broadly, beyond Phase III, it's important to also recognize that we see this as potentially, long-term, a neoadjuvant approach for complex and difficult-to-treat tumors.

Speaker #6: And very excited about the obscopal data, which has some implication potentially for patients who often present with multiple lesions at initial presentation.

Jayson Rieger: Thanks, Noah. Thanks, Chris. You know, to round that out, one of the feedback that we've generally seen from patients we've asked about their perspective on this treatment is those who are naive to ever having had treatment with basal cell or those who have had multiple basal cell experiences before seem to be very receptive towards the potential of VP-315 as a method as their first line of therapy, to try and see if they can reduce the size or perhaps completely eliminate the lesion. That bodes well both for them as well as if proceeds down to Mohs or other procedures where that lesion is smaller and that surgical procedure would be simpler, in terms of complication, potential scarring, side effects, et cetera.

Speaker #3: Thanks, Noah. And thanks, Chris. And to round that out, one of the feedback that we've generally seen from patients that we've asked about their perspective on this treatment is those who are naive to ever having had treatment with basal cell or those who have had multiple basal cell experiences before seem to be very receptive towards the potential of VP315 as a method to as their first line of therapy.

Speaker #3: To try and see if they can reduce the size, or perhaps completely eliminate the lesion. And that bodes well both for them, as well as if it proceeds down to Mohs or other procedures where that lesion is smaller and that surgical procedure would be simpler in terms of complication, potential scarring, side effects, etc.

Speaker #4: Super helpful. Thank you as always.

Stacy Ku: Super helpful. Thank you, as always.

Speaker #3: Thanks, Stacey.

Jayson Rieger: Thanks, Stacy.

Speaker #5: Thank you. We will move next with Dennis Ding with Jefferies. Please go ahead.

Operator 3: Thank you. We will move next with Dennis Ding with Jefferies. Please go ahead.

Operator: Thank you. We will move next with Dennis Ding with Jefferies. Please go ahead.

Georgia Bank: Hello, this is Georgia Bank on the line for Dennis Ding. Thank you for taking our questions and congratulations on the quarter. I guess another question on the VP-315 program and on the SID data. I guess showing reductions in untreated lesions consistent with the potential abscopal effect, how are you thinking about validating that signal going forward? How should we think about the opportunity of that market where patients might have multiple lesions versus just a single, and what would that look like? A follow-up on the YcanthRx pharmacy model and how it's performing today, and what proportion of scripts are routed through that pharmacy, and what are you seeing in terms of differences in prescription to treatment conversions or reimbursement success rates and so on?

Speaker #7: Hello. This is Georgia Bank. On the line for Dennis Ding. Thank you for taking our questions and congratulations on the quarter. I guess another question on the 315 program and data.

Speaker #7: I guess showing reductions in untreated lesions consistent with the potential obscopal effect, how are you thinking about validating that signal going forward? And how should we think about the opportunity of the market where patients might have multiple lesions versus just a single?

Speaker #7: And what would that look like? And then a follow-up on the YCAMP RX pharmacy model and how it's performing today and what proportion of scripts are routed through that pharmacy and what are you seeing in terms of differences in prescription-to-treatment conversions or reimbursement success rates and so on?

Speaker #6: So it's Noah here. I think in terms of the obscopal effect and the overall implications the patient population I think many patients present initially with multiple lesions often patients, especially those who've already had procedures want a surgical alternative.

Noah Rosenberg: It's Noah here. I think in terms of the abscopal effect and the overall implications to the patient population, I think many patients present initially with multiple lesions. Often patients, especially those who've already had procedures, want a surgical alternative. Again, we see this as complementary to surgery, but in some cases, patients may not want that surgery, and in some cases they've got more than one lesion. We believe that this data, while early and exploratory, is extremely encouraging. In terms of validating that data, we plan, as we've mentioned, two larger studies, 100 patients each in phase III, and we'll be able to explore and look at larger populations and look at that abscopal effect.

Speaker #6: So again, we see this as complementary to surgery. But in some cases, patients may not want that surgery. And in some cases, they've got more than one lesion.

Speaker #6: So we believe that this data while early and exploratory is extremely encouraging. In terms of validating that data, we plan, as we've mentioned, to larger studies 100 patients each in Phase III.

Speaker #6: And we'll be able to explore and look at larger populations and look at that abscopal effect. I think it's important to note that, regardless of whether the patients were contralateral or they were nearby in terms of the lesions, we still saw effects broadly.

Noah Rosenberg: I think it's important to note that regardless of whether the patients were contralateral or they were nearby in terms of the lesions, we still saw effects broadly, and I think that was extremely encouraging, and we're very excited to embark on that data.

Speaker #6: And I think that was extremely encouraging. And we're very excited to embark on that data.

Speaker #8: This is David Zowitz speaking on YCAMP RX. The YCAMP RX performance has been good in the early few months since we launched it. It's an option that we provide to the prescribers who are looking to write the product.

David Zawitz: This is David Zawitz speaking on YcanthRx. The YcanthRx performance has been good in the early few months since we launched it. It's an option that we provide to the prescribers who are looking to write the product. It's not, you know, mandatory. They can choose to write it if they are looking for the additional help with benefits investigations and with potentially processing prior auth if they're required. So far, you know, we've been improving the program throughout the quarter since the launch, and it's been going well. We're not gonna comment right now on sort of percentage of our total business that's running through that. The adoption is growing and it's gonna be proving to be a useful option for prescribers who are looking to use it.

Speaker #8: It's not mandatory. They can choose to write it if they are looking for the additional help with benefits investigations and with potentially processing and prior auths if they're required.

Speaker #8: And so far, we've been improving the program throughout the quarter since the launch. And it's been going well. And we're not going to comment right now on sort of percentage of our total business that's running through that.

Speaker #8: But the adoption is growing. And it's going to be it is proving to be a useful option for prescribers who are looking to use it.

Speaker #7: Understood. Thank you.

Georgia Bank: Understood. Thank you.

Speaker #5: Thank you. We will move next with Serge Bellinger with Needham Company. Please go ahead. Your line is open.

Operator 3: Thank you. We will move next with Serge Belanger with Needham & Company. Please go ahead. Your line is open.

Operator: Thank you. We will move next with Serge Belanger with Needham & Company. Please go ahead. Your line is open.

Speaker #9: Hi. Good afternoon. Thanks for taking our questions. First one, I guess, just on the one Q performance. Just trying to understand the variability from quarter to quarter and intergross to nets to reconcile the difference between the applicator unit growth and sales number.

Serge Belanger: Hi, good afternoon. Thanks for taking the questions. First one, I guess just on the Q1 performance, just trying to understand the variability from quarter to quarter and in your gross-to-nets to reconcile the difference between the applicator unit growth and sales number. Secondly, can you maybe just talk about the competitor molluscum product that's currently in the market, whether it's been a headwind for YCANTH or maybe there's been a tailwind due to the additional voice in the market promoting molluscum? Thanks.

Speaker #9: And then secondly, can you maybe just talk about the competitor molluscum product that's currently in the market, whether it's been a headwind for YCAMP, or maybe if there's been a tailwind due to the additional voice in the market promoting molluscum?

Speaker #9: Thanks.

Speaker #3: Serge, thanks for the question. As Chris Chapman and I think the variation certainly that you see between Q4 and Q1. Q4 historically is a the most valuable month for manufacturers most of the patients have cleared their deductibles.

Chris Chapman: Serge, thanks for the question. It's Chris Chapman. You know, I think the variation certainly that you see between Q4 and Q1, you know, Q4 historically is the most valuable month for manufacturers. You know, most of the patients have cleared their deductibles, and people are refilling their prescriptions. Q1, you do have the deductible reset, I think we saw a little bit of that. As I mentioned in my prior comments, you know, I'm really encouraged at the momentum that we saw coming out of Q1 into the first month of Q2. There are a couple of reasons, and they all relate to the questions that have been asked here. One is YcanthRx, which provides a useful option for those physicians who need some additional support.

Speaker #3: And people are refilling their prescriptions. Q1, you do have the deductible reset. So I think we saw a little bit of that. But as I mentioned in my prior comments, I'm really encouraged at the momentum that we saw coming out of Q1 into the first month of Q2.

Speaker #3: And there are a couple of reasons. And they all relate to the questions that have been asked here. One is YCAMP RX. Which provides a useful option for those physicians who need some additional support.

Speaker #3: The other is you mentioned is having additional share of voice. Having a second competitor in the market driving recognition and choosing to treat molluscum is a huge opportunity.

Chris Chapman: The other, as you mentioned, is having additional share of voice. Having a second competitor in the market driving recognition and choosing to treat molluscum is a huge opportunity that we certainly are taking advantage of. The third, as I mentioned, being, you know, new to Verrica, is the opportunity to do some basic optimization on reach and frequency on your targets. I think those three areas. Again, I would anticipate you're continue to gonna see a synergistic effect of share of voice in the marketplace as well as those additional, you know, commercial levers that we're pulling. Expect to see, you know, more guidance as we get into Q3 and Q4. Right now, as I mentioned, cautiously optimistic, but impressed with the early results that we see.

Speaker #3: That we certainly are taking advantage of. The third, as I mentioned, being new to Verica is the opportunity to do some basic optimization. On reach and frequency on your targets.

Speaker #3: And so I think those three areas but again, I would anticipate your continued going to see a synergistic effect of share of voice in the marketplace as well as those additional commercial levers that we're pulling.

Speaker #3: Expect to see more guidance as we get into Q3 and Q4. But right now, as I mentioned, cautiously optimistic. But impressed with the early results that we see.

Jayson Rieger: Thanks, Chris. As I said, you know, Serge Belanger, to follow up, you know, what we've seen is this is a market dominated by, you know, a watch and wait mentality. Now that we have a viable option for treatment, and we believe, you know, YCANTH really addresses the unmet need by, you know, 1 to 2 treatments on average for most patients to get to a resolution that they're happy with in terms of their disease. We believe that will continue adoption and convert those from watching to actually getting treated. Awareness of the disease and that there's therapies out there, you know, bodes well for our program.

Speaker #9: Thanks, Chris. And as I said, Serge, to follow up, what we've seen is this is a market dominated by a watch and wait mentality.

Speaker #9: And now that we have a viable option for treatment and we believe YCAMP really addresses the unmet need by 1 to 2 treatments on average for most patients to get to a resolution that they're happy with in terms of their disease, we believe that will continue adoption and convert those from watching to actually getting treated.

Speaker #9: And awareness of the disease and that there's therapies out there both well for our program.

Speaker #3: Thank you.

Serge Belanger: Thank you.

Speaker #5: Thank you. We will move next with. From Silva Raju with HC Wainwright. Please go ahead.

Operator 3: Thank you. We will move next with Ram Selvaraju with H.C. Wainwright. Please go ahead.

Operator: Thank you. We will move next with Ram Selvaraju with H.C. Wainwright. Please go ahead.

Speaker #10: Thanks so much for taking our questions. Just with respect to Europe, could you maybe elaborate on how you anticipate reference pricing to shake out as and when the product ultimately becomes eligible for market entry?

Ram Selvaraju: Thanks so much for taking our questions. Just with respect to Europe, could you maybe elaborate on how you anticipate reference pricing to shake out, as and when the product ultimately becomes eligible for market entry? If you could give us a sense of post-approval, what the country-by-country cadence might be, which countries are most likely to be first in line, for YCANTH introduction? Thank you.

Speaker #10: And also, if you could give us a sense of post-approval, what the country-by-country cadence might be? Which countries are most likely to be first in line for YCAMP introduction?

Speaker #10: Thank you.

Speaker #3: Thanks, Rob. I appreciate that. We're still in the early stages of our Europe planning and strategy works. We have ongoing activities with regards to understanding pricing and pricing options.

Jayson Rieger: Thanks, Ram. I appreciate that. You know, we're still in the early stages of our Europe planning and strategy works. We have ongoing activities with regards to understanding pricing and pricing options and what reimbursement might look like there. We have explored that in a number of countries, and we're gonna share that information as, you know, it's right to do so. In terms of countries, we're planning to have broad access across the EU. Obviously, there are some strategies on which countries may come first. In that, I would say we will probably be more consistent with traditional European rollouts. But we're gonna evaluate that based on the feedback on a country-by-country basis and the addressable population, as well as the pricing that may differentiate across those countries.

Speaker #3: And what reimbursement might look like there. We have explored that in a number of countries. And we'll continue to share that information as it's ripe to do so.

Speaker #3: In terms of countries, we're planning to have a broad access across the EU. Obviously, there are some strategies on which countries may come first in that.

Speaker #3: I would say we will probably be more consistent with traditional European rollouts. But we're going to evaluate that based on the feedback on a country-by-country basis.

Speaker #3: And the addressable population as well as the pricing that may differentiate across those countries. But that work is ongoing. In parallel to our work to complete the regulatory submission activities.

Jayson Rieger: That work is ongoing in parallel to our work to complete the regulatory submission activities.

Speaker #10: Can you also just briefly comment on any underlying emergent trends among both unique prescribers and repeat prescribers of YCAMP that you're seeing in the most recent data?

Ram Selvaraju: Can you also just briefly comment on any underlying emergent trends among both unique prescribers and repeat prescribers of YCANTH, that you're seeing in the most recent data?

Speaker #9: Yeah. I can speak to that. And we're seeing what you would expect to see. The dermatologist dominate the early adoption. And you see that across classes.

Chris Chapman: Yeah. I can speak to that. We're seeing what you would expect to see, that the dermatologists dominate the early adoption. You see that across classes. You also see it across competitors in this space. As you would imagine, you're also seeing repeat prescribing in those earliest adopters. As we continue to expand that prescriber pool, you see more and more pediatricians coming in. You know, clearly, those are the two largest segments. As you might imagine, dermatologists were the early adopters. In molluscum, in the selection to both diagnose and to treat and to retreat additional patients.

Speaker #9: You also see it across competitors. In this space, and as you would imagine, you're also seeing repeat prescribing in those earliest adopters. As we continue to expand that prescriber pool, you see more and more pediatricians coming in.

Speaker #9: So clearly, those are the two largest segments. But as you might imagine, dermatologists were the early adopters. In molluscum, in the selection to both diagnose and to treat.

Speaker #9: And to retreat additional patients.

Speaker #10: Thank you.

Jayson Rieger: Thank you.

Speaker #5: Thank you. We will move next with Camp Doliver with Brookline Capital Markets. Please go ahead.

Operator 3: Thank you. We will move next with Kemp Dolliver with Brookline Capital Markets. Please go ahead.

Operator: Thank you. We will move next with Kemp Dolliver with Brookline Capital Markets. Please go ahead.

Speaker #11: Great. Thank you. What do you see as the gating factors behind demand now? If you look back over the history of the launch, there was reimbursement.

Kemp Dolliver: Great. Thank you. What do you see as the gating factors behind demand now? You know, if you look back over the history of the launch, you know, there was reimbursement, there was compounded product in a lot of offices and on the market. You know, what do you see is the key things you need to overcome at this stage, assuming that those, the first couple things I mentioned have been resolved?

Speaker #11: There was compounded product in a lot of offices. And on the market. How do you see what do you see as the key things you need to overcome at this stage?

Speaker #11: Assuming that those first couple of things I mentioned have been resolved.

Speaker #9: Yeah. I don't know if I would call access resolved. Certainly, we've achieved a steady state and a target access. Now we have the need to pull it through.

Chris Chapman: Yeah. I don't know if I would, if I would call access, resolved. Certainly, we've achieved a steady state and a target access. Now we have the need to pull it through, you know, into the children accounts of the PBM. There are still geographic opportunities for us to pull it through. I think the real gating factor is what you kind of hear a theme in my answers here. It's appropriate targeting and segmentation. You know, of course, we need to get that early adoption, and we need to get trial. As you get into the pediatric segment, as Jayson mentioned, you know, the biggest competitor is watchful waiting. It's not that molluscum is not seen. It's with the prior lack of approved FDA-approved medications, it wasn't treated.

Speaker #9: Into the children accounts of the PBM. So there are still geographic opportunities for us to pull it through. But I think the real gating factor is what you kind of hear a theme in my answers here.

Speaker #9: It's appropriate targeting and segmentation. Of course, we need to get that early adoption. And we need to get trial. But as you get into the pediatric segment, as Jason mentioned, the biggest competitor is watchful waiting.

Speaker #9: And it's not that molluscum is not seen. It's with the prior lack of approved FDA-approved medications, it wasn't treated. And so now the gating factor to us is to drive trial.

Chris Chapman: Now the gating factor to us is to drive trial. YCANTH works, and when we see physicians trial it, they rewrite it. For us, it's continuing to grow those prescribers concentrically out from the early adopters, from those deciles 10s, nines, eights, getting down into those lower decile physicians, which will take us in more into that pediatric segment. That becomes the real unique opportunity here in the next three to four quarters.

Speaker #9: YCAMP works. And when we see physicians trial it, they rewrite it. So for us, it's continuing to grow those prescribers, concentrically out from the early adopters, from those deciles 10s, 9s, 8s, getting down into those lower decile physicians which will take us in more into that pediatric segment.

Speaker #9: So that becomes the real unique opportunity here in the next three to four quarters.

Jayson Rieger: Yeah. Kemp, to add to that.

Speaker #3: And to add to that, oh, go ahead, please.

Kemp Dolliver: Can I just?

Jayson Rieger: Oh, go ahead, please.

Speaker #11: Oh, I was just going to follow up on that last point. Have you looked at whether there's a correlation between seniority of physician and willingness to trial?

Kemp Dolliver: I was just gonna say, follow up on that last point. Have you looked at whether there's a correlation between seniority of physician and willingness to trial?

Chris Chapman: When you mean seniority, what do you mean by that?

Speaker #9: When you mean seniority, can you what do you mean by that?

Chris Chapman: When you mean seniority, what do you mean by that?

Kemp Dolliver: Age. I'm sorry, age.

Speaker #11: Age. I'm talking about age.

Speaker #9: Oh, interesting.

Chris Chapman: Oh, interesting.

Speaker #11: Physician medical schools are used to they're used to teach them not to worry about it when you look at the senior physicians because there were no options.

Kemp Dolliver: Because in medical schools, they used to teach them not to worry about it when you look at the senior physicians because there were no options.

Speaker #11: But.

Speaker #9: Yeah. Not necessarily. But I will tell you this. Where we do see some differential is your physician extenders. Those on the front lines in the trenches, your nurse practitioners, your PAs.

Chris Chapman: Yeah. Not necessarily, but I will tell you this, where we do see some differential is your physician extenders, those on the front lines and the trenches, your nurse practitioners, your PAs. They are very open to treating. So I guess in a way, you know, you might be able to extrapolate that to age. I think that's more of a relevant dynamic or the nurse extenders, or physician extenders. Yeah, I really don't see it as age. I will say, you know, dermatology as a whole is very familiar with cantharidin. Primary care, less so. I think the trial that we've seen early is to be expected. The adoption that we're now seeing in dermatology is to be expected, and the opportunity remains as we expand out into pediatricians.

Speaker #9: They are very, very open to treating. And so, I guess in a way, you might be able to extrapolate that to age. But I think that's more of a relevant dynamic.

Speaker #9: Are the nurse extenders or physician extenders? But yeah, I really don't see it as age. But I will say, dermatology as a whole is very familiar with cetheridin.

Speaker #9: Primary care less so. So I think the trial that we've seen early is to be expected. The adoption that we're now seeing in dermatology is to be expected.

Speaker #9: And the opportunity remains as we expand out into pediatricians.

Speaker #3: And Kim, to follow up, two more points to address some of your comments. We've spent the last year working on distribution and access and availability of the product for clinicians who want to treat.

Jayson Rieger: Kemp, to follow up.

Kemp Dolliver: Thank you

Jayson Rieger: Two more points to address with some of your comments. You know, we've spent the last year working on distribution and access and availability of the product for clinicians who wanna treat. This quarter, we just announced in our release, which we crossed over 100,000 applicator that have been dispensed since launch. You know, one of the things, as Chris refers to the early adopters versus starting to expand beyond that, you start to get a critical amount of adoption and utilization outside post-clinical trials. That gives the later adopters and those who like to watch and take their time, data to see that the safety profile is consistent with what we saw in the clinical studies, the efficacy is being consistent with what we've seen.

Speaker #3: And this quarter, as we just announced in our release, we crossed over 100,000 applicators that have been dispensed since launch. One of the things, as Christopher said, is to the early adopters versus starting to expand beyond that, you start to get a critical amount of adoption.

Speaker #3: And utilization outside post-clinical trials. And that gives the later adopters and those who like to watch and take their time data to see that the safety profile is consistent with what we saw in the clinical studies.

Speaker #3: The efficacy is being consistent with what was seen. And so both of those things really bode well for those next wave of adopters to start to come aboard.

Jayson Rieger: Both of those things really bode well for, you know, those next wave of adopters to start to come aboard. We've worked very hard to make it the access to be easy with our co-pay support, you know, our medical education, you know, and, you know, just awareness of the product for treatment of molluscum.

Speaker #3: And we've worked very hard to make the access easy—with our copay support, our medical education, and just awareness of the product for treatment of molluscum.

Speaker #11: Thank you.

Kemp Dolliver: Thank you.

Operator 3: Thank you. We will move next with Dev Prasad with Lucid Capital Markets. Please go ahead.

Operator: Thank you. We will move next with Dev Prasad with Lucid Capital Markets. Please go ahead.

Speaker #5: Thank you. We will move next with Dev Prasad with Lucid Capital Markets. Please go ahead.

Speaker #12: Thank you for taking our question and congrats on the progress. I have a couple. One, following up to the last one, I'm not sure if you answered it or not.

Dev Prasad: Thank you for taking our question, and congrats on the progress. I have a couple. One, following up from the last one, I'm not sure if you answered it or not, but are you seeing YCANTH growth primarily from new prescriber entering this launch curve or from higher utilization from existing high volume account? Second is, what are the next gating steps for EU submission and potential launch? Thank you.

Speaker #12: But are you seeing YCAMP growth primarily from new prescriber entering this launch curve? Or from higher utilization from existing high-volume account? And second is what are the next gating steps for EU submission and potential launch?

Speaker #12: Thank you.

Speaker #9: Thanks for the question. And we're really seeing both. Those prescribers who trialed early are continuing to prescribe, but we are seeing a much quicker acceleration as we get into that early majority segment of the physician cohort.

Chris Chapman: Thanks for the question. We're really seeing both. Those prescribers who trialed early are continuing to prescribe, but we are seeing a much quicker acceleration as we get into that early majority segment of the physician cohort. I think we're gonna continue. We have to drive both. Of course, when you do have a competitor come out, those earliest adopters are gonna trial that brand, which is a good thing. We are seeing continued growth in both segments, and we'll continue to focus on the highest deciles, 10 through 8, to make sure that we, you know, we have that secure as we continue to expand, you know, into the rest of the market.

Speaker #9: So I think we're going to continue. We have to drive both, of course. When you do have a competitor come out, those earliest adopters are going to trial that brand.

Speaker #9: Which is a good thing. But we are seeing continued growth in both segments. And we'll continue to focus on the highest deciles 10 through 8 to make sure that we have that secure as we continue to expand into the rest of the market.

Speaker #3: And with regards to Europe, there's obviously a number of steps that you have to go through. We have received our racial scientific advice regarding the general scope of what a submission would look like for approval.

Jayson Rieger: With regards to Europe, you know, there's obviously a number of steps that you have to go through. We have received our initial scientific advice regarding the general scope of what a submission would look like for approval. We need to go through the process, you know, for example, securing, you know, pediatric investigation waivers, repertoire assignments, et cetera. We're going through that process now. As indicated previously, you know, Verrica has retained global rights to YCANTH outside the United States, except for Japan, which is, you know, controlled by Torii. We have those rights, you know, we'll continue to explore that, you know, for a European partner to support both the commercialization process to address some of the earlier questions as well.

Speaker #3: Now, we need to go through the process—for example, securing pediatric investigation waivers, rapid tour assignment, etc. And so, we're going through that process now.

Speaker #3: And as indicated previously, Verica has retained global rights to YCAMP outside of the United States, except for Japan, which is controlled by Tori. If we have those rights and we'll continue to explore that for European partner to support both the commercialization process to address some of the earlier questions as well.

Speaker #12: Great. Thank you.

Dev Prasad: Great. Thank you.

Speaker #3: Yep.

Jayson Rieger: Yep.

Speaker #5: Thank you. And at this time, there are no further questions in queue. I will now turn the meeting back to CEO Jason Rieger, for closing comments.

Operator 3: Thank you. At this time, there are no further questions in queue. I will now turn the meeting back to CEO, Jayson Rieger, for closing comments.

Operator: Thank you. At this time, there are no further questions in queue. I will now turn the meeting back to CEO, Jayson Rieger, for closing comments.

Speaker #3: Thank you, operator. And thank you, everyone, for your time and attention. I'd like to thank you for joining us this evening. And we look forward to providing more updates on our progress throughout 2026.

Jayson Rieger: Thank you, operator, and thank you everyone for your time and attention. I'd like to thank you for joining us this evening, and we look forward to providing more updates on our progress throughout 2026. Have a nice evening.

Speaker #3: Have a nice evening.

Operator 3: Thank you. This brings us to the end of today's meeting. We appreciate your time and participation. You may now disconnect.

Operator: Thank you. This brings us to the end of today's meeting. We appreciate your time and participation. You may now disconnect.